@font-face {
    font-family: 'SolexOT-Bold';
    font-weight: normal;
    font-style: normal;
    font-display: swap;
    src: url('/etc/designs/code/website-services/us/imfinzi-com/fonts/SolexOT-Bold.eot');
    src: url('/etc/designs/code/website-services/us/imfinzi-com/fonts/SolexOT-Bold.eot?iefix') format('embedded-opentype'), url('/etc/designs/code/website-services/us/imfinzi-com/fonts/SolexOT-Bold.ttf') format('truetype');
}

@font-face {
    font-family: 'HelveticaNeueLTStd-BdCn';
    src: url(/etc/designs/code/website-services/us/imfinzi-com/fonts/HelveticaNeueLTStd-BdCn.eot);
    src: local('?'), url(/etc/designs/code/website-services/us/imfinzi-com/fonts/HelveticaNeueLTStd-BdCn.woff) format('woff'), url(/etc/designs/code/website-services/us/imfinzi-com/fonts/HelveticaNeueLTStd-BdCn.ttf) format('truetype'), url(/etc/designs/code/website-services/us/imfinzi-com/fonts/HelveticaNeueLTStd-BdCn.svg) format('svg');
    font-weight: 400;
    font-style: normal;
    font-display: swap;
}

@font-face {
    font-family: 'HelveticaNeueLTStd-LtCn';
    src: url(/etc/designs/code/website-services/us/imfinzi-com/fonts/HelveticaNeueLTStd-LtCn.eot);
    src: local('?'), url(/etc/designs/code/website-services/us/imfinzi-com/fonts/HelveticaNeueLTStd-LtCn.woff) format('woff'), url(/etc/designs/code/website-services/us/imfinzi-com/fonts/HelveticaNeueLTStd-LtCn.ttf) format('truetype'), url(/etc/designs/code/website-services/us/imfinzi-com/fonts/HelveticaNeueLTStd-LtCn.svg) format('svg');
    font-weight: 400;
    font-style: normal;
    font-display: swap;
}

@font-face {
    font-family: 'HelveticaNeueLTStd-MdCn';
    src: url('/etc/designs/code/website-services/us/imfinzi-com/fonts/HelveticaNeueLTStd-MdCn.otf');
    font-display: swap;
}

@font-face {
    font-family: 'Roboto-Medium';
    src: url('fonts/Roboto-Medium.eot');
    src: local('?'), url('/etc/designs/code/website-services/us/imfinzi-com/fonts/Roboto-Medium.woff') format('woff'), url('/etc/designs/code/website-services/us/imfinzi-com/fonts/Roboto-Medium.ttf') format('truetype'), url('/etc/designs/code/website-services/us/imfinzi-com/fonts/Roboto-Medium.svg') format('svg');
    font-weight: normal;
    font-style: normal;
    font-display: swap;
}

@font-face {
    font-family: "HelveticaNeueLTStd-cn";
    src: url('/fonts/HelveticaNeueLTStd-cn.eot');
    src: local('?'), url('/etc/designs/code/website-services/us/imfinzi-com/fonts/HelveticaNeueLTStd-cn.woff') format('woff'), url('/etc/designs/code/website-services/us/imfinzi-com/fonts/HelveticaNeueLTStd-cn.ttf') format('truetype'), url('/etc/designs/code/website-services/us/imfinzi-com/fonts/HelveticaNeueLTStd-cn.otf') format('opentype');
    font-weight: normal;
    font-style: normal;
    font-display: swap;
}

.modal-backdrop.fade.in {
    display: none !important;
}

.btc-data-popup.btc-data-popup.modal-open {
    overflow: initial !important;
    padding-right: 0 !important;
}
body.additional-analyses.btc-hcp.btc-popup-1.modal-open.mobile, body.dosing.btc-hcp {
    padding-right: 0 !important;
}
body.about-btcs.btc-hcp.desktop.btc-popup-1.modal-open {
    padding-right: 0 !important;
}
body.safety.btc-hcp.desktop.btc-popup-1.modal-open {
    padding-right: 0 !important;
}

sup.customSup {
    top: -0.4em;
}

.pink-color {
    color: #F615FFDE;
}

ul.hypen-list {
    padding-left: 20px !important;
}

.about-btcs ul.hypen-list {
    padding-left: 47px !important;
}

.hypen-list li:before {
    content: '–' !important;
    left: -20px !important;
}

.about-btcs .arrow-list li.medium-txt {
    line-height: 20px;
}

.reference-section a {
    pointer-events: none;
    color: #4A4A4A;
}

#os-mutation-status {
    margin-top: -30px;
}

.mtop_20 {
    margin-top: 20px;
}

.mbottom_20 {
    margin-bottom: 20px;
}
.btc-hcp p.box-heading {
    margin-top: -31px;
    padding: 0 10px 0 40px;
}
.box-image.box-image-5-YEAR sup{
	font-size: 75%;
}
.box-image.box-image-disconti p.box-heading {
    max-width: 584px;
}
.reference-section{
    color: #555555;
}
.subpage-banner {
    background-image: url(/content/dam/website-services/us/434-imfinzi-com/btc-hcp/btc-subpages/desktop/btc-hcp-ef.jpg);
    background-size: 100% 100%;
    background-repeat: no-repeat;
    height: 115px;
    background-position: center center;
    margin: 0;
}

.sunbanner-sec {
    max-width: 722px;
    margin: 0 auto;
    padding-top: 7px;
}

.subbanner-flex {
    display: inline-flex;
    width: 100%;
    position: relative;
    align-items: center;
    justify-content: center;
}

.additional-analyses .arrow-list li {
    line-height: 20px;
}

/* update */
.safety.btc-hcp ul.arrow-list {
    padding-right: 0;

}

.dosing.btc-hcp ul#no-icon-margin li {
    position: relative;
}

.dosing.btc-hcp  ul#no-icon-margin {
    margin-left: 0;
    padding-left: 25px;
}

.dosing.btc-hcp ul#no-icon-margin li:after {
    content: '';
    background: url(/content/dam/website-services/us/434-imfinzi-com/hcc-hcp/hcc-subpages/list-arrow.svg) no-repeat;
    position: absolute;
    width: 19px;
    height: 11px;
    top: 6px;
    left: -25px;
}


.subpage-banner .banner-subhead-block hr {
    margin: 10px auto;
    width: 50px;
}

.subpage-banner p.banner-subhead {
    margin: 4px 5px;
    font-size: 12px;
    line-height: 11px;
    font-family: 'SolexOT-Regular';
    color: #003865;
}

.banner-subhead-block hr {
    background: #003865;
}

.subpage-banner .banner-subhead-block {
    width: auto;
    align-items: center;
}

.banner-liv-img img {
    max-width: 108px;
}

p.banner-heading {
    text-align: center;
    letter-spacing: -1.08px;
    line-height: 47px;
    font-size: 54px;
    font-family: 'Solex-Bold';
    color: #9E2A33;
    margin-bottom: 0px;
}

.page-content {
    max-width: 722px;
    margin: 0 auto;
}

.sec-header-container.no-barline {
    border-top: transparent;
    margin-top: 2px;
}

.sec-header {
    font-size: 15px;
    line-height: 18px;
    font-family: 'RobotoCondensed-Bold';
    background: #003865;
    color: #ffffff;
    padding: 4px 11px 6px 9px;
    border-bottom-left-radius: 8px;
    border-bottom-right-radius: 8px;
}

p.eyebrow-txt {
    font-size: 13px;
    font-family: 'RobotoCondensed-Regular';
    line-height: 15px;
    color: #003865;
}

.btc-hcp.efficacy .text-enlarge {
    /* font-family: 'Ubuntu';
      font-weight: 500;
      font-size: 18px; */
    font-family: 'Ubuntu';
    font-weight: 600;
    font-size: 19px;
    line-height: 21px;
    letter-spacing: -0.57px;
    color: #003262;
}

.data-comp-bottom.data-grey-txt p .text-enlarge, .data-comp-bottom.data-grey-txt p .txt-hr-light {
    color: #6d6f72;
}

