@import url('https://fonts.googleapis.com/css2?family=Ubuntu:ital,wght@0,400;0,700;1,400;1,700&display=swap');

@font-face {
    font-family: 'Karbon';
    src: url('/etc/designs/code/website-services/us/imfinzi-com/fonts/Karbon-Regular.woff') format('woff');
    font-weight: normal;
    font-style: normal;
    font-display: swap;
}
@font-face {
    font-family: 'Karbon-Bold';
    src: url('/etc/designs/code/website-services/us/imfinzi-com/fonts/Karbon-Bold.woff') format('woff');
    font-weight: bold;
    font-style: normal;
    font-display: swap;
}
@font-face {
    font-family: 'Karbon-Medium';
    src: url('/etc/designs/code/website-services/us/imfinzi-com/fonts/Karbon-Medium.woff') format('woff');
    font-weight: 500;
    font-style: normal;
    font-display: swap;
}


/*body.safety.bc-muscle-invasive.bc-mi {
    background-image: none;
    background-color: #fff;
}
.header-iparsys.iparsys.parsys{
	display:none;
}
.sticky-isi-wrapper {
    display: none !important;
}.header-iparsys.iparsys.parsys {
    display: none;
}*/
.footnote.footnote2 p{
	gap:0;
}
.safety.bc-mi main#maincontent {
    background: linear-gradient(180deg, rgba(228, 237, 252, 0.00) 0%, #E4EDFC 100%);
}

.desktop-only, .desktop-only1{
    display: block;
}
.mobile-only, .mobile-only1{
    display: none;
}

.page-content-head {
    background: #fff;
    max-width: 888px;
    margin: 0 auto;
}
.safety.bc-mi .page-content {
    background: #fff;
    max-width: 773px;
    margin: 0 auto;
}

.safety.bc-mi .page-content.page-head-wrap {
    margin: 0 auto !important;
    max-width: 888px;
}

.safety.bc-mi .page-heading h1 {
    font-family: 'Ubuntu', sans-serif;
    font-size: 58.6px;
    font-style: normal;
    font-weight: 700;
    line-height: normal;
    text-transform: uppercase;
    color: #003865;
    padding: 20px 0 0 55px;
    margin: 0 !important;
}
.safety.bc-mi .page-heading p.grey-head {
    font-size: 18px;
    line-height: 28px;
    font-weight: 700;
	color: #555555;
    margin: 10px 55px 30px;
    font-family: 'Ubuntu';
}
.safety.bc-mi .page-heading p.grey-head a {
    color: #003865;
    text-decoration: underline;
}
.section-heading {
    border-top: 1px solid #003865;
}
.section-heading p {
    padding-top: 10px;
    padding-left: 55px;
    margin: 0;
    padding-bottom: 10px;
}
.section-heading span {
    color: #ffffff;
    background: #07729B;
    font-size: 18px;
    line-height: normal;
    font-weight: 700;
    padding: 11px 25px;
    border-bottom-left-radius: 16px;
    border-bottom-right-radius: 16px;
    font-family: 'Ubuntu', sans-serif;
}
.page-content h2 {
    font-family: 'Ubuntu', sans-serif;
    font-size: 24px;
    font-style: normal;
    font-weight: 700;
    line-height: normal;
    margin: 33px 0;
    color: #003865;
}
.content-box {
    border: 1px solid #03315D;
    border-left: 10px solid #03315D;
    border-bottom-right-radius: 32px;
    padding: 15px;
    position: relative;
}
.content-box .box-title {
    font-family: 'Ubuntu', sans-serif;
    font-size: 14px;
    font-style: normal;
    font-weight: 700;
    line-height: 22px;
    text-transform: uppercase;
    color: #003865;
    margin: 0;
    position: absolute;
    top: -14px;
    left: 0px;
    background: #fff;
    padding: 0 10px 0 15px;
}
.content-box .box-title::before {
    content: '';
    background: #03315d;
    position: absolute;
    left: -10px;
    top: 6px;
    width: 10px;
    height: 12px;
}
.efficacy-la .content-box .box-title {
    font-size: 16px;
}
.footnote {
    margin: 25px 0 3px;
}
.footnote p {
    font-family: 'Ubuntu', sans-serif;
    font-size: 12px;
    font-style: normal;
    font-weight: 400;
    line-height: 16px;
    margin: 0;
    color: #555;
}
.footnote p:last-child {
    text-indent: -0.3px;
}
.footnote p:last-child sup {
    font-size: 50%;
}
.safety.bc-mi ul.list {
    padding: 0 0 0 24px;
    margin: 34px 0;
}
.footnote p:last-child sup+sup {
    font-size: 9px;
    top: -4px;
}
.safety.bc-mi .list.mar28 {
    margin-top: 17px !important;
}

