@import url('https://fonts.googleapis.com/css2?family=Ubuntu:wght@300;400;500;700&display=swap');

.btc-home-banner-bg {
    /*background: url(/content/dam/website-services/us/434-imfinzi-com/dec-hcp/home/Desktop%20Walker%20Art.png) no-repeat;*/
    background: url(/content/dam/website-services/us/434-imfinzi-com/dec-hcp/home/home-hero-image.jpg) no-repeat;
    background-size: 100%;
    background-color: #002440;
    background-position-y: -35px;
}

.bar-container {
    /*display : flex;*/
}

.pink-bracket { color: #ff5eff; }

.biliary-tract-cancers.btc-hcp ul.data-bullet{list-style-type: none;}
.biliary-tract-cancers.btc-hcp .pinch-zoom-image.mobile-only{/*max-width: 50%;*/margin: 10px auto 0;}

.now-app-overlay {
    /*background: url(/content/dam/website-services/us/434-imfinzi-com/dec-hcp/home/Desktop%20Violator%20blue%20shape.png) no-repeat;*/
    background: url(/content/dam/website-services/us/434-imfinzi-com/dec-hcp/home/blue-box_desktop.png) no-repeat;
    background-size: 100% 127%;
    width: 76.5%;
    max-width: 1025px;
    padding: 11px 0px;
    position: relative;
    /* top: -12px; */
    top: -5px;
    left: -9px;
    display: inline-flex;
    align-items: center;
    /* height: 75px; */
    z-index: 1;
}

.now-app-overlay img {
    margin-left: 78px;
    margin-right: 16px;
    margin-top: 4px;
    width: 87px;
}

.now-app-overlay p {
    color: #ffffff;
    font-size: 26px;
    font-family: 'Ubuntu', sans-serif;
    line-height: 32px;
    font-weight: 700;
    position: relative;
    margin-bottom: 0;
    margin-top: 4px;
    max-width: 640px;
}

#banner-block .bar-container {
    display: flex;
    flex-direction: column;
}
.now-app-overlay.now-app-overlay-2 {
    background: url(/content/dam/website-services/us/434-imfinzi-com/dec-hcp/home/red-angled-box_desktop.svg) no-repeat;
    background-size: 97%;
    /* max-width: 633px; */
    max-width: 689px;
    /* padding: 15px 0px 15px 36px; */
    padding: 15px 0px 15px 0px;
    position: relative;
    width: 100%;
    text-align: center;
    top: -14px;
    /* left: -5px; */
    left: -13px;
    justify-content: center;
}
.now-app-overlay.now-app-overlay-2 sup{
    font-size: 63%;
}
.now-app-overlay.now-app-overlay-2 p {
    color: #ffffff;
    font-size: 26px;
    font-family: 'Ubuntu', sans-serif;
    line-height: 38px;
    font-weight: 700;
    /* position: relative; */
    margin-bottom: 0;
    margin-top: 0;
    text-align: center;
}

.head-1 {
    text-shadow: 1px 2px 2px #000000;
    color: #fff;
    font-size: 55px;
    /* line-height: 48px; */
    line-height: 52px;
    font-family: "Ubuntu", sans-serif;
    font-weight: 700;
    text-align: center;
    margin-bottom: 30px;
}
.head-1 sup{
    top: -14px;
}
.callout-container {
    width: 27.5%;
    /* float: right; */
    position: absolute;
    display: inline-block;
    /* top: -109px; */
    /* top: -70px; */
    top: 82px;
    right: 0px;
}

.callout-open {
    background: url(/content/dam/website-services/us/434-imfinzi-com/dec-hcp/home/callout-open.png) no-repeat content-box;
    background-size: 104% 100%;
    /*height: 329px;*/
    position: relative;
    top: -1px;
	min-height: 244px;
    width: 100%;
 }

.nccn-category-bar {
    display: flex;
    border-top: 1px solid #707070;
    border-bottom: 1px solid #707070;
    background-color: #7099D326;
    position: relative;
    top: 53px;
    left: 1px;
    width: 96%;
    height: auto;
    margin-left: auto;
    margin-right: auto;
    padding-bottom: 7px;
    right: 3px;
}

.nccn-category-text {
	font-size: 17px;
    color: #003262;
    font-family: 'Ubuntu', sans-serif;
    padding: 11px;
    line-height: 13px;
    padding-top: 44px;
}

.nccn-category-text::after {
    content: " ";
    border-right: 1px solid #00294E;
    position: absolute;
    top: 8%;
    bottom: 8%;
    margin-left: 10px;
    height: 80%;
}