.img-space {
    padding: 20px 10px;
}

.overall-survival-sec p.eyebrow-txt {
    margin: 30px 0 -10px;
}

.adverse-reactions-sec .eyebrow-txt {
    margin-bottom: -10px;
}

h1.heading {
    color: #9E2A33;
    font-family: 'Ubuntu';
    font-size: 25px;
    letter-spacing: 0.1px;
    line-height: 28px;
}

h1.heading sup {
    top: -0.3em;
}

.about-btcs #txt-heading {
    padding-left: 0px;
}

.analysis-sec {
    display: inline-flex;
    width: 100%;
    justify-content: space-around;
    padding: 10px 0 0px;
    margin-bottom: 15px;
    position: relative;
}

.additional-analyses sup {
    top: -0.4em;
}

.analysis-sec hr {
    width: 90%;
    height: 1px;
    margin: 0 20px;
    border-bottom: 1px solid #555555;
    position: absolute;
    bottom: 0;
}

.analysis-sec p {
    font-size: 26px;
    line-height: 30px;
    font-family: 'SolexOT-Bold';
    letter-spacing: -0.41px;
}

.data-sec-fbig {
    font-size: 20px;
}

.progression-free-survival-sec .analysis-left .data-btn-algn {
    top: -2px;
}

.data-btn-algn {
    position: relative;
    top: -3px;
}

.overall-survival-sec .data-btn-algn {
    /*top: -2.5px;*/
    top: -1.7px;
}

.progression-free-survival-sec .analysis-right .data-btn-algn {
    top: -2px;
}

.dot-btn-algn {
    top: 2px;
    position: relative;
}

.analysis-right p {
    color: #6f7175;
}

.analysis-sec p span.sot-reg {
    font-size: 15px;
    line-height: 19px;
    letter-spacing: -0.15px;
}

.sot-reg {
    font-family: 'SolexOT-Regular';
}

.analysis-right p span.sot-reg {
    letter-spacing: -0.04px;
}

.analysis-sec p span.ff-rr {
    font-size: 13px;
    line-height: 18px;
    font-family: 'Roboto-Regular';
    display: block;
}

.red-lined {
    display: inline-flex;
    width: 100%;
}

.red-lined hr {
    height: 1px;
    background: #AC182E;
    width: 30%;
    margin: 10px auto;
}

.hr-footnote p, .os-pfs-head p {
    color: #03315D;
    font-size: 13px;
    line-height: 19px;
    font-family: 'HelveticaNeueLTStd-LtCn';
    text-align: center;
}

.overall-survival-sec .hr-footnote p, .progression-free-survival-sec .hr-footnote p {
    padding-bottom: 10px;
    color: #000000;
    font-size: 17px;
    margin: 0 auto;
}

.analysis-sec img {
    margin-top: 7px;
}

.btc-hcp.efficacy .box-heading b {
    font-weight: 900;
}
/* .list-sec.list-sec-sovrl .arrow-list li:before {
    top: 5px;
} */
.arrow-list li:before{
    top: 5px !important;
}
.hr-footnote b, .os-pfs-head p b {
    font-family: 'HelveticaNeueLTStd-BdCn';
}

.list-sec {
    margin: 23px auto;
}
.real-world-evidence .list-sec {
    margin-top: 15px;
    margin-bottom: 42px;
}
.real-world-evidence .list-sec {
    margin-top: 15px;
}
.bullet-list {
    padding-left: 20px;
}

.hypenated-list, .bullet-list {
    position: relative;
}

.hypenated-list li, .bullet-list li {
    list-style-type: none;
}

.bullet-list li, .hypenated-list li {
    font-size: 16px;
    line-height: 20px;
    font-family: 'Roboto-Light';
    color: #555555;
    padding-bottom: 5px;
}

.bullet-list li::before {
    content: '\2022';
    position: absolute;
    color: #00b09b;
    font-size: 2.5em;
    left: -0.1em;
}

.callout-sec p {
    font-size: 16px;
    line-height: 22px;
    font-family: 'Roboto-Bold';
    margin: 15px 10px;
    color: #003865;
    letter-spacing: -0.32px;
}

.callout-sec {
    border: 1px solid #74A9D9;
    border-left: 16px solid #9E2A33;
}

.cta-blk-link a {
    color: #4678B0;
    font-size: 16px;
    line-height: 20px;
    font-family: 'Roboto-Light';
    text-decoration: underline;
}

.cta-blk-link {
    margin: 25px 0px 20px;
}


/* update 76790 */

.no-cell {
    display: none;
}

.extended-text {
    display: block;
    width: 300%;
}

.page-content {
    max-width: 722px;
    margin: 0 auto;
}


p.eyebrow {
    margin-top: 30px;
    margin-bottom: -25px;
    color: #003865;
    font-weight: 500;
    font-size: 18px;
}
.progression-free-survival-sec .page-content p.eyebrow {
    font-size: 16px;
    line-height: 25px;
}
p.footnotes {
    margin-bottom: 3px;
    font-size: 14px;
    line-height: 16px;
    color: #4A4A4A;
    font-family: 'Ubuntu';
    text-indent: 0;
}

.pr-0 {
    padding-right: 0 !important;
}

.mb-10 {
    margin-bottom: 10px !important;
}

.box-light-blue {
    color: #7099D3 !important;
}

.rate-box-block {
    display: flex;
    justify-content: center;
    align-items: center;
}

.rate-box {
    display: flex;
    align-items: center;
}

.rate-box p {
    color: #003262;
    font-weight: 500;
    font-size: 16px;
    line-height: 20px;
    position: relative;
    left: -12px;
    letter-spacing: -0.4px;
}

.color-grey {
    color: #7b7b7b !important;
}

.box-image.box-light-blue {
    border: 0.5px solid #03315D !important;
    margin: 50px 10px 30px 22px;
    margin-top: 43px;
}

.immune-mediated .page-content h2 {
    margin: 30px auto;
    padding: 0;
}

.immune-mediated .arrow-list li {
    margin-bottom: 3px;
    line-height: 20px;
    left: -4px;
}

.ftnt1 {
    letter-spacing: -0.27px !important;
    margin: 10px 0 15px;
}

.ftnt2 {
    letter-spacing: -0.17px !important;
    margin: 10px 0 15px;
}
p.footnotes.ftnt4 {
    margin-left: 10px;
    text-indent: -5px;
    letter-spacing: -0.1px;
}
p.footnotes.ftnt5 {
    text-indent: -8px;
    margin: 15px -5px 15px;
    letter-spacing: -0.16px;
}
p.footnotes.ftnt6 {
    text-indent: -6px;
    margin: 15px auto 20px;
}
p.footnotes.ftnt7 {
    text-indent: -6px;
    margin-left: 10px;
}
.box-image.box-image-topaz img.desktop-only {
    margin: 0 -14px;
    padding: 0 12px 0 8px;
}
.ftnt-topaz {
    /* margin: 20px -7px 0 -7px; */
    margin: 20px -7px 5px -6px;
}
.ftnt-topaz p.footnotes {
    letter-spacing: -0.41px;
}
.footnote-key-base {
    margin-left: 11px;
    margin-bottom: 15px;
}
.box-image.box-survival.mb-20 {
    margin-bottom: 20px;
}
hr.vs-line.vs-line1 {
    width: 100%;
    padding: 0;
    border-color: #a2a2a2;
}
.mt0 {
    margin-top: 0 !important;
}
.box-image-primary-progession hr.vs-line {
    width: 100%;
    padding-right: 0;
    padding-left: 0;
}

.box-light-blue:before, p.box-heading.box-light-blue:before {
    /* content: ''; */
    content: none;
    background: url(/content/dam/website-services/us/434-imfinzi-com/btc-hcp/home/Dark%20Blue%20Arrow.png) no-repeat !important;
    background-size: cover !important;
}

p.box-heading.box-light-blue {
    background: #003262;
    color: #fff !important;
    font-size: 16.5px;
    line-height: 22px;
    padding: 3px 27px 3px 10px !important;
    clip-path: polygon(0 0, 100% 0, 100% 0%, 96.5% 100%, 0 100%, 0% 0%);
    -webkit-clip-path: polygon(0 0, 100% 0, 100% 0%, 96.5% 100%, 0 100%, 0% 0%);
    position: relative;
    left: -22px;
    top: -4px;
}

