@import url('https://fonts.googleapis.com/css2?family=Ubuntu:ital,wght@0,400;0,700;1,400;1,700&display=swap');
@import url('https://fonts.googleapis.com/css2?family=Ubuntu+Sans:ital,wght@0,100..800;1,100..800&display=swap');

@font-face {
    font-family: 'Karbon';
    src: url('/etc/designs/code/website-services/us/imfinzi-com/fonts/Karbon-Regular.woff') format('woff');
    font-weight: normal;
    font-style: normal;
    font-display: swap;
}
@font-face {
    font-family: 'Karbon-Bold';
    src: url('/etc/designs/code/website-services/us/imfinzi-com/fonts/Karbon-Bold.woff') format('woff');
    font-weight: bold;
    font-style: normal;
    font-display: swap;
}
@font-face {
    font-family: 'Karbon-Medium';
    src: url('/etc/designs/code/website-services/us/imfinzi-com/fonts/Karbon-Medium.woff') format('woff');
    font-weight: 500;
    font-style: normal;
    font-display: swap;
}


/* body.efficacy.bc-mi  .page-content {
    background-image: none;
    background-color: #fff;
}
.header-iparsys.iparsys.parsys{
	display:none;
}
.sticky-isi-wrapper {
    display: none !important;
} */
.pinkBracket{
	color: #FF009D;
    display: none;
}

.superscript-text {
    font-size: 71%;
    top: -.6em !important;
    font-family: Arial;
}

.tbl-baseline-char b{
	font-weight:700!important;
        font-family: 'Karbon-Bold';
}
.backGroundWhite{
	max-width: 888px;
    margin: 0 auto;
    background: #fff;
    padding-bottom:35px;
}

.backGroundWhite.noBottomPadding{
	padding-bottom:0;
}
.content-box.content-box--bullet sup {
    top: -.3em;
}
sup.sup12 {
    font-size: 10px;
    top:-5.4px !important;
}
.bc-mi main#maincontent {
        background: linear-gradient(180deg, rgba(228, 237, 252, 0.00) 0%, #E4EDFC 100%);
    }
.bc-mi .reference-section-width a {
	word-break: initial;
}
.txtIndent{
	text-indent: -6px;
}

.doubleTxtIndent{
	text-indent: -9px;
}

.efficacy.bc-mi .page-content .headline-var__eyebrow {
    color: #003262;
    font-family: Ubuntu;
    font-size: 16px;
    font-style: normal;
    font-weight: 400;
    line-height: normal;
    /*margin: 30px 0 10px;*/
    padding: 30px 0 10px;
}

.efficacy.bc-mi .page-content h2.headline-var {
    font-family: Ubuntu;
    font-size: 24px;
    font-style: normal;
    font-weight: 500;
    /*font-weight: 600;*/
    line-height: normal;
    color: #003865;
    margin: 0;
}
h2.headline-var.headline-var1 sup {
    top: -0.28em;
}
sup.adv-eve {
    font-size: 14px;
    top: 0em;
}
.efficacy.bc-mi .page-content h2.headline-var.timeToRC{
	padding-top:0!important;
    font-weight:400!important;
}

.efficacy.bc-mi span.headline-var--red {
    color: #AC182E;
    font-weight: 700;
    /*font-weight: 500;*/
}

.efficacy.bc-mi .content-box.content-box--two-col {
    padding: 30px 35px 20px 35px;
    margin: 35px auto 35px;
}

.efficacy.bc-mi .content-box--two-col__wrapper {
    display: flex;
    gap: 14px;
    align-items: center;
}

.efficacy.bc-mi span.content-box--two-col__copy--headline {
    font-size: 24px;
    font-weight: 700;
    line-height: 22px;
    display: block;
    margin: 5px 0 5px;
}

.efficacy.bc-mi  .content-box--two-col__image {
    margin: 0 0 0 5px;
}

.efficacy.bc-mi .content-box--two-col__copy p {
    color: #003865;
    font-family: Ubuntu;
    font-size: 16px;
    font-style: normal;
    /*font-weight: 600;*/
    font-weight: 500;
    line-height: 22px;
    margin: 0 0 5px;
}

.efficacy.bc-mi  p.content-box--two-col__copy--disclaimer {
    color:  #555;
    font-weight: 400;
    line-height: 19px;
}

.efficacy.bc-mi .content-box--two-col__footnote p {
    color: #555;
    font-family: Ubuntu;
    font-size: 11px;
    font-style: normal;
    font-weight: 400;
    line-height: 12px;
    margin: 25px 0 0;
}

.efficacy.bc-mi .page-content .headline-var--sub {
    color:  #003865;
    font-family: Ubuntu;
    font-size: 20px;
    font-style: normal;
   /* font-weight: 600;*/
    font-weight:500;
    line-height: normal;
}

.efficacy.bc-mi .headline-var__disclaimer p {
    color:  #555;
    font-family: Ubuntu;
    font-size: 16px;
    font-style: normal;
    font-weight: 700;
    line-height: normal;
    margin: 20px 0 30px;
}

.efficacy.bc-mi .event-free .page-content  ul.list {
    margin: 27px 0 35px;
}

.efficacy.bc-mi .event-free .page-content .headline-var--sub {
    margin: 0 0 40px;
}