.safety.bc-mi .list.list1.mar43 {
    margin-top: 14px !important;
}

.safety.bc-mi .list1.list li {
    font-weight: 400;
}
.safety.bc-mi .efficacy-dr .list.list1.mar43{
	margin-bottom: 0;
}
.safety .efficacy-dr .footnote{
	padding-bottom: 30px;
}

.safety.bc-mi .list li {
    font-family: 'Ubuntu', sans-serif;
    font-size: 16px;
    font-style: normal;
    font-weight: 700;
    line-height: normal;
    color: #555;
    list-style-type: none;
    text-indent: -8px;
    margin-left: 2px;
    letter-spacing: -0.1px;
}

.safety.bc-mi .list.mar28 li{
	font-weight:400;
 }

.safety.bc-mi .list li:before{
	color: #7098D2;	
    /*left: -15px;
    font-size: 25px;
   	visibility: hidden;
    line-height: normal;*/
}
.safety.bc-mi .list li ul {
    padding: 4px 23px 0 25px;
}
.safety.bc-mi .list.mb-0 ul {
    padding: 4px 30px 0 24px !important;
}

.safety.bc-mi .list.list-mt ul {
    padding: 4px 30px 0 24px !important;
}
.safety.bc-mi .list li ul li {
    font-weight: 400;
    padding-bottom: 3px;
}
.safety.bc-mi .list li ul li:before {
    color: #555555;
    left: -10px;
    line-height: normal;
    visibility: visible;
}
.safety.bc-mi ul.list:last-child {
    padding-bottom: 76px;
    margin-bottom: 0;
}

.safety.bc-mi .list.list1.mar30 {
    margin-top: 19px !important;
}

.efficacy-dr .page-content h2 {
    margin: 40px 0;
}

.dr-content {
    display: flex;
    align-items: center;
    justify-content: normal;
    padding: 20px;
}
.dr-content h3 {
    font-family: 'Ubuntu', sans-serif;
    font-size: 42px;
    font-style: normal;
    font-weight: 700;
    line-height: 22px;
    color: #003865;
    margin: 0;
}
.dr-content h3 sup {
    font-size: 60%;
}
.dr-content p {
    font-family: Ubuntu;
    font-size: 16px;
    font-style: normal;
    font-weight: 700;
    line-height: normal;
    margin: 0 0 0 15px;
}
ul.list.list1 li {
    font-weight: 400;
}
.color-red {
    color: #AC182E !important;
}
.head-h4 {
    font-family: 'Ubuntu', sans-serif;
    font-size: 20px;
    font-style: normal;
    font-weight: 500;
    line-height: normal;
    color: #003865;
    margin: 20px 0 0;
}
.head-h4 sup {
    font-weight: 400;
}
ul.list.list1 {
    margin: 15px 0;
}
.page-content.page-content-la {
    margin-top: 60px !important;
}
.safety .efficacy-dr ul.list:last-child {
    padding-bottom: 35px;
}
.page-content.page-content-la .footnote p {
    display: block;
    text-indent: -3px;
}
.page-content.page-content-la .footnote p:first-child {
    text-indent: -8px;
    margin-left: 4px;
}
.page-content.page-content-la ul.list.list1 {
    margin-top: 20px;
}
.footnote.footnote1 p sup {
    font-size: 75%;
}
.footnote.footnote1 {
    margin-left: 13px;
    margin-bottom: 0px;
}
.footnote.footnote1 p {
    margin-bottom: 0;
    padding-right: 10px;
    padding-bottom: 3px;
}
.footnote.footnote1 p:first-child {
    text-indent: -5px !important;
}

.switch-section a {
    font-family: 'Ubuntu', sans-serif;
    font-size: 16px;
    font-style: normal;
    font-weight: 700;
    line-height: normal;
    color: #003865;
}

/*.switch-section a:hover {
    text-decoration: none;
}*/
.switch-section a:first-child {
    background-image: url(/content/dam/website-services/us/434-imfinzi-com/hcp-bc-mi/Global/nav-back.svg);
    background-repeat: no-repeat;
    background-position: left;
    background-size: 20px;
    padding-left: 24px;
    height: 20px;
}
.switch-section a:last-child {
    background-image: url(/content/dam/website-services/us/434-imfinzi-com/hcp-bc-mi/Global/nav-next.svg);
    background-repeat: no-repeat;
    background-position: right;
    background-size: 20px;
    padding-right: 24px;
    height: 20px;
}