.red-txt {
    font-weight: 500 !important;
}

.txt-hr-light {
    font-weight: 200;
}

.vs-line {
    border-top: 1.5px solid #003262;
    padding: 5px;
    width: 92%;
}

.data-compare {
    display: flex;
    justify-content: space-evenly;
    width: 54%;
    margin: 0 auto 10px;
    align-items: center;
    text-align: center;
}

.data-comp-vs {
    padding: 0 20px;
}

.data-comp-bottom.data-grey-txt {
    color: #707070;
}

p.data-num {
    text-align: center;
    margin-bottom: 0;
}

.nccn-expanded-text {
    padding-top: 30px;
    padding-right: 10px;
}


.nccn-expanded-text p {
    margin-bottom: 0px;
    font-family: 'Ubuntu', sans-serif;
    color: #003262;
    font-size: 15px;
    line-height: 17px;
    margin-left: 15px;
    font-weight: 400;
}

.preferred-text {
    font-size: 14px;
    font-family: 'Ubuntu', sans-serif;
    font-weight: 900;
}

.nccn-category-text {
    font-size: 17px;
    color: #003262;
    font-family: 'Ubuntu', sans-serif;
    padding: 11px;
    line-height: 13px;
    padding-top: 44px;
}

.category-text {
    font-size: 13px;
    font-weight: 700;
    font-family: 'Ubuntu', sans-serif;
    width: 83px;
    display: inline-block;
}

.ncc-bold {
    font-weight: 700;
    font-size: 28px;
    font-family: 'Ubuntu', sans-serif;
}

.nccn-category-bar {
    display: flex;
    border-top: 1px solid #707070;
    border-bottom: 1px solid #707070;
    background-color: #7099D326;
    position: relative;
    height: auto;
    margin-left: auto;
    margin-right: auto;
    margin-bottom: 50px;
    margin-top: -50px;
    right: 3px;
    padding-left: 10px;
}

.img-box-padding {
    padding-top: 10px;
    padding-bottom: 10px;
}

.mt50 {
    margin-top: 50px !important;
}
.real-world-evidence .reference-section sup {
    top: -0.5em;
    font-size: 9px;
}
.immune-mediated ul.arrow-list {
    padding-right: 0;
}

.about-btc ul.dropdown-menu.multi-level {
    display: none !important;
}

.about-btcs .page-heading {
    padding: 25px 0 30px;
}

/* .box-image.box-image-5-YEAR img {
    margin: 25px auto;
  } */
.sd-and-pc p.eyebrow {
    margin-top: 0;
    margin-bottom: 0;
}

.efficacy.btc-hcp .cta-sec p, .callout p {
    color: #AC182E !important
}

.efficacy.btc-hcp .arrow-list li {
    line-height: 20px;
}

.efficacy.btc-hcp .overall-survival-sec .arrow-list li {
    letter-spacing: -0.16px;
}

.btc-hcp .ef-anchor-sec {
    margin: 0 auto 20px;
    max-width: 722px;
    display: flex;
    flex-direction: row;
}

.btc-hcp.efficacy .eff-j1::after {
    top: 0px;
    left: 0px;
}

.btc-hcp.efficacy .eff-j2::after {
    top: 0px;
    left: 0px;
}

.btc-hcp .ef-anchor-sec>a {
    font-size: 14px;
    line-height: 16px;
    font-weight: 700;
    color: #003865;
    background: #EBF1F8;
    padding: 10px;
    margin-right: 4px;
    height: 50px;
    width: 160px;
    text-align: center;
    display: flex;
    justify-content: center;
    align-items: center;
}

.btc-hcp .ef-anchor-sec a:after {
    content: '\f078';
    font-family: fontawesome;
    font-weight: 100;
    color: #AC182E;
    position: relative;
    left: 25px;
}

p.disclaimer-eyebrow {
    color: #4A4A4A;
    font-size: 16px;
    font-weight: 600;
    padding-top: 20px;
    margin: 0px;
    line-height: 20px;
}
h2.sub-head-topaz.sub-head-topaz-txt1 {
    letter-spacing: -0.3px;
}
.box-image.pb-0.box-image-space {
    margin-top: 35px;
}
.sub-head-topaz {
    font-size: 22px !important;
    font-weight: 400 !important;
    padding-top: 0 !important;
    line-height: 25px !important;
    letter-spacing: -0.1px;
}

.callout.callout-red:before {
    background: url(/content/dam/website-services/us/434-imfinzi-com/hcc-hcp/hcc-subpages/callout-arrow-red.svg) no-repeat;
}

#subhead-safety {
    margin-top: 15px;
    font-weight: 400;
}

p.disclaimer-eyebrow a {
    color: #555555;
    text-decoration-line: underline;
}

div#dosing-box-1 {
    padding-bottom: 0px !important;
}

p#dosing-box {
    margin-top: -30px;
}

p#box-heading-1 {
    margin-top: -30px;
}
.box-image.box-image-sd .box-heading.bh-os {
    padding-left: 30px;
}
.rw-evidence ul.arrow-list {
    padding-right: 0;
}

.treatment-modifications-sec ul.arrow-list {
    padding-right: 0;
    padding-bottom: 15px;
}

.treatment-modifications-sec .list-sec {
    margin: 14px auto;
}

.treatment-modifications-sec .list-sec li {
    line-height: 20px;
    margin-bottom: 7px;
}

.treatment-modifications-sec .arrow-list li:before {
    top: 4px;
}

.list-sec.box-ullist {
    margin-bottom: 15px;
    margin-top: 20px;
}

.list-sec.box-ullist ul.arrow-list {
    margin: 0;
    padding-right: 0;
}
.list-sec.box-ullist ul.arrow-list li {
    line-height: 20px;
}
.box-image.box-image1 img {
    /* margin: 40px 0 25px; */
    margin: 40px 5px 25px;
}
.box-image.box-image1.box-image-space.box-image-rwe img.desktop-only {
    margin: 15px 5px 25px;
}
.ds-prep-str-ad .callout.callout-red p {
    padding: 12px 0px 12px 55px;
    letter-spacing: 0.01px;
}

.box-footenote {
    font-size: 14px;
    line-height: 16px;
    color: #4a4a4a;
    letter-spacing: 0.03px;
    font-weight: 100;
    text-indent: -7px;
    margin-bottom: 15px;
}

.box-image.box-image1.box-image-space .box-footenote{
	text-indent: -5px;
	margin-bottom: 5px;
}
.ftnote-rwe-sd {
    margin-left: 7px;
    padding-right: 4px;
}
.box-image-sd .mid-content {
    padding: 20px 0;
}

.box-image-sd p {
    font-size: 17px;
    line-height: 19px;
    font-weight: 500;
    color: #003262;
    margin-bottom: 12px;
}

span.grey-text {
    color: #707070;
}

.box-image-sd .blue-text p {
    font-size: 19px;
    line-height: 21px;
    letter-spacing: -0.57px;
    margin-bottom: 10px;
}

.box-image-sd .blue-text p span.light, .box-image-sd .grey-text p span.light {
    display: inline-block;
    font-size: 14px;
    line-height: 21px;
}

.box-image-sd .month-wrapper img.vs {
    width: 22px;
}

.box-image-sd p.hr-txt {
    color: #4a4a4a;
    font-size: 17px;
    line-height: 17px;
    letter-spacing: -0.51px;
    margin-bottom: 0;
}

.box-image-sd hr {
    max-width: 555px;
    border-color: #707070;
    margin: 15px auto;
}

.prescribing-info {
    font-size: 16px;
    color: #555555;
    font-weight: 600;
}