.category-text {
    font-size: 13px;
    font-weight: 700;
    font-family: 'Ubuntu', sans-serif;
    width: 83px;
    display: inline-block;
}
.ncc-bold {
    font-weight: 700;
    font-size: 28px;
    font-family: 'Ubuntu', sans-serif;
}
.preferred-text {
    font-size: 14px;
    font-family: 'Ubuntu', sans-serif;
    font-weight: 700;
}

.nccn-expanded-text {
    padding-top: 10px;
    padding-right: 4px;
}

.nccn-expanded-text p {
    margin-bottom: 0px;
    font-family: 'Ubuntu', sans-serif;
    color: #003262;
    font-size: 12px;
    line-height: 13px;
    margin-left: 10px;
}

.nccn-expanded-text:first-child {
    font-weight: 700;
        }

.bar-footnote-container {
	margin-top: 59px;
    padding-left: 4px;
    padding-right: 6px;
    margin-left: 13px;
    margin-right: 0px;
    text-align: left;
    padding-bottom: 19px;
}

.bar-footnote {
    font-size: 12px;
    line-height: 14px;
    font-family: 'Ubuntu', sans-serif;
    font-weight: 400;
    text-indent: -5px;
    margin-bottom: 2px;
}

 .callout-closed {
	background: url(/content/dam/website-services/us/434-imfinzi-com/dec-hcp/home/callout-closed.png) no-repeat content-box;
    background-size: 103% 100%;
    height: 75px;
    position: relative;
    top: 0px;
    display: none;
 }

.callout-closed p {
    padding-top: 20px;
    margin-left: 32px;
}

.nccn-heading{
    font-size: 27px;
    font-family: 'Ubuntu', sans-serif;
    font-weight: 700;
    color: #002650;
}

.nccn-heading::after {
    content: " ";
    color: #002650;
    border-right: 1px solid #002650;
    position: relative;
    top: 5px;
    font-size: 34px;
    left: -2px;
}

.nccn-recommendation {
    font-size: 15px;
    color: #00355A;
    margin-left: 1px;
    position: relative;
    font-family: 'Ubuntu', sans-serif;
    font-weight: 700;
    top: -2px;
    left: 3px;
}
.down-image-open {
	width: 28px;
    float: right;
    position: relative;
    top: 27px;
    right: 0;
    left: -14px;
    transform: rotate(180deg);
    cursor: pointer;
}

.down-image-closed {
    width: 28px;
    margin-left: 14px;
    position: relative;
    top: -2px;
    left: -4px;
    cursor: pointer;
}