.efficacy.bc-mi .footnote.footnote--content-page {
    margin: 30px 0 0;
    padding-bottom: 35px
}
.efficacy.bc-mi .footnote.footnote--content-page.pb0 {
    padding-bottom: 0;
	margin-left: 10px;
}
.efficacy.bc-mi .footnote.footnote--content-page p {
    color: #555;
    font-family: Ubuntu;
    font-size: 12px;
    font-style: normal;
    font-weight: 400;
    line-height: 14px;
    display: block;
    text-indent: -4px;
    padding-left: 4px;
}
.footnote.footnote--content-page.ftnt-baseline.pb0 p {
    text-indent: -12px !important;
    padding-right: 4px;
    padding-left: 0;
}
.footnote.footnote--content-page.ftnt-baseline.pb0 p.doubleTxtIndent {
    text-indent: -10px !important;
}
.efficacy.bc-mi .footnote.footnote--content-page p:first-child {
    /*padding-bottom: 4px;*/
}
.efficacy.bc-mi .footnote.footnote--content-page p:second-child {
    padding-bottom: 4px;
}
.footnote.footnote--content-page.ftnote-sd p:first-child {
    margin-left: -1px !important;
}
.footnote.footnote--content-page.ftnote-sd {
    padding-bottom: 0 !important;
}
.efficacy.bc-mi .content-box.content-box--bullet ul.list {
    margin: 5px 0;
    font-family: Ubuntu;
}

.efficacy.bc-mi p.list__footnote {
    color: #555;
    font-family: Ubuntu;
    font-size: 13px;
    font-style: normal;
    font-weight: 400;
    line-height: 15px;
    margin: 20px 0 10px;
    padding: 0 15px;
    display: flex;
}

sup.special-dagger {
    font-family: sans-serif;
}

.efficacy.bc-mi p.list__footnote sup {
    top: 4px;
    font-family: 'Ubuntu', sans-serif;
}

.efficacy.bc-mi .content-box.content-box--bullet {
    margin: 0 0 35px;
}

.efficacy.bc-mi .overall-surv .content-box.content-box--two-col {
    margin: 35px auto 40px;
}

.efficacy.bc-mi .overall-surv .content-box--two-col__footnote p {
    margin: 10px 0 0;
}

.efficacy.bc-mi .overall-surv .content-box.content-box--two-col {
    margin: 35px auto 40px;
}

.efficacy.bc-mi .overall-surv .page-content  ul.list {
    margin: 27px 0 25px;
}

.efficacy.bc-mi .overall-surv .page-content h3.headline-var--sub {
    margin: 0 0 55px;
    font-weight: 400;
}

/*.table-block.sf-ar-1.new-table.tbl-baseline-char.content-box-image--wrapper sup {
    font-size: 60%;
}*/

.efficacy.bc-mi .overall-surv .page-content h3.estimatedOS sup .dagger-sym {
    font-size: 90%;
}


.efficacy.bc-mi .overall-surv .page-content h3.estimatedOS {
	margin: 40px 0 30px;
}

.efficacy.bc-mi .overall-surv .page-content h3.osData {
    font-weight: 500;
}

.overall-surv .headline-var__disclaimer p {
    margin: 20px 0 35px;
}

.efficacy.bc-mi .page-content-head {
    background: #fff;
    max-width: 888px;
    margin: 0 auto;
}

.overall-surv .page-content-head {
    padding-top: 35px;
}
.efficacy.bc-mi .page-content {
    background: #fff;
    /*max-width: 773px;*/
    margin: 0 auto!important;
}
.efficacy.bc-mi .page-heading h1 {
    font-family: 'Ubuntu', sans-serif;
    font-size: 58.6px;
    font-style: normal;
    font-weight: 700;
    line-height: normal;
    text-transform: uppercase;
    color: #003865;
    padding: 20px 0px 35px 0px;
    margin: 0 auto!important;
}

.event-free{
	max-width: 888px;
    margin: 0 auto;
    background: #fff;
}

.efficacy.bc-mi .section-heading {
    border-top: 1px solid #003865;
}
.efficacy.bc-mi .section-heading p {
        padding-top: 9px;
        padding-left: 55px;
        color: #FFF;
        font-family: Ubuntu;
        font-size: 18px;
        font-style: normal;
        font-weight: 700;
    	margin: 0 auto;
}
.efficacy.bc-mi .section-heading span {
    color: #ffffff;
    background: #07729B;
    font-size: 18px;
    line-height: normal;
    font-weight: 700;
    padding: 11px 25px;
    border-bottom-left-radius: 16px;
    border-bottom-right-radius: 16px;
    font-family: 'Ubuntu', sans-serif;
}
.efficacy.bc-mi .page-content h2 {
    font-family: 'Ubuntu', sans-serif;
    font-size: 24px;
    font-style: normal;
    font-weight: 700;
    line-height: normal;
    margin: 33px 0 10px;
    color: #003865;
}