.prescribing-info a {
    color: #7099D3;
    text-decoration: underline;
}

.mid-content {
    text-align: center;
}

.month-wrapper {
    margin: 0 auto;
    max-width: 345px;
    display: flex;
    justify-content: space-between;
    align-items: center;
}
.month-wrapper.month-wrapper-sd {
    max-width: 480px;
}
.month-wrapper.month-wrapper-sd .grey-text .bold {
    font-size: 19px;
    line-height: 21px;
    color: #6d6f72;
}
.month-wrapper.month-wrapper-sd .grey-text .light {
    color: #6d6f72;
}
.ds-prep-str-ad ul.arrow-list {
    margin-left: 30px;
    margin-top: 20px;
}
ul.arrow-list.pr-0.arrow-list-rwe {
    margin-left: 20px;
}
.ds-prep-str-ad li {
    line-height: 20px;
}

ul#no-icon-margin {
    margin-left: 0;
}

#eyebrow-dosing {
    font-size: 18px !important;
}

#subhead-dosing {
    font-size: 20px !important;
    margin-top: -10px !important;
    color: #003262;
}

.blank-img-box img {
    margin: 0 auto;
}


.two-columns-txt-btc {
    display: flex;
    justify-content: space-between;
}

.column-txt-btc {
    flex-basis: 48%;
}

.about-btcs.btc-hcp .medium-txt {
    font-weight: 500;
}

.about-btcs.btc-hcp ul.light-txt {
    padding-left: 80px;
}

.about-btcs.btc-hcp .light-txt li {
    line-height: 10px;
}

.about-btcs.btc-hcp .light-txt li::before {
    top: -8px;
    left: -15px;
    content: '_';
}

.about-btcs.btc-hcp .hypen-list.light-txt li::before {
    top: -2px;
}

.about-btcs.btc-hcp .section-heading span {
    background: #7B7B7B;
    padding: 7px 11.5px;
    position: relative;
    top: 1px;
}

.about-btcs.btc-hcp .section-heading {
    border-top: 1px solid #7B7B7B;
}

.box-image.box-image-tbl-dosing .table-block {
    max-width: 680px;
    margin: 40px auto 25px;
}

.box-image.box-image-tbl-dosing {
    padding: 20px 8px 30px 13px !important;
    max-width: 710px;
    margin-left: 24px;
}

.box-image.box-image-tbl-dosing p.footnotes {
    letter-spacing: -0.27px;
    font-family: 'Ubuntu', sans-serif;
}

.ds-prep-str-ad.ds-prep-str-ad-1 ul.arrow-list {
    padding-left: 0;
    padding-right: 44px;
    margin-left: 20px;
    margin-top: 0;
}

.prep-blck li:before, .storage-blck li:before {
    content: none !important;
}

h2.heading.heading-prep {
    margin: 0 0 20px;
    color: #003262;
}

h2.heading.heading-storage {
    margin: 0;
    padding-bottom: 0;
    color: #003262;
}

.arrow-list.arrow-list-storage {
    margin-bottom: 25px;
}

h2.heading.heading-admin {
    margin: -12px 0 25px;
    padding: 0;
}

.storage-blck h2 {
    color: #003262 !important;
}

.heading.heading-dosag {
    margin: 10px 0 25px;
    padding: 0;
    color: #003262;
}

.ds-prep-str-ad-1 ul.arrow-list li {
    line-height: 20px;
}

.list-sec.list-sec-3yr {
    margin-bottom: 15px;
}

.list-sec.list-sec-3yr ul.arrow-list {
    padding-right: 0;
}

.list-sec.list-sec-3yr ul.arrow-list li {
    color: #555555;
    font-weight: 600;
}

p.footnotes.ftnt3 {
    text-indent: -7px;
    font-weight: 300;
    padding-right: 26px;
    margin-bottom: 2.5rem;
}

.box-image p.footnotes.ftnt3{
    padding: 0;

}

span.add-ana-txt-blue {
    color: #003466;
    font-weight: 500;
}
.add-ana-txt-blue-bold{
    color: #003466;
    font-weight: 700;
}

span.add-ana-txt-red {
    color: #AC182E;
    font-weight: 500;
}

span.add-ana-txt-gray {
    color: #555555;
    font-weight: 700;
}

.additional-analyses h2.sub-head-topaz {
    margin-top: 0px;
    padding-top: 0px;
    margin-bottom: 0px;
    padding-bottom: 0px;
}

.additional-analyses .ef-anchor-sec a:after {
    content: '\f078';
    font-family: fontawesome;
    font-weight: 100;
    color: #AC182E;
    position: relative;
    left: 3px;
    top: 0px;
}


.btc-hcp .ef-anchor-sec>a {
    font-size: 13px;
}

a.add-ana-j3:after {
    position: relative;
    top: 10px;
}

.add-ana-j3 {
    padding-top: 15px !important;
}

.eff-j1::after {

    top: 10px;
}

.eff-j2::after {

    top: -6px;
}

span.big-txt {
    font-size: 17px;
}

#txt-nowrap-2 {
    white-space: nowrap;
}

h2#\#subhead-safety {
    margin-top: 0 !important;
    margin-bottom: 0 !important;
    padding-bottom: 0;
}

.additional-analyses .mtop-1rem {
    margin-top: -1rem !important;
}

.safety .box-image {
    margin: 50px auto 30px;
}

.ds-btc td:first-child, th:first-child {
    text-align: left;
    border-left: none;
    /* border-right: 1px solid #707070; */
    padding-left: 1rem;
}


.ds-btc th:nth-child(2) {
    border-right: 1px solid #707070;
}

.ds-btc th:nth-child(2), .ds-btc th:nth-child(3) {
    text-align: left;
    padding-left: 1rem;
}

.ds-btc th:nth-child(2), .ds-btc th:nth-child(3) {
    text-align: left;
    padding-left: 1rem;
}

.ds-btc .span-row td {
    color: #003262;
}

.ds-btc .span-row, .ds-btc .span-row td {
    background: #b5cef2;
}
span.br-txt {
    display: inline-block;
    margin: 8px 0;
}
.ds-btc td.blue-row {
    background: #E8F1F7;
}

.ds-btc td, .ds-treat th {
    white-space: normal;
    text-align: left;
    padding: 7px 10px;
    line-height: 18px;
}


.ds-btc table tr:last-child td {
    border-bottom: 1px solid #707070;
}

.tb-txt-indent {
    text-indent: 10px;
    display: block;
}

td.red-f-cell, th.red-f-cell {
    color: #AC182E;
}


.hr-scroll-txt p {
    font-weight: 700;
    font-size: 14px;
    line-height: 16px;
    letter-spacing: 0.03px;
    position: relative;
}

.eff-table-pat-ch th:first-child {
    padding: 0px;
    width: 250px;
}

.box-image-adverse-reac .img-box-padding {
    padding-top: 20px;
    padding-bottom: 20px;
}

/* update 76790 end */



.data-red-txt, .data-red-txt p {
    /* color: #AC182E;
   text-align: center; */

    font-weight: 300;
    letter-spacing: -0.42px;
    font-size: 14px;
    line-height: 21px;
    color: #003262;
    margin-bottom: 0;
}
p.color-red, p.color-red .text-enlarge {
    color: #AA212B !important;
}
.ef-anchor-sec a {
    font-size: 14px;
    line-height: 16px;
    font-weight: 700;
    color: #003865;
    background: #EBF1F8;
    padding: 13.5px 19px;
}

.ef-anchor-sec a:after {
    content: '\f078';
    font-family: fontawesome;
    padding-left: 5px;
    font-weight: 100;
    color: #AC182E;
}

.ef-anchor-sec a.anchor-up:after {
    content: '\f077';
}

.ef-anchor-sec a:hover {
    color: #ffffff;
    background: #003262;
    text-decoration: none;
}

.ef-anchor-sec a:hover:after {
    color: #ffffff;
}

/* .percentage-number {
   font-size: 32px;
   font-weight: 900;
  } */
.reduction-text {
    font-family: 'Ubuntu', sans-serif;
    font-size: 18px;
    line-height: 20px;
    color: #AA212B;
    text-align: center;
    margin-top: 28px;
    font-weight: 900;
    margin-bottom: 30px;
    letter-spacing: -0.54px;
}