.home-heading h1 {
    display: flex;
    width: 100%;
    justify-content: space-between;
    margin: 0 auto;
    padding: 14% 0 17%;
    max-width: 575px;
    font-size: 64px;
    line-height: 76px;
    color: #ffffff;
    font-weight: 700;
    font-family: 'Ubuntu', sans-serif;
}
.home-heading h1 > span:first-child{
    padding-left: 6%;
    position: relative;
    left: -20px;
}
.home-heading h1 > span:last-child{
    padding-left: 13%;
    position: relative;
    left: -3px;
}
.home-heading h1 span.wh-box {
    color: #003865;
    font-size: 21px;
    line-height: 22px;
    background: #ffffff;
    display: block;
    margin: 0px 5px 0;
    padding: 6px 0;
    text-align: center;
    text-shadow: none;
    font-weight: 700;
    font-family: 'Ubuntu', sans-serif;
}
.heading-subh {
    color: #FFFFFF;
    font-size: 26px;
    line-height: 26px;
    padding: 0px 0;
    text-align: center;
    /* max-width: 969px; */
    margin-left: auto;
    margin-right: auto;
    font-family: 'Ubuntu', sans-serif;
    font-weight: 700;
    text-shadow: 0px 0px 15px #000000;
    padding-top: 250px;
}
.white-background {
    background-color: #fff;
    max-width: 1140px;
    margin: 0 auto;
    padding: 20px;
}
.white-background .first-text {
    color: #003262;
    max-width: 705px;
    margin: 0 auto;
    text-align: center;
    font-family: 'Ubuntu', sans-serif;
    /* font-weight: 700; */
    font-size: 18px;
}
/* .reference-section sup {
    top:-0.4em;
    font-size: 64%;
} */
.red-text {
    color: #AC182E;
    font-weight: 700;
}
.bold-text {
    font-weight: 700;
}
.banner-data-sec {
    display: flex;
    margin: 0 auto 0px;
    width: 100%;
    justify-content: center;
    max-width: 1088px;
}
.banner-data-sec > div {
    width: 50%;
}
.banner-data-sec .data-img-sec {
    max-width: 632px;
}
.data-img-sec {
    background: #ffffff;
    padding: 5px 30px 10px;
}
.box-image {
    border: 0.5px solid #03315D;
    max-width: 680px;
    margin: 30px auto;
    /* padding: 20px; */
    padding: 20px 15px 10px 20px !important;
    margin: 30px auto 0;
}
h2.box-heading {
    /*font-size: 16px;
    line-height: 18px;
    letter-spacing: 0.03px;
    color: #003466;
    font-weight: 700;
    position: relative;
    padding: 2px 6px 0 13px;
    background: #ffffff;
    margin-top: -31px;
    width: fit-content;
    max-width: 354px;
    font-family: 'Ubuntu', sans-serif;
    font-weight: 700;*/
    font-size: 16px;
    line-height: 18px;
    letter-spacing: 0.03px;
    color: #003466;
    font-weight: 700;
    position: relative;
    padding: 2px 6px 0 15px;
    background: #ffffff;
    margin-top: -38px;
    width: fit-content;
    max-width: 354px;
    font-family: 'Ubuntu', sans-serif;
    font-weight: 700;
}
h2.box-heading:before {
    content: '';
    background: url(/content/dam/website-services/us/434-imfinzi-com/dec-hcp/dec-subpages/callout-arrow.svg) no-repeat;
    width: 48px;
    background-size: 100%;
    height: 29px;
    position: absolute;
    left: -42px;
    top: 2px;
}
h3.head3 {
    font-size: 22px;
    line-height: 23px;
    color: #003262;
    font-weight: 700;
    letter-spacing: -0.33px;
    font-family: 'Ubuntu', sans-serif;
    margin: 4px 0 0;
}
.box-image-light-blue {
    border: 0.5px solid #617e99;
    max-width: 100%;
    margin: 30px auto;
    /* padding: 20px; */
    padding: 20px 15px 20px 20px !important;
    margin: 30px auto 0;
}
.box-heading-light-blue {
	font-size: 16px;
    line-height: 18px;
    letter-spacing: 0.03px;
    color: #00355a;
    font-weight: 700;
    position: relative;
    padding: 0 6px 0 14px;
    background: #ffffff;
    /*margin-top: -31px;*/
    /*width: fit-content;
    max-width: 560px;*/
    /*max-width: 510px;*/
    margin-top: -31px;
    max-width: 605px;
    font-family: 'Ubuntu', sans-serif;
}
.box-heading-light-blue:before {
	content: '';
    background: url(/content/dam/website-services/us/434-imfinzi-com/dec-hcp/home/dark-blue-arrow.png) no-repeat;
    width: 48px;
    background-size: 100%;
    height: 36px;
    position: absolute;
    left: -42px;
    top: -5px;
}

.reduction-text {
	font-family: 'Ubuntu', sans-serif;
    font-size: 22px;
    line-height: 23px;
    color: #AA212B;
    text-align: center;
    margin-top: 28px;
    font-weight: 700;
    margin-bottom: 2px;
}

.percentage-number {
    font-size: 36px;
     font-weight: 900;
}

.hr-text {
    color: #07729b;
    font-family: 'Ubuntu', sans-serif;
    line-height: 16px;
    text-align: center;
    font-size: 14px;
    margin-bottom: 6px;
    margin-top: 5px;
    font-weight: 500;
    letter-spacing: -0.42px;
}
.median-text {
    text-align: center;
    font-size: 11px;
    line-height: 14px;
    color: #555555;
    font-family: 'Ubuntu', sans-serif;
    font-weight: 500;
    margin-top: 0px;
}
.box-footnote{
    font-size: 12px;
    line-height: 14px;
    text-align: center;
    color: #555555;
    font-family: 'Ubuntu', sans-serif;
    margin-top: 29px;
    font-weight: 300;
}
.light-blue-reduction-text {
    font-family: 'Ubuntu', sans-serif;
    font-size: 22px;
    line-height: 25px;
    color: #07729b;
    text-align: center;
    margin-top: 28px;
    font-weight: 700;
    margin-bottom: 2px;
    letter-spacing: -0.77px;
}
span.fw-400 {
    font-weight: 500;
}
.light-blue-reduction-text span.fw-400 {
    font-size: 18px;
    line-height: 16px;
    display: block;
    font-weight: 600;
    letter-spacing: -0.54px;
}
.and-box-wrap {
    display: flex;
    align-items: center;
    justify-content: space-between;
    max-width: 428px;
    margin: 15px auto;
}
p.and-box-txt {
    font-family: "Ubuntu", sans-serif;
    font-weight: 700;
    font-size: 18px;
    letter-spacing: -0.42px;
    line-height: 18px;
    text-align: center;
}
.fw-reg {
    font-weight: 500;
}
.fw-light {
    font-weight: 400;
}
.blue-txt {
    color: #07729B;
}
p.and-box-txt .fw-light {
    font-size: 14px;
    color: inherit;
    line-height: 16px;
}
p.and-box-txt.white-txt {
    color: #fff;
    width: 33px;
    height: 33px;
    background: #07729B;
    display: flex;
    align-items: center;
    justify-content: center;
    font-weight: 300;
    border-radius: 50%;
    margin: 0 0 10px;
    font-size: 14px;
    line-height: 16px;
}
.light-blue-percentage-number {
    font-size: 36px;
    font-weight: 900;
    line-height: 16px;
    letter-spacing: -1.08px;
}
.median-text-light-blue,.updated-os-text {
    text-align: center;
    font-size: 12px;
    line-height: 14px;
    color: #555555;
    font-family: 'Ubuntu', sans-serif;
    font-weight: 500;
}