.efficacy.bc-mi .content-box {
    border: 1px solid #03315D;
    border-left: 10px solid #03315D;
    border-bottom-right-radius: 32px;
    padding: 15px;
    position: relative;
}
/*.content-box.content-box-efs:after {
    color: rgba(255, 0, 255, 0.60);
    font-family: 'Roboto';
    font-size: 110px;
    font-style: normal;
    font-weight: 700;
    line-height: normal;
    content: 'FPO';
    position: absolute;
    transform: rotate(-26.95deg);
    left: 35%;
    top: 35%;
} */
/* .table-block.sf-ar-1.new-table.tbl-baseline-char.content-box-image--wrapper:after {
    color: rgba(255, 0, 255, 0.60);
    font-family: 'Roboto';
    font-size: 110px;
    font-style: normal;
    font-weight: 700;
    line-height: normal;
    content: 'FPO';
    position: absolute;
    transform: rotate(-26.95deg);
    left: 35%;
    top: 35%;
} */
.efficacy.bc-mi .content-box .box-title {
    font-family: 'Ubuntu', sans-serif;
    font-size: 14px;
    font-style: normal;
    font-weight: 700;
    line-height: 22px;
    /* text-transform: uppercase; */
    color: #003865;
    margin: 0;
    position: absolute;
    top: -18px;
    left: 0px;
    background: #fff;
    padding: 0 10px 0 15px;
        z-index: 2;
}
.content-box-image--wrapper img.mobile-only1.hand-icon {
    display: none;
}
.efficacy.bc-mi .content-box .box-title::before {
    content: '';
    background: #03315d;
    position: absolute;
    left: -10px;
    top: 3px;
    width: 10px;
    height: 15px;
}

.table-block.mobile-only .mobile-only1.hand-icon{
	position: absolute;
    top: 50%;
    left: 50%;
}

.scroll-indicator.mobile-only.EFS{
	/*display:none;*/
}

.efficacy.bc-mi .content-box.content-box--callout {
    border-color: #AC182E;
    margin: 20px auto 20px;
}

.efficacy.bc-mi .callout-content p {
    color: #AC182E;
    font-family: "Ubuntu Sans", serif;
    font-size: 18px;
    font-style: normal;
    font-weight: 700;
    line-height: normal;
    margin: 0;
}

.efficacy.bc-mi .callout-content {
    display: flex;
    align-items: center;
    justify-content: normal;
}

.efficacy.bc-mi .footnote {
    margin: 25px 0 3px;
}
.efficacy.bc-mi .footnote p {
    font-family: 'Ubuntu', sans-serif;
    font-size: 12px;
    font-style: normal;
    font-weight: 400;
    line-height: 14px;
    margin: 0;
    color: #555;
    display: flex;
    align-items: center;
    gap: 1px;
}

.efficacy.bc-mi .page-content  ul.list {
    padding: 0 0 0 24px;
    margin: 27px 0;
}
.efficacy.bc-mi .page-content  .list li {
    font-family: 'Ubuntu', sans-serif;
    font-size: 16px;
    font-style: normal;
    font-weight: 400;
    line-height: normal;
    margin: 0 0 6px;
    color: #555;
}
.efficacy.bc-mi .page-content  .list li:before {
    left: -15px;
    line-height: normal;
    content: url(/content/dam/website-services/us/434-imfinzi-com/hcp-bc-mi/Global/bullet-marker.svg);
    width: 6px;
    height: 6px;
    display: inline-block;
    font-size: 16px;
    top: 3px;
}
.efficacy.bc-mi .page-content  .list ul.list-sub li:before {
    content: "•";
    left: -5px;
}
.efficacy.bc-mi .page-content  .list li ul {
    padding: 4px 23px 0 25px;
}

.efficacy.bc-mi .page-content  .list li ul li:before {
    color: #555555;
    left: -10px;
    line-height: normal;
}

.efficacy.bc-mi .page-content  .content-cta {
    border-bottom-right-radius: 22px;
    padding: 12px 15px;
    background: #07729B;
    margin: 45px auto 35px;
    max-width: 451px;
    height: 42px;
    display: flex;
    justify-content: center;
    align-items: center;
}
.efficacy.bc-mi .page-content  .content-cta--link {
    color: #FFF;
    text-align: center;
    font-family: Ubuntu;
    font-size: 18px;
    font-style: normal;
    font-weight: 700;
    line-height: 18px;
}

.efficacy.bc-mi .content-box > img {
    margin: 0 0 5px;
    width: 100%;
}

.efficacy.bc-mi .overall-surv {
   /* margin: 0 0 50px;*/
}

.page-content-switch {
    max-width: 720px;
    margin: 35px auto 57px;
}

.switch-section {
    display: flex;
    justify-content: space-between;
    padding-left: 4px;
    padding-right: 29px;
}

.switch-section a {
    font-family: 'Ubuntu', sans-serif;
    font-size: 16px;
    font-style: normal;
    font-weight: 700;
    line-height: normal;
    color: #003865;
}


.switch-section a:first-child {
    background-image: url(/content/dam/website-services/us/434-imfinzi-com/hcp-bc-mi/Global/nav-back.svg);
    background-repeat: no-repeat;
    background-position: left;
    background-size: 20px;
    padding-left: 24px;
    height: 20px;
}

.switch-section a:last-child {
    background-image: url(/content/dam/website-services/us/434-imfinzi-com/hcp-bc-mi/Global/nav-next.svg);
    background-repeat: no-repeat;
    background-position: right;
    background-size: 20px;
    padding-right: 24px;
    height: 20px;
}

.efficacy.bc-mi .overall-surv.surgical-data .section-heading p{
    margin: 0;
    padding-top: 0;
}

.efficacy.bc-mi .overall-surv.surgical-data .section-heading p span{
    display: inline-block;
}

.efficacy.bc-mi .overall-surv.surgical-data .page-content h2 {
    /*margin: 32px 0 34px 0;*/
    margin: 0;
    font-weight: 500;
    padding: 32px 0 34px;
}
/*.efficacy.bc-mi .overall-surv.surgical-data .page-content p{
    color: #000;font-family: 'Ubuntu';font-size: 20px;font-style: normal;font-weight: 500;
    line-height: normal;padding: 0 60px 0 0;margin: 0 0 30px 0;
}*/