.percentage-number {
    font-size: 26px;
    font-weight: 600;
    line-height: 22px;
    letter-spacing: -0.78px;
}

.reduction-text1.reduction-text1 {
    font-family: 'Ubuntu', sans-serif;
    font-size: 17px;
    line-height: 22px;
    color: #003262;
    text-align: center;
    margin-top: 28px;
    font-weight: 600;
    margin-bottom: 0;
    letter-spacing: -0.51px;
}

.reduction-text sup.per-top.per-top-sft {
    top: -.5em;
}

p.reductxt {
    text-align: center;
    font-size: 17px;
    line-height: 24px;
    letter-spacing: -0.51px;
    color: #003262;
    font-weight: 500;
    margin-top: 4px;
}

.reductxt span.gray-txt {
    color: #6d6f72;
    font-weight: 500;
}



.reduction-text.customMargin {
    margin-bottom: 6px;
}

span.gray-txt {
    color: #707070;
    font-weight: normal;
}

.hr-text {
    color: #AC182E;
    font-family: 'Ubuntu', sans-serif;
    line-height: 14px;
    text-align: center;
    font-size: 12px;
    margin-bottom: 6px;
    margin-top: 3px;
    font-weight: 500;
}

.box-image-primary-progession p.reductxt {
    line-height: 20px;
}
.box-image-primary-progession .data-compare {
    width: 80%;
    margin: 20px auto -3px;
}

/* 
  
  .nccn-blck {
   border-top: 1px solid #74A9D9;
   border-bottom: 1px solid #74A9D9;
   display: inline-flex;
   padding: 16px 0px 10px;
   margin-bottom: 20px;
   align-items: center;
  }
  .nccn-blck p {
   color: #003466;
   font-size: 16px;
   line-height: 19px;
   font-family: 'RobotoCondensed-Regular';
   letter-spacing: -0.32px;
  }
  p.nccn-txt {
   font-size: 50px;
   font-family: 'RobotoCondensed-Bold';
   margin-right: 10px;
  }
  span.nccn-subtxt {
   font-size: 14px;
   display: block;
   margin-top: 10px;
   letter-spacing: 0.3px;
  } */

.table-heading p, .rd-compare-sec .table-heading p {
    color: #0F3763;
    font-size: 17px;
    line-height: 19px;
    font-family: 'RobotoCondensed-Bold';
    margin: 0 5px;
    text-align: center;
}

.table-heading hr {
    width: 24%;
}

.ef-stud-bullet-sec-1 p.bullet-heading {
    margin-bottom: 27px;
}

/* p.footnotes {
   margin-bottom: 3px;
   font-size: 14px;
   line-height: 16px;
   color: #4A4A4A;
   font-family: 'Ubuntu';
  } */
.ef-OS-Forrest-Plot-Chart {
    margin: 25px auto 50px;
}

.ef-OS-Forrest-Plot-Chart .table-heading {
    margin-bottom: 20px;
}

.subhead {
    color: #003865;
    font-size: 16px;
    line-height: 20px;
    font-family: 'Roboto-Bold';
}

.main-txt {
    color: #6f7175;
    font-family: 'ubuntu';
    font-size: 18px;
    text-align: center;
    margin: 20px auto 10px;
}

.sec-header-container {
    border-top: 1px solid #003865;
    padding-top: 3px;
}

.progression-free-survival-sec .sec-header-container {
    margin: 25px 0;
}

.progression-free-survival-sec .table-heading hr {
    width: 21%;
}

.pfs-Chart {
    margin: 0px auto 15px;
}

.progression-free-survival-sec .callout-sec {
    margin-bottom: 25px;
}

.ef-dor-Chart {
    margin: 25px auto 35px;
}

.ef-dor-Chart .table-heading {
    margin-bottom: 15px;
}

.ef-orr-Chart {
    margin-right: 50px;
}

.ef-orr-Chart .table-heading hr {
    width: 15%;
}

.ef-dor-Chart .table-heading hr {
    width: 18%;
}

.ef-mtr-Chart .table-heading hr {
    width: 23%;
}

.ef-key-patient-char-table .table-heading hr {
    width: 31%;
}

.ef-orr-mtr-img-sec {
    display: inline-flex;
}

.ef-mtr-Chart img {
    margin: 0px auto 10px;
    width: 100%;
}

.ef-orr-mtr-img-sec .table-heading p {
    text-align: center;
}

.ef-orr-mtr-img-sec>div {
    width: 50%;
}

.ef-mtr-Chart .footnotes {
    margin-top: 26px;
}

.ef-bullet-img-blck, .ef-bullet-bullet-blck {
    display: inline-flex;
    width: 100%;
}

.ef-stud-eligibility-section {
    border-top: 1px solid #74A9D9;
    border-bottom: 1px solid #74A9D9;
    padding: 20px 0px 30px;
    margin: 20px auto;
}

.ef-bullet-img-blck {
    padding-bottom: 30px;
    margin-bottom: 26px;
    align-items: center;
}

p.bullet-heading {
    color: #0F3763;
    line-height: 29px;
    font-size: 21px;
    font-family: 'RobotoCondensed-Bold';
}

.sd-and-pc .sec-header-container {
    margin: 57px auto 30px;
}

.ef-stud-bullet-sec-1, .ef-stud-bullet-sec-2 {
    width: 40%;
}

/* .sd-and-pc .page-content :nth-child(11) {
   margin: 55px auto 20px;
  } */
.ef-key-patient-char-table .red-lined.table-heading {
    margin: 30px auto;
}

.sd-and-pc .callout-sec {
    margin: 35px auto 0px;
}

.adverse-reactions-sec .table-heading {
    margin: 25px auto 30px;
}

.adverse-reactions-sec .table-heading hr {
    width: 20%;
}

.OS-KM-Curve-Chart.chart-img img.desktop-only {
    margin-bottom: 15px;
}

/*table design*/
table {
    border-collapse: collapse;
    border-spacing: 0;
    width: 100%;
    margin: 0 auto;
}

.customTable th, .customTable td {
    padding: 1.5px 8px;
    text-align: center;
    color: #ffffff;
}

.customTable th {
    font-family: 'HelveticaNeueLTStd-BdCn';
    letter-spacing: 0.03px;
    font-size: 16px;
    line-height: 19px;
    padding: 3px 8px;
}

.bg-red-cell {
    background: #A2192A;
}

.bg-grey-cell {
    background: #85868A;
}

.bg-blue-cell {
    background: #03315D;
}

th.bg-white-cell {
    background: #ffffff;
    color: #03315D;
}

.customTable td:nth-child(1) {
    text-align: left;
    border-left: none;
}

.customTable td.chart-body, .customTable td.span4 {
    border-left: none;
}

.customTable td {
    border: 1px solid #7099D3;
    border-right: none;
    color: #2B2E34;
    font-size: 16px;
    line-height: 22px;
    font-family: 'HelveticaNeueLTStd-LtCn';
}

td.chart-body, td.chart-body-copy {
    letter-spacing: -0.1px;
}

td.span4 {
    background-color: #E8F1F7;
    border-top: 1px solid #7099D3;
    color: #03315D;
    font-size: 16px;
    line-height: 22px;
    font-family: 'HelveticaNeueLTStd-BdCn';
}

td.chart-body.chart-indent {
    text-indent: 10px;
}

.sf-treat-modi-table .desktop-only td.chart-body-copy {
    text-align: left;
}

.sf-treat-modi-table .mobile-only td {
    text-align: center;
}

.sf-treat-modi-table .table-section {
    margin: 30px 0 10px;
}

.sf-treat-modi-table .customTable.desktop-only td.chart-body-copy {
    border-left: 0.5px solid #7099D3;
}

.sf-treat-modi-table .chart-body b {
    font-family: 'HelveticaNeueLTStd-BdCn';
}

/*Switch page section design*/
.switch-section {
    margin: 40px auto 10px;
    display: inline-flex;
    width: 100%;
    justify-content: space-between;
    position: relative;
}