p.foot-text {
    font-size: 16px;
    line-height: 20px;
    text-align: center;
    color: #555555;
    max-width: 778px;
    margin: 0px auto 25px;
}

.updated-os-text{color: #003262;}
.arrow-image-text {
	font-size: 16px;
    font-family: 'Ubuntu', sans-serif;
    line-height: 20px;
    color: #555555;
    text-align: center;
    font-weight: 300;
}

.arrow-image-text img {
    width: 20px;
}

.data-bullet {
    margin: 0 7%;
    font-size: 16px;
    font-family: 'Ubuntu', sans-serif;
    line-height: 20px;
    color: #555555;
    font-weight: 300;
}

.data-bullet li::before {
    content: '';
    display: inline-block;
    height: 30px;
    width: 30px;
    background-image: url(/content/dam/website-services/us/434-imfinzi-com/dec-hcp/home/Dark%20Blue%20Arrow.png);
    background-repeat: no-repeat;
    background-position: bottom;
    background-size: 18px;
    margin-left: -31px;
}

.graph-container {
    text-align: center;
    margin-bottom: 20px;
}

.graph-image {
    width: 76%;
    margin: 0 auto;
 }
.graph-image-mobile {
    display: none;
    }
p.home-cta-sec {
    background: #07729b;
    text-align: center;
    color: #ffffff;
    margin: 20px auto 30px;
    font-size: 16px;
    line-height: 14px;
    font-weight: 700;
    padding: 14px 0;
    max-width: 600px;
    width: 599px;
    border: 1px solid #07729b;
    font-family: 'Ubuntu', sans-serif;
}
.cta-box a:hover {
    text-decoration: none;
}
p.home-cta-sec:after {
    content: '\f054';
    font-family: fontawesome;
    /* padding-left: 15px; */
    padding-left: 10px;
    font-weight: 100;
    position: relative;
    -webkit-text-stroke: 1px #07729b;
    speak: none;
    left: 6px;
    font-size: 18px;
    top: 2px;
}

p.home-cta-sec:after {
    content: "\f054" / "";
}

/*.pink-bracket {
    color: #FF00C4;
    }*/
p.home-cta-sec:hover {
    background: #ffffff;
    color: #003262;
}
.footnote-container{
    max-width: 1140px;
    margin: 35px auto;
    padding-bottom: 20px;
}

.footnote-container p {
    color: #FFFFFF;
    font-family: 'Ubuntu', sans-serif;
    font-size: 14px;
    line-height: 16px;
    font-weight: 400;
    letter-spacing: 0.2px;
 }
 .dmmr-endometrial-cancer-new .footnote-container p{
    letter-spacing: -0.1px;
    line-height: 17px;
    padding-right: 15px;
 }

 .study-design sup{
    font-size: 65%;
 }

.footnotes {
    text-indent: -5px;
 }

p.home-cta-sec br{
  display: none;
}
.reduction-text .percentage-number {
    position: relative;
    left: 3px;
}
.reduction-text sup.per-top, .light-blue-reduction-text sup.per-top{
    top: -0.8em;
    font-size: 16px;
}
.text-nowrap {
    white-space: nowrap;
}
p.study-design {
    margin-bottom: 30px;
}
.footnote-container {
    margin: 40px auto;
    padding-bottom: 30px;
}
.line-spacing-left {
    width: auto !important;
    max-width: 189px !important;
}
.line-spacing-right{
    max-width: 271px !important;
    width: auto !important;
}
.first-text-mobile { 
    display: none;
 }
 .red-dis-none-mobile {
    display: block;
    }
.red-dis-none-desktop {
    display: none;
    }
.nccn-sup {
   top: -0.4em;
}

.reference-section {
    padding-right: 10px;
}
/*body.efficacy.btc-hcp .reference-section {
    font-weight: 400;
    padding-right: 13px;
}