.efficacy.bc-mi .overall-surv.surgical-data .page-content p.box-title {
    font-family: 'Ubuntu', sans-serif;
    font-size: 14px;
    font-style: normal;
    font-weight: 700;
    line-height: 22px;
    color: #003865;
    margin: 0;
    position: absolute;
    top: -14px;
    left: 0px;
    background: #fff;
    padding: 0 10px 0 15px;
}

.efficacy.bc-mi .overall-surv.surgical-data .content-box--two-col__wrapper-II {
    display:flex;
    justify-content: center;
    gap: 200px;
}

.efficacy.bc-mi .overall-surv.surgical-data .content-box {
    padding: 20px 0;
    margin: 0 0 50px 0;
}

.efficacy.bc-mi .overall-surv.surgical-data .content-box.completing-table {
    padding: 34px 22px 16px 17px;
}

.efficacy.bc-mi .overall-surv.surgical-data .content-box--two-col__wrapper-II .content-box--two-col__image {
    width: 129px;
    margin: 0;
}

.efficacy.bc-mi .overall-surv.surgical-data .content-box--two-col__wrapper-II .content-box--two-col__image img {
    width: 100%;
}

.overall-surv.surgical-data table {
    border-collapse: collapse;
    border-spacing: 0;
    width: 100%;
    margin: 0 auto;
}
.overall-surv.surgical-data td:first-child, .overall-surv.surgical-data th:first-child {
    text-align: left;
    border-left: none;
    color: #4D4D4F;
    max-width: 260px;
}
.overall-surv.surgical-data td, .overall-surv.surgical-data th {
    padding: 4px 10px;
    font-size: 12px;
    border: 0.25px solid #c6c6c8;
    text-align: center;
    font-family: 'Karbon';
    max-width: 223px;
}
.overall-surv.surgical-data .table-block {
    margin: 0 0 16px 0;
    position: relative;
}
.overall-surv.surgical-data .table-block.new-table table tr:nth-child(1) th:nth-child(1) {
    width: 299px;
    font: normal normal 700 14px / 16px 'Ubuntu', sans-serif;
}

.overall-surv.surgical-data .table-block.new-table table tr:nth-child(1) th:nth-child(1), .overall-surv.surgical-data .table-block.new-table table tr:nth-child(1) th:nth-child(2) {
    border-top: none;
    /* border-right: 1px solid #707070;*/
}
.overall-surv.surgical-data .table-block.new-table table tr:nth-child(1) th:nth-child(2) {
    background: #f1f5fa;
    font-family: 'Karbon-Bold';
}
.overall-surv.surgical-data .table-block.new-table table tr:nth-child(1) th:nth-child(1), .overall-surv.surgical-data .table-block.new-table table tr:nth-child(1) th:nth-child(3) {
    border-bottom: none;
    border-top: none;
    border-right: none;
}
.overall-surv.surgical-data .table-block.new-table table tr td:nth-child(3) {
    border-right: none;
}
.overall-surv.surgical-data .table-block table tr:nth-child(1) th:nth-child(2) {
    color: #c0403a;
    background: none;
}
.overall-surv.surgical-data td:nth-child(2) {
    color: #AC1F2F;
    font-size: 11px;
    font-style: normal;
    font-weight: 700;
    line-height: normal;
    background: #F1F5FA;
    font-family: 'Karbon-Bold';
}
.overall-surv.surgical-data td:nth-child(3) {
    color: #4D4D4F;
    font-size: 11px;
    font-style: normal;
    font-weight: 400;
    line-height: normal;
}
.paitent-decision-block {
    width: 144px;
    position: absolute;
    right: 150px;
    top: 46px;
    border: 1px solid #003262;
    background: #FFF;
    padding: 4px 0;
}
.efficacy.bc-mi .overall-surv.surgical-data .page-content .paitent-decision-block p {
    color: #00355F;
    font-family: Karbon;
    font-size: 13px;
    font-style: normal;
    font-weight: 400;
    line-height: normal;
    padding: 0;
    margin: 0;
    text-align: center;
}
.efficacy.bc-mi .overall-surv.surgical-data .page-content .paitent-decision-block p strong {
    font-family: 'Karbon-Bold';
}
.paitent-decision-block::before {
    content: '';
    width: 0;
    height: 0;
    border-style: solid;
    border-top: 10px solid transparent;
    border-bottom: 10px solid transparent;
    border-left: 10px solid #003262;
    border-right: 0;
    position: absolute;
    right: -11px;
    top: 15px;
}
.paitent-decision-block::after {
    content: '';
    width: 0;
    height: 0;
    border-style: solid;
    border-top: 10px solid transparent;
    border-bottom: 10px solid transparent;
    border-left: 0;
    border-right: 10px solid #003262;
    position: absolute;
    left: -11px;
    top: 15px;
}