.page-switch-block {
    background: #fff;
    max-width: 888px;
    margin: 0 auto;
    margin-bottom: 42px;
}

.page-content-switch {
    max-width: 743px;
    margin: 0 auto;
}

.switch-section {
    display: flex;
    justify-content: space-between;
    /* padding-left: 40px; */
    /* padding-right: 22px; */
    padding: 35px 5px 64px 38px;
}

.efficacy-ar {
    background: #fff;
    max-width: 888px;
    margin: 0 auto;
}
.efficacy-dr {
    background: #fff;
    max-width: 888px;
    margin: 0 auto;
}

.efficacy-la {
    background: #fff;
    max-width: 888px;
    margin: 0 auto;
}

ul.list.mb-0 li ul li:before {
	    content: '-';
}

ul.list.list-mt li ul li:before {
	    content: '-';
}

/*ul.list.mb-0 ul:before {
	content: "•";
    font-size: 20px;
    top: 2px;
    line-height: 20px;
    position: relative;
    left: -10px;
    color: #000;
    top: -24px;
    left: -39.5px;
    color: #7098D2;
    font-size: 25px;
}

ul.list.list-mt ul:before {
	content: "•";
    font-size: 20px;
    top: 2px;
    line-height: 20px;
    position: relative;
    left: -10px;
    color: #000;
    top: -25px;
    left: -39.5px;
    color: #7098D2;
    font-size: 25px;
}*/

.adverse-reactions__table {
    border-collapse: collapse;
    width: 100%;
    font-family: Karbon;
    font-size: 15px;
    font-style: normal;
    font-weight: 400;
    line-height: normal;
  }
  .adverse-reactions__table tr:first-of-type {
    height: 35px;
}
  .adverse-reactions__table th, 
  .adverse-reactions__table td {
    border: 1px solid #ddd;
    padding: 4px;
    text-align: left;
  }
  .adverse-reactions__table th {
    background-color: white;
    font-weight: bold;
    text-align: center;
    font-family: 'Karbon-Bold';
  }

  .adverse-reactions__table .category {
    font-weight: 700;
    color: #4D4D4F;
    background-color: white;
    border-right: none;
  }

  .adverse-reactions__table td:first-child {
    width: 192px;
    white-space: nowrap;
    max-width: 192px;
}

  .adverse-reactions__table .subcategory {

  }
  .adverse-reactions__table th.left {
    padding-top: 40px;
}
  .adverse-reactions__table .red-text {
    color: #C0403A;
    font-weight: 700;
    font-family: 'Karbon-Bold';
  }
  .adverse-reactions__table .centered {
    text-align: center;
  }
  .adverse-reactions__table-wrapper sup {
	font-family: Arial;
	font-size: 65%;
}
td.category {
    font-family: 'Karbon-Bold';
}
  .adverse-reactions__table .subheader-cell {
    border-top: none;
  }
  .adverse-reactions__table .light-background {
    background-color: #EDF0F8;
    width: 18.9%;
    
  }
  .adverse-reactions__table .left {
    text-align: left;
  }
  .adverse-reactions__table td:first-child,
.adverse-reactions__table th:first-child {
    border-left: none;
}

.adverse-reactions__table td:last-child,
.adverse-reactions__table th:last-child {
    border-right: none;
}

.adverse-reactions__table th.subheader-cell:last-child {
        font-family: Karbon;
        font-weight: 400;
}

.adverse-reactions__table.laboratory-abnormalities__table td:first-child {
    white-space: normal;
    width: 206px;
    max-width: 206px;
}

.adverse-reactions__table.laboratory-abnormalities__table .light-background {
    width: 18%;
}