.break-work {
    word-break: break-all;
}*/

@media screen and (max-width: 991px){



	.imfinzi-durvalumab-resources.btc-hcp .navbar-nav > li > .dropdown-menu li a, 
	.imfinzi-durvalumab-resources.btc-hcp ul.nav.navbar-nav.navbar-right li.order-res-link ul.dropdown-menu.multi-level li a,
    .imfinzi-durvalumab-resources.btc-hcp ul.nav.navbar-nav.navbar-right li.order-res-link a:hover, 
	.imfinzi-durvalumab-resources.btc-hcp ul.nav.navbar-nav.navbar-right li.order-res-link.active a{
        background: none;
    }


    .btc-home-banner-bg {
        /*background: url(/content/dam/website-services/us/434-imfinzi-com/dec-hcp/home/Mobile%20Walker%20Art.png) no-repeat;*/
        background: url(/content/dam/website-services/us/434-imfinzi-com/dec-hcp/home/home-hero-image-mobile.png) no-repeat;
        background-size: 100%;
        background-color: #002440;
        background-position-y: -104px;
    }
    .btc-home-banner {
        margin: 0 auto;
        padding: 0px 0;
    }
    .home-heading h1 {
        line-height: 37px;
        text-align: center;
        margin: 59% auto 8%;
        padding: 0 10px;
        text-shadow: 1px 2px 2px #000000;
        font-size: 37px;
    }
    .btc-home-banner-bg h1.head-1 {
        font-size: 37px;
        line-height: 35px;
    }
    .head-1 sup {
        top: -9px;
        font-size: 64%;
    }
    .home-heading h1 > span:first-child {
        padding-left: 10%;
    	left: -2px;
    }
    .data-img-sec h3.head3 {
        font-size: 22px;
        line-height: 27px;
        margin: 10px 0 40px;
    }
    br.deskonly{
        display: none;
    }
    .home-heading h1 > span:last-child {
        padding-left: 0%;
    	margin-left: -23px;
    }
	.home-heading h1 span.wh-box {
        display: inline-block;
        margin: 12px 5px 0px 0px;
        padding: 0px 0;
        text-align: center;
        text-shadow: none;
        width: 78%;
        font-size: 13px;
        position: relative;
    	left: -67px;
	}
.heading-subh {
    /* margin-top:-75px; */
    margin-top: 160px;
    width: 89%;
    font-size: 20px;
    line-height: 22px;
    padding-top: 0;
}
.banner-data-sec {
    display: block;
    margin: 0 auto 0px;
    /* width: 100%; */
    justify-content: center;
    /* max-width: 1088px; */
}
.banner-data-sec > div {
    width: 103%;
}
.data-img-sec {
    padding: 5px 0px 40px;
}
.cta-box {
    margin-bottom: 20px;
}

.now-app-overlay {
    /*background: url(/content/dam/website-services/us/434-imfinzi-com/dec-hcp/home/Mask%20Group%203.png) no-repeat;*/
   /* background: url(/content/dam/website-services/us/434-imfinzi-com/dec-hcp/home/Desktop%20Violator%20blue%20shape.png) no-repeat;*/
    background: url(/content/dam/website-services/us/434-imfinzi-com/dec-hcp/dec-subpages/mobile/blue-angled-box-mobile.png) no-repeat;
    /*background-size: 100% 67%;*/
    background-size: 100% 100%;
    width: 375px;
    padding: 12px 0 14px 0;
    position: relative;
    top: 5px;
    left: -9px;
    display: inline-flex;
    align-items: center;
    /* height: 70px; */
    z-index: 2;
    transform: translateX(6px);
}