/* basline-char-table */
.table-block.sf-ar-1.new-table.tbl-baseline-char th, .table-block.sf-ar-1.new-table.tbl-baseline-char td {
    padding: 2px 10px;
    font-size: 13.5px !important;
    border: 1px solid #c6c6c8;
    text-align: center;
    font-family: 'Karbon';
    color: #4D4D4F;
}
.table-block.sf-ar-1.new-table.tbl-baseline-char th:first-child, .table-block.sf-ar-1.new-table.tbl-baseline-char td:first-child {
    text-align: left;
}
tr.td-sub td:first-child {
    padding-left: 30px !important;
}
tr.td-sub td:first-child b {
    margin-left: -20px;
}
.table-block.sf-ar-1.new-table.tbl-baseline-char th:nth-child(2), .table-block.sf-ar-1.new-table.tbl-baseline-char td:nth-child(2) {
    font-family: 'Karbon-Bold';
    background: #F1F5FA;
}
.table-block.sf-ar-1.new-table.tbl-baseline-char table tr:nth-child(1) th:nth-child(1), .table-block.sf-ar-1.new-table.tbl-baseline-char table tr:nth-child(1) th:nth-child(2), .table-block.sf-ar-1.new-table.tbl-baseline-char table tr:nth-child(1) th:nth-child(3) {
    border-bottom: none;
    border-top: none;
    border-right: none;
}
.table-block.sf-ar-1.new-table.tbl-baseline-char th:first-child, .table-block.sf-ar-1.new-table.tbl-baseline-char td:first-child {
    border-left: none;
    width: 230px;
}
.table-block.sf-ar-1.new-table.tbl-baseline-char tr td:nth-child(3) {
    border-right: none;
}

.paitent-treated-block {
    width: 161px;
    position: absolute;
    right: 175px;
    top: 400px;
    border: 1px solid #003262;
    background: #FFF;
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}

span.special-sym {
    font-family: Helvetica, Arial, sans-serif;
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    font-size: 12.5px;
}

span.special-sym2 {
    font-family: Helvetica, Arial, sans-serif;
    margin: 0 1px 0 0;
    font-size: 12.5px;
}

.paitent-treated-block p {
    color: #00355F;
    font-family: 'Karbon';
    font-size: 13.5px;
    font-style: normal;
    font-weight: 400;
    line-height: normal;
    padding: 0;
    margin: 0;
    text-align: center;
}
.paitent-treated-block::after {
    content: '';
    width: 0;
    height: 0;
    border-style: solid;
    border-top: 12px solid transparent;
    border-bottom: 12px solid transparent;
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    border-right: 12px solid #003262;
    position: absolute;
    left: -13px;
    top: 25px;
}
.paitent-treated-block.pt2 {
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    padding: 6.5px 5px;
}
.paitent-treated-block.pt3 {
    top: 591px;
    padding: 6.5px 5px;
}
.paitent-treated-block.pt3::after{
    top: 30px;
}
/*::-webkit-scrollbar { 
    display: none; 
}*/



.efficacy.bc-mi .overall-surv.surgical-data .content-box.completing-table img {
    margin: 0;
}

.efficacy.bc-mi .overall-surv.surgical-data .footnote.footnote--content-page p {
    color: #555;
    font-family: Ubuntu;
    font-size: 12px;
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    font-weight: 400;
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}

.efficacy.bc-mi .overall-surv.Study-desing-wrap .footnote.footnote--content-page p {
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.efficacy.bc-mi .overall-surv.surgical-data .page-content .red-box-wrap {
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    border-bottom-right-radius: 32px;
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.efficacy.bc-mi .overall-surv.surgical-data .page-content .red-box-wrap p {
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.efficacy.bc-mi .overall-surv.Study-desing-wrap .section-heading p{
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    padding-top: 0;
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.efficacy.bc-mi .overall-surv.Study-desing-wrap .section-heading p span{
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.efficacy.bc-mi .overall-surv.Study-desing-wrap .page-content h2.headline-var{
    margin: 36px 0 16px 0;
}

.efficacy.bc-mi .overall-surv.Study-desing-wrap .page-content .headline-var__eyebrow{
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.efficacy.bc-mi .overall-surv.Study-desing-wrap .page-content ul.list:nth-child(3){
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.efficacy.bc-mi .overall-surv.Study-desing-wrap .section-heading p{
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.efficacy.bc-mi .overall-surv.Study-desing-wrap .section-heading p span{
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.efficacy.bc-mi .overall-surv.Study-desing-wrap .page-content h2.headline-var{
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.efficacy.bc-mi .overall-surv.Study-desing-wrap .page-content .headline-var__eyebrow{
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.efficacy.bc-mi .overall-surv.Study-desing-wrap .page-content ul.list:nth-child(3){
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.efficacy.bc-mi .overall-surv.Study-desing-wrap .page-content p.list-title {
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.efficacy.bc-mi .overall-surv.Study-desing-wrap .page-content ul.list{
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}

.efficacy.bc-mi .overall-surv.Study-desing-wrap .page-content .red-box-wrap {
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.efficacy.bc-mi .overall-surv.Study-desing-wrap .page-content .red-box-wrap p {
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.efficacy.bc-mi .Study-desing-wrap .page-content .content-cta {
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.efficacy.bc-mi .Study-desing-wrap .page-content .content-cta:hover {
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.efficacy.bc-mi .Study-desing-wrap .page-content .content-cta:hover a {
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}
.efficacy.bc-mi .bottom-divider.eff-switch-nav.white-bg-desk .page-content {
    background: #fff;
    max-width: 743px;
    margin: 0 auto;
}

.efficacy.bc-mi .break-mobile-only {
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}
.efficacy-footnote {
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}

.efficacy-reference {
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}
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.overall-surv.Study-desing-wrap .table-block table tr:nth-child(1) th:nth-child(2) {
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}
.overall-surv.Study-desing-wrap .table-block table tr:nth-child(1) th:nth-child(1) {
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}

.overall-surv.Study-desing-wrap .table-block table tr.td-sub.renfun td:first-child {
    padding:2px 7px;
}