@media screen and (max-width: 991px) {
    .desktop-only{
        display: none;
    }
    .mobile-only{
        display: block;
    }
    .page-content {
        padding: 0 15px;
    }
    .safety.bc-mi main#maincontent {
        background: #fff;
    }
    .page-heading h1 {
        font-size: 26px;
        margin: 0 0 15px;
    }
    .section-heading p{
        padding-top: 8px;
        padding-left: 15px;
    }
    .section-heading span{
        padding: 9.5px 15px;
    }
    .page-content h2 {
        margin: 37px 0 45px;
    }
    .footnote {
        margin: 35px 0 13px;
    }
    .footnote p {
        font-size: 10px;
        align-items: baseline;
        padding-right: 16px;
    }
	.footnote.footnote2 p {
        text-indent: -4px;
    }
    .footnote p:last-child sup {
        font-size: 64%;
    }
    .safety.bc-mi ul.list {
        margin: 46px 0;
    }
    .mb-0 {
        margin-bottom: 0 !important;
    }
    .list-mt {
        margin-top: 31px !important;
    }
    .safety.bc-mi ul.list:last-child {
        margin-bottom: 46px;
    }
    .efficacy-dr .page-content h2 {
        margin: 25px 0 30px;
    }
    .efficacy-ar .content-box .box-title {
        padding: 0 0px 0 10px;
        line-height: 16px;
        width: 90%;
    }
    .efficacy-dr .content-box .box-title {
        padding: 0 0px 0 10px;
        width: 95%;
        letter-spacing: -0.45px;
    }
    .efficacy-dr .content-box p.box-title.box-title-dis {
        padding: 0 20px 0 10px;
    }
    .dr-content {
        justify-content: center;
        padding: 20px 0px 14px 0px;
        padding: 32px 0px 14px 0px;
        flex-wrap: wrap;
        gap: 35px;
    }
    .dr-content h3 {
        font-size: 80px;
    }
    .dr-content p {
        margin: 0;
    }
    .dr-content h3 sup {
        font-size: 54%;
    }
    .safety .list li {
        font-weight: 400;
    }
    .mar28 {
        margin: 28px 0 40px !important;
    }
    ul.list.mar28 li {
        letter-spacing: -0.2px;
    }
    .mar43 {
        margin: 43px 0 !important;
    }
    .mar30 {
        margin: 30px 0 60px !important;
    }
    .page-content.page-content-la {
        margin-top: 90px;
    }
    .page-content.page-content-la .content-box .box-title {
        line-height: normal;
        max-width: 300px;
    }
    .efficacy-la .footnote {
        margin-bottom: 0;
    }
    .page-content.page-content-la .footnote p {
        padding-right: 0;
    }    
    .efficacy-la .footnote.footnote1 {
        margin-left: 0;
    }
    .switch-section {
        padding-left: 22px;
        padding-right: 22px;
    }
    
    .page-content-switch {
        max-width: 883px;
        margin: 0 auto;
        padding: 55px 15px 60px 15px;
        background: #FFF;
    }
    
    .footnote.footnote1 p {
        padding-bottom: 3px;
        margin-bottom: 0;
    }

    /*.footnote p:last-child {
        text-indent: -3px;
        padding-left: 3px;
    }*/
	.safety.bc-mi .page-heading h1{
        font-size: 26px;
        padding: 12px 0 6px 0;
	}
	.safety.bc-mi .page-heading p.grey-head {
    	font-size: 16px;
        line-height: 20px;
        margin: 0 0 15px;
        letter-spacing: -0.52px;
    }

   /* .content-box-image--wrapper.content-box-image--wrapper1 img.mobile-only{
        width: 190%;
    }*/

	td:first-child, th:first-child {
        position: sticky;
        left: 0;
        background: #ffffff;
        z-index: 1;
    }

    img#LabAbnormalityGraph1{
    	height: 490px;
        margin: 10px auto 20px;
    }
    img#LabAbnormalityGraph2{
        height: 490px;
        margin: 10px auto 20px;
    }
    .content-box-image--wrapper-Lab-Abnormality .content-box-image--wrapper .table-new-safety{
            margin-top: 32px;
    }

    .adverse-reactions__table-wrapper {
        overflow-x: auto;
        position: relative;
        max-width: 100%;
    }
    
    .adverse-reactions__table {
        width: max-content; 
        min-width: 100%;
        border-collapse: separate;
        border-spacing: 0;
    }
    
    .adverse-reactions__table th,
    .adverse-reactions__table td {
        white-space: nowrap; 
    }
    
    .adverse-reactions__table th[rowspan="2"], .adverse-reactions__table td:first-child {
    /* position: sticky; */
    left: 0;
    z-index: 3;
    background: white;
    min-width: 200px;
    max-width: 200px;
	}
    
    .adverse-reactions__table th[rowspan="2"] {
        z-index: 4;
        text-align: left;
    }
    .adverse-reactions__table th[rowspan="2"], .adverse-reactions__table td:first-child {
        box-shadow: 2px 0 5px rgba(0, 0, 0, 0.1); 
    }
   .adverse-reactions__table td.category {
    position: sticky;
    left: 0;
    z-index: 2;
    background: white;
    font-weight: bold;
    white-space: break-spaces;
	}

	.page-content-la .adverse-reactions__table-wrapper.content-box-image--wrapper {
        margin-top: 49px;
    }
	.footnote p:last-child sup+sup {
		font-size:75%;
     }