.now-app-overlay img {
    margin-left: 15px;
    margin-right: 8px;
    /* margin-top: -38px; */
    width: 53px;
    margin-top: 0;
}
.now-app-overlay p {
    font-size: 15px;
    line-height: 19px;
    /* margin-top: -38px; */
    max-width: 260px;
    margin-top: 0;
}
.now-app-overlay.now-app-overlay-2{
    background: url(/content/dam/website-services/us/434-imfinzi-com/dec-hcp/dec-subpages/mobile/red-angled-box-mobile.png) no-repeat;
    background-size: 100% 100%;
    max-width: 230px;
    top: -3px;
    padding: 11px 54px 30px 16px;
}
.now-app-overlay.now-app-overlay-2 p {
    font-size: 14px;
    line-height: 16px;
    text-align: left;
}
.callout-container {
    /*width: 100%;
    position: relative;
    display: inline-block;
    left: -3px;
    top: -93px;*/
    width: 100%;
    position: relative;
    display: inline-block;
    left: -4px;
    top: -101px;
}
.callout-open {
    background: url(/content/dam/website-services/us/434-imfinzi-com/dec-hcp/home/Mobile%20white%20bkgrd%20top.png) no-repeat content-box;
    background-size: 104% 100%;
    height: auto;
    position: relative;
    top: -1px;
    left: 0px;
    width: 101%;
    z-index: 1;
}
.callout-closed {
    background: url(/content/dam/website-services/us/434-imfinzi-com/dec-hcp/home/Mobile%20white%20bkgrd.png) no-repeat content-box;
    background-size: 103% 100%;
    height: 126px;
    position: absolute;
    top: -16px;
    width: 101%;
}
.down-image-closed {
    /*top: -51px;
    left: -8px;*/
    top: -24px;
    left: -22px;
    float: right;
    width: 25px;
    margin-left: 0;
}
.down-image-open {
    top: 24px;
    right: 14px;
    left: -24px;
    width: 25px;
}
.callout-closed p {
    padding-top: 53px;
    margin-left: 8px;
}
.nccn-heading {
    margin-left: 11px;
    position: relative;
    top: 8px;
}
.nccn-recommendation {
    font-size: 17px;
    top: 6px;
}
.nccn-category-bar {
    /*left: 17px;
    height: 129px;*/
    top: 76px;
    width: 96%;
    left: 2px;
}
.nccn-category-text::after { 
    /*top: 5px;*/
    margin-left: 10px;
}
.bar-footnote-container {
    margin-top: 85px;
    padding-left: 2px;
    padding-right: 11px;
    padding-bottom: 22px;
}
.bar-footnote{
    font-size: 12px;
    line-height: 14px;
    font-family: 'Ubuntu', sans-serif;
    font-weight: 400;
    text-indent: -5px;
    margin-bottom: 0px;
    }
.category-text {
    font-size: 13px;
    font-weight: 700;
}
.nccn-expanded-text {
    padding-top: 11px;
    padding-right: 2px;
    margin-left: -2px;
}
.nccn-category-text { 
    padding: 10px;
    padding-top: 40px;
}
.graph-image {
    display: none;
    }

.graph-image-mobile {
    display: block;
    width: 100%;
}
 .arrow-image-text {
    font-size: 16px;
    text-indent: -22px;
    width: 99%;
    text-align: left;
    margin-left: 10px;
    margin-right: auto;
}
.white-background {
    width: 96%;
    margin-top: 32px;
}
p.home-cta-sec {
    width: 86%;
    font-size: 14px;
    margin: 0px auto 0px;
    line-height: 16px;
    padding: 21px 0;
}
p.home-cta-sec:after {
    padding-left: 5px;
    top: -11px;
    left: 11px;
}
p.safety-cta{
	margin-top: 23px;
    height: 65px;
    padding: 20px 0;
}
p.home-cta-sec:after {
    top: 2px;
    left: 12px;
}
p.home-cta-sec br{
  display: block;
}

.footnote-container {
    padding-left: 24px;
    padding-right: 24px;
    margin: 30px auto;
    padding-bottom: 22px;
}
.box-footnote {
	margin-top: 20px;
    max-width: 275px;
    margin: 14px auto;
}
p.study-design {
    margin-bottom: 30px;
    font-weight: 700;
}
.footnote-container p{
    font-weight: 500;
}
.median-text br {
     display: none;
 }
.white-background .first-text { 
    display: none;
}
.first-text-mobile { 
    display: block;
    width: 100%;
    font-size: 16px;
    line-height: 18px;
    font-family: 'Ubuntu', sans-serif;
    text-align: center;
    margin-bottom: 0px;
    color: #003262;
}
.median-text {
    font-size: 12px;
    }
.reduction-text {
    width: 95%;
    margin-top: 16px;
 }
.reduction-text br {
    display: none;
 }
.reduction-text { 
    font-size: 22.5px;
}
.banner-data-right {
    margin-top: -23px;
}
.banner-data-third { 
    margin-top: -11px;
}
.banner-data-third .arrow-box {
    width: 102%;
}
.light-blue-reduction-text {
   margin-top: 18px;
    width: 100%;
    margin-left: auto;
    margin-right: auto;
}
h2.box-heading:before {
    width: 38px;
    height: 23px;
    left: -23px;
    top: 4px;
}
.box-heading-light-blue:before {
    background-size: 100%;
    width: 41px;
    height: 26px;
    left: -22px;
    top: -2px;
}
.box-image { 
   padding: 20px 15px 5px 15px !important;
}
.box-image-light-blue { 
    padding: 20px 5px 0px 5px !important;
}
h2.box-heading { 
    padding: 0px 6px 0 13px;
    margin-top: -36px;
}
.box-heading-light-blue { 
    font-size: 16px;
    line-height: 18px;
    padding: 1px 6px 5px 28px;
    /* margin-top: -47px; */
    max-width: 279px;
}
p.and-box-txt{
    font-size: 15px;
    line-height: 14px;
}
p.and-box-txt .fw-light {
    font-size: 10px;
    line-height: 14px;
}
p.and-box-txt.white-txt{
    width: 20px;
    height: 20px;
    font-size: 9px;
    line-height: 9px;
}
.and-box-wrap{
    margin: 14px auto 15px;
    max-width: 270px;
}
p.foot-text{
    max-width: 280px;
    margin: 0px auto 20px;
}
.dmmr-endometrial-cancer-new .footnote-container p {
    letter-spacing: -0.1px;
}
.red-dis-none-mobile {
    display: none;
    }
.red-dis-none-desktop { 
    display: block;
    font-size: 21.5px;
}
.nccn-expanded-text p {
    margin-left: 10px;
    font-size: 12px;
 }
    .data-bullet {
        margin: 0 0;
    	padding-bottom: 13px;
    }