.overall-surv.Study-desing-wrap .table-block.new-table table tr td:nth-child(2){
    color:#B62428;
    line-height: 17px;
}
.overall-surv.Study-desing-wrap .table-block table tr:nth-child(1) th:nth-child(3) {
     font-size:14px;
     line-height:15px;
    }
.table-block.sf-ar-1.new-table.tbl-baseline-char tr:nth-child(2){
	width:200px;
}
.overall-surv.Study-desing-wrap>td, th{
    color:#4E5055;
    font-size:12px;
    line-height:13px;
    font-family: 'Karbon';
    font-weight:500;
}
.overall-surv.Study-desing-wrap>th:first-child {
    width: 48%;
}
.overall-surv.Study-desing-wrap>td:first-child {
    padding-left: 30px;
    text-indent: -10px;
}
.overall-surv.Study-desing-wrap>table tr:last-child td {
    padding-left: 0px;
    text-indent: 0;
}

.nccn-category {
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    background: #D9E3F3;
    padding: 15px 24px 15px 25px;
    display: flex;
    align-items: center;
    margin: 0 0 12px 0;
}

.category-lhs p{
    color: #003865;
    text-align: center;
    font-family: 'Ubuntu';
    margin: 0;
}

.category-lhs p:first-child {
    font-size: 40.756px;
    font-style: normal;
    font-weight: 700;
    line-height: 41px;
}

.category-lhs p:nth-child(2) {
    font-size: 16.885px;
    font-style: normal;
    font-weight: 700;
    line-height: 21.855px;
}

.category-lhs p:nth-child(3) {    
    font-size: 18.631px;
    font-style: normal;
    font-weight: 700;
    line-height: 21.855px;
}

.category-rhs {
    border-left: 4px solid #003865;
    padding: 0 0 0 12px;
        margin: 0 0 0 12px;
}

.category-rhs h4 {
    color: #003865;
    font-size: 24px;
    font-style: normal;
    font-weight: 700;
    line-height: 25px;
    font-family: 'Ubuntu';
    margin: 0;
    padding: 0 0 4px 0;
}

.category-rhs p {
    color: #003865;
    font-size: 14px;
    font-style: normal;
    font-weight: 400;
    line-height: 16px; /* 114.286% */
    font-family: 'Ubuntu';
    margin: 0;
}

.nccn-footnotes {
    padding: 0 0 0 8px;
}

.nccn-footnotes p {
    color: #555;
    font-size: 10px;
    font-family: 'Ubuntu';
    font-style: normal;
    font-weight: 300;
    line-height: 12px;
    margin: 0 0 2px 0;
}

.nccn-footnotes p:first-child{
    text-indent: -3px;
}


/*******99464 updates*******/

.efficacy.bc-mi .efs-and-os .page-content h2.headline-var{
	padding: 28px 0 33px;
	font-weight: 700;
}
.efficacy.bc-mi .content-box.pfs-chart{
	padding: 35px 10px 22px 7px;
}
.efficacy.bc-mi .content-box.pfs-chart > img{
	margin: 0;
	width: 747px;
}
.efficacy.bc-mi .page-content .pfs-chart+ ul.list,.efficacy.bc-mi .page-content .os-chart+ ul.list{
	margin-bottom: 0;
    padding-left: 27px;
}
.efficacy.bc-mi .content-box.os-chart{
	padding: 28px 4px 35px 15px;
}
.efficacy.bc-mi .content-box.os-chart > img{
	margin: 0;
}
.efficacy.bc-mi .efs-and-os .page-content .headline-var__eyebrow{
	    padding-top: 40px;
    padding-bottom: 0;
    margin-bottom: 0;
}
.efficacy.bc-mi .efs-and-os .page-content .headline-var--sub{
	margin-top: 10px;
	margin-bottom: 40px;
}
.efficacy.bc-mi .efs-and-os .page-content h3.headline-var--sub.headline2{
    margin-top: 30px;
}
.efficacy.bc-mi .efs-and-os .footnote.footnote--content-page.pb0{
	margin-left: 0;
}
.efficacy.bc-mi .efs-and-os .footnote.footnote--content-page p{
	margin-bottom: 4px;
}



/*******99464 updates*******/



/* Mobile */

@media screen and (max-width: 991.5px) {

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        margin: 20px 0 0;
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	padding: 16px 12px 15px 12px;
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        padding: 0 0 0 12px;
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    .overall-surv.Study-desing-wrap .table-block.new-table table tr td:nth-child(2){
        width: 185px;
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        display:block;
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        font-size: 26px;
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        padding-left: 15px;
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        padding: 9.5px 15px;
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        margin: 25px 0 25px;
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    .efficacy.bc-mi .content-box--two-col__wrapper {
        flex-direction: column;
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    .content-box-image--wrapper-no-scroll img {
        width: 100%;
        max-width: 100%;
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      .efficacy.bc-mi .content-image {
        margin: 25px auto 40px;
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     .efficacy.bc-mi  .content-image img {
        max-width: 100%;
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     .efficacy.bc-mi  .content-box.content-box--callout {
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    .efficacy.bc-mi .page-content  .content-cta {
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        height: 51px;
        padding: 5px 30px;
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        margin-bottom: 0;
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        padding: 34px 22px 2px 17px;
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    .efficacy.bc-mi .overall-surv.surgical-data .page-content .completing-table p.box-title{
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    /* Hide scrollbar for IE, Edge and Firefox */
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      -ms-overflow-style: none;  /* IE and Edge */
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        overflow: hidden;
        width: 100%;
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        padding: 15px 10px 20px 10px;
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    .efficacy.bc-mi .content-box-image--wrapper img {
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        font-size: 10px;
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        margin: 0px 0 0 -21px;
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        padding-left: 22px;
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        padding-top: 38px;
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        text-align: center;
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    .efficacy.bc-mi .content-box. {
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    	height: 92px;
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        top: 275px;
        left: 26vw;
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    .efficacy-reference {
        letter-spacing: 0.01px;
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    td:first-child, th:first-child {
        position: sticky;
        left: 0;
        background: #ffffff;
        z-index: 1;
        line-height: normal;
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    th:first-child>img {
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    th:last-child img  {
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    .table-block {
            overflow: scroll;
            position: relative;
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     .overall-surv.surgical-data table{
        width: 500px !important;
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     .overall-surv.surgical-data td:first-child, .overall-surv.surgical-data th:first-child{
        width: 140px;
        max-width: 140px;
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    .overall-surv.surgical-data td, .overall-surv.surgical-data th{
        width: 150px;
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    .paitent-decision-block {
        width: 103px;
        right: -95px;
        top: 59px;
        z-index: 0;
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    .efficacy.bc-mi .overall-surv.surgical-data .page-content .paitent-decision-block p{
        font-size: 10px;
    }
    .paitent-decision-block::before, .paitent-decision-block::after{
        top: 10px;
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    .backGroundWhite{
		padding:0 15px
    }