.switch-section a {
    color: #173A64;
    font-family: 'Ubuntu';
    font-size: 20px;
    line-height: 19px;
    padding: 30px 50px;
}

.switch-section a:before {
    background: url(/content/dam/website-services/us/434-imfinzi-com/btc-hcp/btc-subpages/desktop/page-switch-icon.png) no-repeat;
    content: '';
    width: 32px;
    height: 32px;
    position: absolute;
    left: 0;
    top: 22px;
}

.switch-section a.switch-after:before {
    right: 0;
    left: auto;
    transform: rotate(180deg);
}

.customTable th.chart-col-heading {
    border: 1px solid #7099D3;
    border-right: none;
    color: #03315D;
    font-size: 16px;
    line-height: 19px;
    font-family: 'RobotoCondensed-Bold';
}

.efficacy h1.heading {
    margin-bottom: 20px;
}

.sf-ar-table th.bg-red-cell, .sf-ar-table th.bg-grey-cell,
.sf-lab-abnormalities-table th.bg-red-cell, .sf-lab-abnormalities-table th.bg-grey-cell {
    padding: 10px 8px;
}

.sf-ar-table td.chart-body-copy {
    width: 120px;
}

.discontinuation-rates-sec .sec-header-container {
    margin: 50px auto 25px;
}

.dis-rate-section {
    border: 1px solid #7099D3;
    padding: 10px 30px 10px 30px;
}

.dis-rate-section p {
    text-align: center;
}

.dis-rate-comp {
    display: inline-flex;
    width: 100%;
    justify-content: center;
    font-family: 'SolexOT-Bold';
    margin: 5px auto;
}

.ef-immune-mediated-ar h1 {
    margin: 31px auto 20px;
}

.dis-rate-comp p {
    font-size: 35px;
    line-height: 43px;
    letter-spacing: -0.59px;
    padding-left: 40px;
    color: #6F7175;
}

.dis-rate-comp .small-font {
    font-size: 39px;
}

.dis-rate-comp .red-txt .data-btn-algn {
    top: -3px;
    font-size: 35px;
}

.dis-rate-comp p.red-txt {
    border-right: 2px solid #7099D3;
    padding-right: 40px;
    padding-left: 0px;
    color: #A2192A;
}

.dis-rate-comp p span.sot-reg {
    font-size: 16px;
    line-height: 20px;
    letter-spacing: -0.05px;
}

p.red-txt span.sot-reg {
    color: #BA2527;
}

.red-txt .ff-rr {
    color: #9E2A33;
}

.analysis-right .ff-rr {
    color: #555555;
}

.ef-immune-mediated-ar .sec-header-container {
    margin: 60px auto 30px;
}

.hypenated-list li:before {
    content: '—';
    color: #1EAE9A;
    font-size: 16px;
    line-height: 12px;
    font-family: 'Roboto-Bold';
    left: 20px;
    position: absolute;
    top: 5px;
}

.sf-lab-ab .sec-header-container {
    margin: 30px auto;
}

.sf-lab-abnormalities-table .table-heading {
    margin: 10px auto 30px;
}

.sf-lab-abnormalities-table .table-heading hr {
    width: 41%;
    margin: 20px auto;
}

.sf-lab-abnormalities-table .table-heading p {
    text-align: center;
}

th.sub-th {
    color: #2B2E34;
    font-size: 16px;
    font-family: 'HelveticaNeueLTStd-MdCn';
    line-height: 22px;
    border-left: 1px solid #7099D3;
}

.sf-ar-table {
    margin-bottom: 25px;
}

.sf-lab-abnormalities-table .customTable {
    margin-bottom: 20px;
}

.sf-lab-ab ul.bullet-list {
    margin: 20px auto 0;
}

.rd-compare-sec {
    display: inline-flex;
    width: 100%;
    margin: 15px auto 0;
}

.rd-start-with img, .rd-continue img {
    display: block;
    margin: 0 auto;
}

.rd-start-with, .rd-continue {
    width: 50%;
}

.rd-compare-sec p {
    text-align: center;
    line-height: 16px;
    font-size: 16px;
    font-family: 'Roboto-Light';
    color: #555555;
}

.rd-start-with img {
    margin-top: -18px;
}

p.rd-comp-footnote {
    font-size: 14px;
    line-height: 15px;
    font-family: 'RobotoCondensed-Light';
    color: #555555;
    margin-top: 10px;
}

.rd-start-with p.rd-comp-footnote {
    float: left;
    padding-right: 30px;
    margin-top: 0;
}

p.rd-compare-head {
    font-size: 22px;
    line-height: 24px;
    font-family: 'RobotoCondensed-bold';
    color: #000000;
    margin-top: 23px;
}

.recommended-dosage .callout-sec {
    margin: 38px auto 36px;
}

.sf-treat-modification-section {
    display: inline-flex;
}

.sf-treat-modification-section div {
    width: 50%;
}

.with-imfi-blck {
    margin-right: 15px;
}

.sf-treat-modification-section p, .sf-treat-modification-section ul.bullet-list {
    border-top: 1px solid #4678B0;
    border-bottom: 1px solid #4678B0;
    margin-bottom: 0;
    font-size: 16px;
    color: #173A64;
    padding: 5px 0px 5px 10px;
    font-family: 'RobotoCondensed-Bold';
}

.sf-treat-modification-section p span {
    color: #555555;
    font-family: 'Roboto-Regular';
    padding: 0;
}

.t-diff span.red-txt {
    color: #A2192A;
    font-family: 'RobotoCondensed-Bold';
}

span.t-diff {
    display: inline-flex;
    align-items: center;
    width: 100%;
}

span.t-diff span {
    margin: 0px 5px;
    font-size: 16px;
    line-height: 19px;
    text-align: center;
}

p.treat-last {
    color: #ffffff;
    background: #4678B0;
    text-align: center;
    padding: 15px;
}

p.treat-head {
    background: #D3E3EF;
}

.psa-sec {
    display: inline-flex;
    align-items: center;
    width: 100%;
    margin-bottom: 22px;
}

.psa-sec.top-algn-sec img {
    margin-top: -10px;
    ;
}

/* .storage-blck p {
   font-size: 16px;
   line-height: 20px;
   font-family: 'Roboto-Light';
   color: #555555;
  } */
.psa-sec img {
    margin-right: 15px;
    max-width: 57px;
}

.red-lined.table-heading.treat-head p {
    color: #A2192A;
    border: none;
    font-family: 'RobotoCondensed-Bold';
    font-size: 16px;
    line-height: 19px;
}

.red-lined.table-heading.treat-head hr {
    background: #4678B0;
    height: 1px;
}

.red-lined.table-heading.treat-head {
    width: 100%;
    align-items: center;
}

.discon-imfi-blck .red-lined.table-heading.treat-head hr {
    width: 11%;
}

.recommended-dosage p.eyebrow-txt {
    margin-top: 30px;
}

.recommended-dosage p.subhead {
    margin-top: 25px;
}

.treatment-modifications-sec p.subhead {
    margin: 20px auto 22px;
    color: #555555;
}

.sf-ebook-blck {
    border: 1px solid #7099D3;
    max-width: 450px;
    width: 100%;
    margin: 90px auto 30px;
}

.sf-ebook-blck p {
    color: #9E2A33;
    font-size: 20px;
    font-family: 'Roboto-Medium';
    line-height: 24px;
    max-width: 378px;
    margin: 0 auto 50px;
    text-align: center;
}

.sf-ebook-blck p a {
    color: #4678B0;
    text-decoration: underline;
}

.sf-ebook-blck img {
    margin: -13% auto 30px;
    display: block;
    width: 100%;
    max-width: 81px;
}

.discon-imfi-blck ul.bullet-list li {
    margin-bottom: 15px;
}

.psa-sec p {
    font-size: 16px;
    line-height: 19px;
    color: #555555;
    font-family: 'Roboto-Light';
}