	/* Hide scrollbar for Chrome, Safari and Opera */
    .hscroll-bar::-webkit-scrollbar {
      display: none;
    }
    
    /* Hide scrollbar for IE, Edge and Firefox */
    .hscroll-bar {
      -ms-overflow-style: none;  /* IE and Edge */
      scrollbar-width: none;  /* Firefox */
    }

	.hscroll-bar {
        margin-top: 20px;
        overflow: auto;
        white-space: nowrap;
        transform: rotate(180deg);
        margin-bottom: 10px;
        border: 1px solid #808184;
    }
    
    .hscroll-thumb {
        background: #ffffff;
        height: 9px;
        position: relative;
    }
    
    .hscroll-thumb span {
        position: absolute;
        height: 9px;
        background: #808184;
    }


}
@media screen and (max-width: 767px) {
    .desktop-only1{
        display: none;
    }
    .mobile-only1{
        display: block;
    }
    .content-box-image--wrapper {
        width: 100%;
        overflow-x: auto;
        -webkit-overflow-scrolling: touch;
    }
	.adverse-reactions__table-wrapper.content-box-image--wrapper {
        margin-top: 15px;
    }
    .content-box-image--wrapper img {
        margin: 40px auto 30px;
    }
    .scroll-indicator {
        display: flex;
        align-items: center;
        gap: 9px;
        justify-content: center;
        margin-top: 10px;
        font-size: 14px;
        color: #666;
        flex-direction: column-reverse;
    }
    .efficacy-ar .scroll-indicator.mobile-only {
        margin-top: 30px;
    }
    span.scroll-label, .hr-scroll-txt p {
        color: #808184;
        font-family: Ubuntu;
        font-size: 14px;
        font-style: normal;
        font-weight: 700;
        line-height: normal;
        text-transform: uppercase;
        text-align: center;
        margin: 0;
    }
    .scroll-bar {
        position: relative;
        height: 11px;
        border: 1px solid #808184;
        overflow: hidden;
        /*width: 316px;*/
    	width:100%;
        margin: 0 auto;
    }
    .scroll-bar-progress {
        position: absolute;
        height: 100%;
        background-color: #808184;
        width: 120px;
    }
    ::-webkit-scrollbar {
        display: none; 
    }
    img.mobile-only1.hand-icon {
        margin: 0;
        position: absolute;
        top: 41%;
        left: 36%;
		width: 91px;
    }
	.adverse-reactions__table-wrapper img.mobile-only1.hand-icon {
        top: 54%;
        left: 32%;
        z-index: 3;
    }
    .safety.bc-mi .list.mb-0 li {
        letter-spacing: -0.4px !important;
    }
    
    .safety.bc-mi .list.mb-0 ul {
        padding: 4px 0px 0 24px !important;
    }
    
    .safety.bc-mi .list.list-mt ul {
        padding: 4px 0px 0 24px !important;
    }
    ul.list.list-mt ul:before,  ul.list.mb-0 ul:before{
		top: -42px;
	}

    .safety.bc-mi .list.mar28 {
        margin-top: 28px !important;
    }
    
    .safety.bc-mi .list.list1.mar43 {
        margin-top: 43px !important;
        padding-bottom: 10px;
    }

    .safety.bc-mi .list.list1.mar30 {
        margin-top: 32px !important;
    }
    
    .efficacy-ar .content-box .box-title::before {
        top: 3px;
    }
    
    .efficacy-dr .content-box .box-title::before {
        top: 7px;
    }
    
    .efficacy-la .box-title {
        padding-top: 4px;
    }
    
    .efficacy-la .content-box .box-title::before {
        top: 9px !important;
    }
    
    .efficacy-ar .list.list-mt {
        margin-top: 31px !important;
         margin-bottom: 0 !important;
    }
    
    .safety.bc-mi ul.list:last-child{
        padding-bottom: 49px;
    }
    
    .safety.bc-mi .efficacy-dr .list.list1.margin-0 {
        margin: 0;
        padding-top: 32px;
        padding-bottom: 59px;
    }
    
    .footnote.footnote1 p:first-child {
        text-indent: -4px !important;
        margin-left: 0 !important;
    }
    
    .page-switch-block {
        margin-bottom: 0;
    }


}

.efficacy-la .content-box .box-title::before {
    content: '';
    background: #03315d;
    position: absolute;
    left: -10px;
    top: 6px;
    width: 10px;
    height: 12px;
}

@media screen and (min-width: 992px) {
    .bc-mi main#maincontent {
        padding-top: 142px;
    }
}