    .table-block.sf-ar-1.new-table.tbl-baseline-char table {
        width: 780px;
        position: relative;
    }
    .table-block.sf-ar-1.new-table.tbl-baseline-char th:first-child, .table-block.sf-ar-1.new-table.tbl-baseline-char td:first-child {
        /*width: 200px;*/
    	width:170px;
    	z-index: 1;
    }
    .paitent-treated-block{
		right: -160px;
        top: 373px;
    }
    .paitent-treated-block.pt2 {
        top: 641px;
    }
    .paitent-treated-block.pt3 {
        top: 556px;
    }


	.exploratory-analysis .table-block.mobile-only #EFSGraph2{
        margin-left: -2px;
    margin-bottom: -15px;
    }

	.nccn-category {
        padding: 20px 6px 5px 10px;
		flex-wrap: wrap;
    }

    .category-rhs h4 {
        font-size: 16px;
        line-height: 18px;
    }

    .category-lhs p:nth-child(2) {
        font-size: 17.528px;
        line-height: 20px;
    }

    .category-lhs p:nth-child(3) {
        font-size: 19px;
        line-height: 20px;
    }

	.nccn-category p.mobile-only.nccn-category-p {
        width: 100%;
        color: #003865;
        font-size: 14px;
        font-style: normal;
        font-weight: 400;
        line-height: 16px;
    	font-family: 'Ubuntu';
		margin: 13px 0;
    	padding: 0 5px 0 0;
    }

    .nccn-category .category-rhs {
    	flex: 1;
        /*padding: 0 0 0 7px;
        margin: 0 0 0 7px;*/
    }

	.nccn-footnotes {
        padding: 0 0 0 3px;
		margin: 0 0 50px 0;
    }

	.overall-surv.surgical-data tr:nth-child(2), 
    .overall-surv.surgical-data tr:nth-child(3),
    .overall-surv.surgical-data tr:nth-child(4){
        border:none;
    }
    .overall-surv.surgical-data tr:nth-child(2) td:first-child:before {
        position: absolute;
        content: 'Patients who did not undergo surgery–no. (%)';
        border-top: 1px solid #c6c6c8;
        height: 100%;
        width: 100%;
        top: -1px;
        z-index:10;
        background: #FFF;
        left: 0;
        padding: 4px 10px;
    }
    
    
    .overall-surv.surgical-data tr:nth-child(3) td:first-child:before {
        position: absolute;
        content: 'Patient decision';
        border-top: 1px solid #c6c6c8;
        height: 100%;
        width: 100%;
        top: -1px;
        z-index:10;
        background: #FFF;
        left: 0;
        padding: 4px 10px;
    }
    
    .overall-surv.surgical-data tr:nth-child(4) td:first-child:before {
        position: absolute;
        content: 'Unfit for surgery';
        border-top: 1px solid #c6c6c8;
        height: 100%;
        width: 100%;
        top: -1px;
        z-index:10;
        background: #FFF;
        left: 0;
        padding: 4px 10px;
    }


	.tbl-baseline-char table tr:nth-child(9) td:first-child:before {
        position: absolute;
        content: '';
        border-top: 1px solid #c6c6c8;
        height: 5px;
        width: 100%;
        top: -1px;
        z-index:10;
        left: 0;
        padding: 0;
        background: #FFF;
    }
    
    .tbl-baseline-char table tr:nth-child(10) td:first-child:before {
        position: absolute;
        content: '';
        border-top: 1px solid #c6c6c8;
        height: 5px;
        width: 100%;
        bottom: -4px;
        z-index:10;
        left: 0;
        padding: 0;
        background: #FFF;
    }
    
    
    .tbl-baseline-char table tr:nth-child(11) td:first-child:before {
        position: absolute;
        content: '';
        border-top: 1px solid #c6c6c8;
        height: 5px;
        width: 100%;
        bottom: -4px;
        z-index:10;
        left: 0;
        padding: 0;
        background: #FFF;
    }