    /*body.efficacy.btc-hcp .reference-section {
        padding-right: 9px;
    }*/

}

@media screen and (min-width: 820px) and (max-width: 1180px){
    .home-heading h1 > span:first-child {
    	padding-left: 21%;
    }
    .home-heading h1 > span:last-child {
	    margin-left: 34px;
        position: relative;
    	left: -10px;
	}
    .home-heading h1 span.wh-box {
        width: 60%;
    }
}
@media screen and (min-width: 820px) and (max-width: 1180px) and (orientation: landscape){
    .nccn-heading {
    	font-size: 19px;
    }
    .callout-closed {
     	height: 71px;
     }
    .callout-closed p {
        margin-left: 24px;
    }
    .nccn-recommendation {
    	font-size: 14px;
     }
     .down-image-closed {
        margin-left: 11px;
        top: -1px;
        left: -8px;
    }
    .home-heading h1 {
    	font-size: 56px;
     }
     .home-heading h1 > span:first-child {
    	padding-left: 6%;
       	left: 0px;
	}
    .home-heading h1 span.wh-box {
        width: 96%;
        left: -3px;
        position: relative;
        font-size: 20px;
    }
}

@media screen and (min-width: 768px) and (max-width: 1024px){
    .callout-container {
    	width: 97%;
    }
    .callout-open {
        height: auto;
    }
	.nccn-category-bar {
    	top: 61px;
        /* height: 85px; */
        width: 97%;
    }
    .bar-footnote-container { 
    	margin-top: 75px;
    	padding-bottom: 17px;
    	padding-left: 5px;
    }
    .nccn-category-text::after {
        height: 65px;
    }
    .nccn-category-text {
        padding-top: 21px;
    }
    .nccn-expanded-text{
    	padding-top: 23px;
    }
    .callout-closed{
        height: 126px;
        width: 101%;
    }
    .callout-closed p { 
        padding-top: 63px;
	}
	.now-app-overlay {
    	height: 85px;
	} 
    /*.now-app-overlay img {
    	margin-top: 5px;
     }
     .now-app-overlay p {
        margin-top: 6px;
     }*/
     .down-image-closed {
        top: -24px;
        left: -21px;
        float: right;
    }
    .down-image-open {
    	top: 35px;
    	left: -27px;
    }
    .first-text-mobile {
        display: none;
    }
    .first-text {
       	display: block!important;
     }
	.banner-data-sec > div {
    	width: 100%;
	}
	.banner-data-sec .data-img-sec {
 	   max-width: 767px;
	}
	.box-footnote {
    	max-width: fit-content;
    }
    .arrow-image-text {
    	text-indent: 0px;
    }
    .banner-data-third .arrow-box {
 		width: 90%;
    	margin: 0 auto;
	}
	.home-heading h1 > span:first-child {
    	padding-left: 21%;
	}
	.home-heading h1 span.wh-box {
    	width: 60%;
        left: -101px;
    }
	.home-heading h1 > span:last-child {
        padding-left: 0%;
        margin-left: -23px;
        position: relative;
        left: -31px;
	}
}

/*@media screen and (min-width: 1536px) */
@media screen and (min-width: 1517px){
	.home-heading h1 {
    	padding: 18% 0 17%;
     }
    .callout-closed p {
    	padding-top: 20px;
        margin-left: 62px;
	}
    .down-image-closed {
        top: 11px;
    	left: -15px;
    	float: right;
    	width: 30px;
    }
	.down-image-open {
    	width: 30px;
    }
}

/*@media screen and (max-width: 1152px){
	.callout-open {
        height: 361px;
     }
    .nccn-category-bar {
        height: 141px;
     }
     .nccn-expanded-text {
        padding-top: 6px;
    }
    .nccn-category-text {
        padding-top: 42px;
    }
    .nccn-category-text::after{
         height: 116px;
    }
}*/