.sf-treat-modification-section .bullet-list li::before {
    font-size: 1.5em;
}

.ds-prep-str-ad p.sec-header-container {
    margin: 60px auto 25px;
}

.subhead a {
    text-decoration: underline;
}

.ds-prep-str-ad .footnotes {
    margin-top: 20px;
}

a.subhead-link {
    color: #4678B0;
}

.prescribing-info a.subhead-link {
    color: #7099d3;
}

.dosing a.subhead-link:hover {
    text-decoration: none;
}

.ds-prep-str-ad h1.heading {
    margin: 20px auto;
}

.dos-blck img {
    margin-right: 10px;
}

.ef-orr-dor .sec-header-container {
    margin-top: 50px;
}

/* .sf-treat-modi-table th {
   border-right: 1px solid #ffffff;
  } */
.sf-treat-modi-table th:last-child {
    border-right: none;
}

.sf-treat-modi-table .desktop-only tr td.chart-body-copy:last-child {
    text-align: center;
}

.sf-treat-modi-table td.span4 {
    background: #ffffff;
}

.sf-treat-modi-table tr.blue-row {
    background: #E8F1F7;
}

.sf-treat-modi-table .desktop-only td.chart-body {
    white-space: nowrap;
}

hr.os-data-hr {
    width: 29%;
}

.btc-table-section {
    margin: 0 auto;
}

.sd-and-pc .btc-table-section {
    margin-bottom: 10px;
}

.ef-orr-Chart img {
    margin: 0 auto;
    display: block;
}

/*.overall-survival-sec .nccn-txt img {
   width: 100%;
  }*/

body.efficacy.btc-hcp .reference-section {
    font-weight: 400;
    padding-right: 13px;
}

.break-work {
    word-break: break-all;
}

/*body.efficacy.btc-hcp  h2#eff-head-1 + .box-image {
      margin-bottom: 50px;
  }*/

.discontinuation-rates-sec .img-box-padding+img {
    margin: -15px auto 5px !important;
}

body.safety.btc-hcp h2#\#subhead-safety sup {
    /* top: -0.45em; */
    /*font-size: 15px;*/
}

body.dosing.btc-hcp sup {
    font-size: 65%;
    top: -0.4em;
}

body.dosing.btc-hcp p.footnotes.fn-2 {
    text-indent: 2px;
    margin-top: 16px;
}

@media screen and (min-width: 768px) and (max-width: 991px) {
    .sunbanner-sec {
        padding-top: 20px;
    }
}

@media screen and (min-width: 992px) {
    /*.section-linking {
       scroll-margin-top: 127px;
   }*/

   .mb-10-d {
    margin-bottom: 10px !important;
    }

   .list-sec .arrow-list li:not(.box-image .arrow-list li) {
    left: -4px;
    line-height: 20px;
   }

   h2#dosing-subhead-2 {
    font-size: 22px;
    }

    p.disclaimer-eyebrow.dosage-space {
        margin-bottom: -10px;
    }

    p.footnotes.dosage-space {
        margin-bottom: -15px;
    }


    .about-btcs #column-txt-heading {
        font-size: 16px;
        line-height: 24px;
    }

    p.footnotes.fn-2.txt-indent-4.dosage-indent {
        text-indent: -5px !important;
        margin-left: 2px;
        margin-top: 0 !important;
        padding-right: 16px;
    }

    .sunbanner-sec {
        padding-top: 21px;
    }

    .banner-liv-img {
        position: absolute;
        left: 0;
    }

    .ef-bullet-img-blck img {
        margin-top: 60px;
    }

    .ef-bullet-img-blck {
        border-bottom: 1px solid #9C2B36;
    }

    .adverse-reactions-sec h1.heading {
        margin-bottom: 20px;
    }

    .ef-immune-mediated-ar p.subhead {
        margin-bottom: 30px;
    }

    .treatment-modifications-sec p.sec-header-container {
        margin: 68px auto 25px;
    }

    /* .recommended-dosage h1.heading {
       margin: 10px auto 20px;
   } */


    .recommended-dosage h1.heading {
        margin: 10px auto 20px;
        font-size: 24px;
        color: #AC182E;
        font-weight: 500;
        font-family: 'Ubuntu';
    }

    .dis-rate-comp p span.sot-reg {
        position: relative;
        bottom: 6px;
    }

    .analysis-sec p {
        font-size: 23px;
    }

    .data-sec-fbig {
        font-size: 20px;
    }

    .ef-orr-mtr-img-sec img {
        margin-top: 25px;
    }

    .about-btcs .about-btcs-sec .page-content>h2:nth-child(1) {
        width: 101%;
        padding-bottom: 8px;
    }

    .efficacy.btc-hcp h2#eff-head-1+.box-image .reduction-text {
        width: 102%;
        margin-left: -1.5%;
        margin-top: 17px;
    }


    body.dosing.btc-hcp .callout.dosing-box1-callout {
        display: flex;
        align-items: center;
        justify-content: center;
        height: 77px;
    }

    body.dosing.btc-hcp .dosing-box1-callout::before {
        top: 50%;
        transform: translateY(-50%);
    }

    body.dosing.btc-hcp .dosing-box1-callout p {
        padding-right: 25px !important;
    }

    body.safety.btc-hcp h2#subhead-safety {
        width: 101%;
    }

    .discontinuation-rates-sec .img-box-padding {
        padding: 0;
        /* margin: -15px auto -10px!important; */
        margin: 0 0 0 12px !important;
    }

    body.safety.btc-hcp .ef-immune-mediated-ar>.page-content h2:nth-child(1) {
        width: 104%;
    }

    .box-survival {
        padding-left: 0 !important;
        padding-right: 0 !important;
    }

    .box-survival img.desktop-only.img-box-padding {
        /* width: 100%;
          margin-left: -3px!important;
          margin-bottom: -10px; */
          padding-top: 5px;
    }
    p.reduction-text.customSize2.reduction-text1 {
        margin-top: 15px;
    }
    body.efficacy.btc-hcp .ef-orr-dor .list-sec+.box-image img {
        width: 100%;
        margin: 25px 0 20px;
    }

    body.efficacy.btc-hcp .ef-orr-dor .list-sec+.box-image {
        padding-left: 6px !important;
        padding-right: 5px !important;
    }

    body.efficacy.btc-hcp .box-image.key-table {
        padding-left: 0 !important;
        padding-right: 0px !important;
    }

    body.efficacy.btc-hcp .box-image.key-table img {
        width: 100%;
        padding:20px 3px 20px;
    }