	/*******99464 updates*******/

	.content-box.pfs-chart img:nth-child(1){
		    margin-top: 13px;
    		width: 100%;
    }
	.content-box.os-chart img:nth-child(1){
		    margin-top: 20px;
    		        width: 100%;
    }
    .content-box.pfs-chart img:nth-child(2),.content-box.os-chart img:nth-child(2){
		/*display: flex;
        justify-self: center; */
        margin-top: 26px;
    	margin-left: calc(50% - 105px);
    	max-width: 210px;
    }        
     .efficacy.bc-mi .content-box-image--wrapper img#pcrGraph1{
		width: 132px;
		height: 479px;
		margin: 0px 0 0 0;
		max-width: 132px;
	}
	.efficacy.bc-mi .efs-and-os .content-box-image--wrapper{
		margin: 30px 0 0 0;
	}
	.efficacy.bc-mi .content-box-image--wrapper img#pcrGraph2{
		height: 478px;
		margin: 1px 0 0 0;
	}                  
	.efficacy.bc-mi .efs-and-os .page-content>h2.headline-var:first-child{
		padding: 33px 0 45px;
	}
	.efficacy.bc-mi .efs-and-os .page-content .headline-var__eyebrow{
		padding-top: 15px;
	}
	.efficacy.bc-mi .efs-and-os .page-content>h3.headline-var--sub{
		padding-right: 20px;
	}
	.efficacy.bc-mi .content-box.pcr-table .hscroll-thumb span{
		width: 120px!important;
    	right: 176px !important;
	}
	.efficacy.bc-mi .efs-and-os .footnote.footnote--content-page.pb0{
		width: 101.5%;
     }
	.efficacy.bc-mi .efs-and-os .content-box-image--wrapper img.mobile-only1.hand-icon{
		top: 40%;
		left: 29vw;
	}
	/*.efficacy.bc-mi .content-box.pcr-table .hscroll-bar{
		width: 299px;
        margin: 20px auto 10px;
	}*/
	#efs-section{
		scroll-margin-top: 113px;
	}




		/*******99464 updates*******/


}


@media screen and (min-width: 992px) {
    .bc-mi main#maincontent {
        padding-top: 142px;
    }

    /*******99464 updates*******/

	.efficacy.bc-mi .content-box.pfs-chart .box-title,.efficacy.bc-mi .content-box.os-chart .box-title{
		    top: -12px;
   	}
    .efficacy.bc-mi .content-box.pcr-table{
		padding-top: 35px;
	}                        
    .efficacy.bc-mi .content-box.pcr-table .box-title{
		max-width: 503px;
        line-height: 16px;
        top: -12px;
    }
	.efficacy.bc-mi .page-content .pfs-chart+ ul.list>li:last-child{
		padding-right: 43px;
	}

	.efficacy.bc-mi .page-content {
        max-width: 773px;
    }

	/*******99464 updates*******/

}



	.tbl-baseline-char {
        padding: 0 0 37px 0;
    }

@media screen and (min-width: 320px) and (max-width: 365px) {
    .efficacy.bc-mi .content-box .box-title {
        width: 93%;
    }
}

@media screen and (min-width: 749px) and (max-width: 991px) {

	.efficacy.bc-mi .content-box-image--wrapper img.mobile-only1.hand-icon, 
	.hscroll-bar.mobile-only, .hr-scroll-txt.mobile-only, .table-block.mobile-only.content-box-image--wrapper,
	.efficacy.bc-mi .content-box.pfs-chart>.mobile-only,
	.efficacy.bc-mi .content-box.os-chart>.mobile-only, 
    .efficacy.bc-mi .content-box .content-box-image--wrapper-no-scroll{
		display: none;
    }

	.efficacy.bc-mi .content-box > img{
		display: block !important;
		max-width: 100%;
	}
	.overall-surv.surgical-data table {
		width: 100% !important;
    	max-width: 724px !important;
	}
	.efficacy.bc-mi .content-box-image--wrapper {
    	width: 100%;
		overflow-x: visible;
        -webkit-overflow-scrolling: initial;
	}
	.paitent-decision-block {
        width: 134px;
        right: 150px;
        top: 76px;
    }
	.efficacy.bc-mi .overall-surv.surgical-data .page-content .paitent-decision-block p {
        font-size: 13px;
    }
	.paitent-decision-block::before, .paitent-decision-block::after {
        top: 15px;
    }

	.overall-surv.surgical-data td:first-child, .overall-surv.surgical-data th:first-child {
        max-width: 210px;
		width: auto;
    }

	.overall-surv.surgical-data td, .overall-surv.surgical-data th {
        max-width: 223px;
    }

	.table-block.sf-ar-1.new-table.tbl-baseline-char table {
        width: 100%;
    }

	.table-block.sf-ar-1.new-table.tbl-baseline-char th:first-child, .table-block.sf-ar-1.new-table.tbl-baseline-char td:first-child {
        width: 230px;
    }
	.table-block.sf-ar-1.new-table.tbl-baseline-char th:nth-child(2), .table-block.sf-ar-1.new-table.tbl-baseline-char td:nth-child(2) {
        width: 270px;
    }

    .efficacy.bc-mi .content-box-image--wrapper.table-block {
        overflow: visible;
        position: revert;
    }
    
    .paitent-treated-block {
        right: 125px;
        top: 400px;
    }
	.paitent-treated-block.pt2 {
        top: 667px;
        padding: 6.5px 5px;
    }
    .paitent-treated-block.pt3 {
        top: 591px;
        padding: 6.5px 5px;
    }
	.table-block.sf-ar-1.new-table.tbl-baseline-char th, .table-block.sf-ar-1.new-table.tbl-baseline-char td{
		line-height: inherit;
	}
}