@media screen and (min-width: 1200px) and (max-width: 1365px){
    /*.now-app-overlay {
        width: 78.9%;
    }*/
    .callout-container {
        width: 27%;
    }
	.nccn-closed-image {
        float: right;
     }
    .callout-closed {
        height: 77px;
    }
    .home-heading h1 {
        font-size: 54px;
    }
    .home-heading h1 > span:last-child {
        padding-left: 6%;
        position: relative;
        left: -11px;
	}
    .home-heading h1 span.wh-box {
        width: 97%;
    	font-size: 19px;
     }
    .callout-open {
        height: auto;
    }
	.callout-closed p {
    	padding-top: 24px;
    	margin-left: 25px;
    }
	.nccn-heading {
    	font-size: 26px;
    }
    .down-image-closed {
        top: -27px;
        left: -3px;
        width: 17px
    }
	/*.nccn-expanded-text {
        padding-top: 9px;
	}*/
	.down-image-open {
    	left: -8px;
    	top: 33px;
    	width: 17px;
    }
	.nccn-heading::after {
    	left: -4px;
    }
    .nccn-recommendation {
        left: 0px;
     }
}

/*@media screen and (min-width: 1366px) and (max-width: 1500px){
.home-heading h1 span.wh-box {
    width: 258px;
}
}*/

@media screen and (min-width: 992px){
	/*.about-btcs .about-btcs-sec .page-content > h2:nth-child(1) {
        width: 101%;
    }

    .efficacy.btc-hcp h2#eff-head-1 + .box-image .reduction-text {
        width: 102%;
        margin-left: -1.5%;
    }*/

    .cta-box{
	display: flex;
    justify-content: space-around;
        }
}

@media screen and (min-width: 992px) and (max-width: 1199px){
	.now-app-overlay img {
    	margin-left: 2px;
	}
    .home-heading h1 > span:first-child {
    	padding-left: 14%;
	}
    .home-heading h1 > span:last-child {
        margin-left: 15px;
        position: relative;
        left: -49px;
	}
    .home-heading h1 {
    	font-size: 50px;
	}
    .home-heading h1 span.wh-box {
        width: 98%;
        left: -4px;
        font-size: 18px;
    }
	.nccn-category-bar {
        top: 49px;
        height: auto;
        width: 95%;
    }
	.nccn-category-text {
        padding: 6px;
    	padding-top: 39px;
    }
    .nccn-expanded-text p {
    	/*margin-left: 3px;*/
    	font-size: 9px;
     }
	/*.nccn-expanded-text {
        padding-top: 3px;
    }*/
	.nccn-category-text::after {
        height: 104px;
    }
	.bar-footnote-container {
        margin-top: 55px;
    	padding-left: 0px;
    	padding-right: 5px;
    	padding-bottom: 19px;
    }
	/*.callout-open {
        height: 301px;
    }*/
	.down-image-open {
        top: 31px;
        left: -6px;
        width: 17px;
    }
	.callout-closed {
        height: 80px;
        width: 100%;
    }
	.callout-closed p {
        padding-top: 16px;
    }
	.nccn-recommendation {
        font-size: 11px;
    }
	.down-image-closed {
        top: 14px;
    	left: -6px;
        float: right;
        width: 17px;
    }
	.bar-footnote {
   		line-height: 11px;
    }
}
@media screen and (min-width: 992px) and (max-width: 995px){
    .down-image-closed {
        top: -18px;
        left: -5px;
    }
}
@media screen and (min-width: 1233px) and (max-width: 1365px){
    .down-image-closed {
        top: 4px;
        left: -12px;
    	width: 22px;
     }
    .down-image-open {
        left: -12px;
        top: 31px;
        width: 22px;
    }
    .callout-closed p {
        padding-top: 24px;
        margin-left: 20px;
	}
}
@media screen and (min-width: 449px) and (max-width: 767px){
	/* .now-app-overlay {
        background-size: 100% 72%;
     } */
}
@media screen and (min-width: 1920px){
    .now-app-overlay {
        width: 72.5%;
     }
	.callout-container {
        width: 31%;
     }
    /*.nccn-category-bar {
        left: 27px;
     }*/
    .home-heading h1 {
    	padding: 33% 0 17%;
	}
    .callout-closed {
     	height: 77px;
        background-position-x: -3px;
    }
    .nccn-expanded-text {
    	padding-top: 32px;
    }
    .bar-footnote-container {
        padding-left: 18px;
        padding-right: 18px;
    }
  	.nccn-heading::after {
        margin-left: 10px;
        margin-right: 10px;
    }
}
@media screen and (min-width: 1440px) and (max-width: 1516px){
    .down-image-closed {
    	top: -3px;
    	left: 5px;
     }
    .callout-closed p {
        margin-left: 40px;
     }
}
@media screen and (min-width: 1882px) and (max-width: 1919px){
	.callout-container {
    	width: 28%;
    }
    .now-app-overlay {
        background-size: 101% 127%;
     }
}
@media screen and (min-width: 2048px){
    .callout-container {
    	width: 33.5%;
	}
}