    body.dosing.btc-hcp #dosage-txt-2+.list-sec {
        width: 102%;
    }
    .about-btcs p.box-heading, .about-btcs h2.box-heading{
        padding: 0 6px 0 35px !important;
    }
    .additional-analyses.btc-hcp p.box-heading {
        margin-top: -35px;
    }
    .pb-17 {
        padding-bottom: 17px !important;
    }
    .mt-30{
        margin-top: 30px !important;
    }
    .box-image.box-image-5-YEAR {
        margin-top: 50px;
    }
    .mt-50{
        margin-top: 50px;
    }
    .box-image.box-image-5-YEAR img.desktop-only.img-box-padding {
        margin-left: 33px;
    }
    p.footnotes.ftnt-dease {
        margin: 30px auto 5px;
    }
    p.footnotes.ftnt-dease.ftnote-ds {
        margin-bottom: 15px;
        margin-top: -5px;
    }
    .pr-30 {
        padding-right: 30px !important;
    }
    h2#eff-head-1 {
        padding-right: 1px;
    }
    .list-sec.list-sec-sovrl.mt-0 {
        margin: 10px auto 15px;
    }
    .box-image.box-image-per-ongo.box-image-per-ongo1 p.box-heading {
        margin-left: 13px;
    }
    h2.sub-head-topaz.mt--10 {
        margin-top: 0;
    }
    p.box-heading strong {
        font-size: 18px;
        font-family: 'RobotoCondensed-Bold';
    }
    p.footnotes.ftnt-time {
        margin-left: -4px;
        color: #4a4a4a;
        letter-spacing: -0.1px;
        text-align: justify;
        text-indent: -2px;
    }
    .box-image.box-image-space {
        padding: 20px 5px 10px 10px !important;
    }
    .box-image.box-image-space p.box-heading:before {
        left: -32px;
    }
    .mt-45{
        margin-top: 45px !important;
    }
    .box-image.box-image-primary-progession span.text-enlarge {
        font-size: 18px;
        line-height: 16px;
        letter-spacing: -0.54px;
    }
    .box-image.box-image-primary-progession .data-comp-top.data-red-txt p, .box-image.box-image-primary-progession .data-comp-bottom.data-grey-txt p {
        line-height: 16px;
    }
    .eyebrow.mt-25{
        margin-top: 25px;
    }
    .box-image.viral-hep img {
        margin-top: 15px;
    }
    .ds-btc.table-block.desktop-only td {
        padding: 3px 10px;
    }
    .tdht td.tb-sticky {
        padding: 10px 10px !important;
    }
    .tdht1 td.tb-sticky {
        padding: 17px 10px !important;
    }
    .tdht2 td.tb-sticky {
        padding: 10px 10px !important;
    }
    strong.gt-symbol {
        font-size: 28px;
        font-family: Roboto-bold, sans-serif;
    }
    span.gt-symbol {
        font-family: inherit;
    }
    p.footnotes.ftnt2.ftnt21 {
        margin-left: 6px;
        padding-right: 14px;
    }
    .ftnt-sft1 {
        margin-left: 9px;
    }
    .box-image {
        position: relative;
    }
    span.fpo-txt {
        font-size: 80px;
        color: #ec008c;
        font-weight: 600;
        position: absolute;
        top: 38%;
        left: 38%;
        opacity: 0.2;
        transform: rotate(-45deg);
    }
    span.fpo-txt.fpo-txt2 {
        top: 15%;
    }
    span.fpo-txt.fpo-txt1 {
        top: 62%;
    }
    h2.heading.heading-prep {
        margin-top: -2px !important;
    }
    h2.heading.pt-0 {
        margin-top: -20px !important;
        margin-bottom: 15px;
    }
}
/* end min 991px */

@media screen and (min-width: 768px) {
    table.customTable.desktop-only {
        display: table;
    }

    .btc-hcp.efficacy .nccn-category-bar {
        margin-left: 0px;
        width: 97%;
    }

    .btc-hcp.efficacy .ml-20 {
        margin-left: 20px;
        margin-bottom: 40px;
    }

    .btc-hcp.efficacy .box-heading {
        margin-top: -30px;
        padding: 0 10px 0 35px;
    }
    .box-image.box-image-by-desease p.box-heading {
        max-width: 575px;
        padding-bottom: 10px;
    }
    .box-image.box-image-primary-progession p.box-heading {
        width: 470px;
    }
    
    .btc-hcp.efficacy .box-survival {
        margin-top: 22px;
    }

    .box-survival p.box-heading:before {
        left: -23px;
    }

    .btc-hcp.efficacy .box-survival .box-heading {
        padding-left: 60px;
    }

    .list-sec.list-sec-sovrl ul.arrow-list.pr-0 {
        padding-left: 34px;
    }
    .list-sec.list-sec-sovrl.list-sec-sovrl1 ul.arrow-list.pr-0 {
        padding-left: 25px;
    }
    .btc-hcp.efficacy .mt-10 {
        margin-bottom: 10px;
    }

    .btc-hcp.efficacy .progression-free-survival-sec .cssul.arrow-list {
        padding-left: 43px;
    }

    .discon-imfi-blck p:nth-child(6) span.treat-body {
        margin: 29px 25px 29px;
    }

    .with-imfi-blck p:nth-child(7) {
        padding-bottom: 28px;
    }

    .ef-stud-bullet-sec-11 .bullet-list, .ef-stud-bullet-sec-11 p {
        margin-left: 60px;
    }

    .analysis-sec p {
        font-size: 17px;
    }

    .analysis-sec p span.ff-rr {
        text-align: center;
    }

    .sf-treat-modi-table .customTable td {
        padding: 1.5px 7px;
    }

    .sf-treat-modi-table th:nth-child(2) {
        width: 43%;
    }

    .reduction-text.customMargin.customSize {
        font-size: 16px;
    }
    p.reduction-text.customMargin.customSize {
        margin-top: 27px;
    }
}

@media screen and (max-width: 991px) {
    .btc-hcp li.order-res-link.order-res-dropdown-link.visible-xs.visible-sm.active.open-submenu ul li a{
        padding: 11px 0 12px 38px !important;
        font-weight: 400;
    }
    .btc-hcp .rate-box {
        height: 120px;
    }

    .mb-10-m {
        margin-bottom: 10px !important;
    }

    .btc-hcp  p.disclaimer-eyebrow.saf-margin {
        margin: 0 0 -10px;
    }

    .btc-hcp  p.eyebrow.saf-margin {
        margin-bottom: -5px;
    }

    .btc-hcp  h2.saf-margin {
        margin-bottom: 0;
    }

    .btc-hcp  p.footnotes.saf-margin {
        margin-bottom: 40px;
    }

    .btc-hcp  h2.saf-lab-margin {
        margin-bottom: 20px !important;
    }

    .dosing .scroll-header-wrapper,
    .additional-analyses .scroll-header-wrapper,
    .efficacy .scroll-header-wrapper {
        overflow: initial;
        margin-left: 0;
        margin-right: 0;
    }

    .dosing .scroll-header,
    .additional-analyses .scroll-header,
    .efficacy .scroll-header {
        width: max-content;
        background: #ffffff;
    }

    .dosing p.bar {
        width: 260px;
        background: #EDEDED;
    }

    /*Bharathi's changes*/
    .additional-analyses .mobile-swipe-chart-eff-pres-chart1 {
        overflow: scroll;
    }

    .additional-analyses .mobile-swipe-chart-eff-pres-chart1 .scroll-header-wrapper p.bar {
        width: 317px;
    }

    .efficacy .survival-prespecified-chart .scroll-header-wrapper p.bar {
        /* width: 707px; */
        width: 380px;
    }


    .additional-analyses .mobile-swipe-chart-eff-pres-chart-ttd,
    .efficacy .survival-prespecified-chart {
        overflow: scroll;
    }

    .additional-analyses .mobile-swipe-chart-eff-pres-chart-ttd .scroll-header-wrapper {
        margin-bottom: 10px;
    }

    .additional-analyses .mobile-swipe-chart-eff-pres-chart-ttd .scroll-header-wrapper p.bar {
        width: 266px;
    }

    /* .mobile-only.visible-xs.mobile-swipe-chart.survival-prespecified-chart.key-base-line .left-img img {
        max-width: 119.5px;
        margin-top: 0.45em;
    } */

    body.efficacy .combine-img.mobile-only.eff-pres-chart.key-base-line .left-img img {
        max-width: 225.5px;
        margin-top: 5px;
    }

    body.efficacy .combine-img.mobile-only.eff-pres-chart.key-base-line .right-img img {
        max-width: 367px !important;
        width: auto !important;
        margin-left: 101px;
        margin-top: -2px;
    }
    .efficacy .survival-prespecified-chart .scroll-header-wrapper p.bar.bar-keybase {
        width: 310px;
    }
    .combine-img.mobile-only.eff-pres-chart.key-base-line {
        margin-top: 15px;
    }
    .mobile-only.visible-xs.mobile-swipe-chart.survival-prespecified-chart {
        margin-top: 20px !important;
    }

    .safety .mobile-swipe-chart-eff-pres-chart1 {
        overflow: scroll;
    }
    .safety .scroll-header-wrapper {
        overflow: initial;
        margin-left: 0;
        margin-right: 0;
    }
    .safety .scroll-header {
        width: max-content;
        background: #ffffff;
    }
    .safety .mobile-swipe-chart-eff-pres-chart1 .scroll-header-wrapper p.bar.bar-preval {
        width: 456px;
    }
    body.safety .mobile-swipe-chart .eff-pres-chart.eff-pres-chart1 .right-img.right-img-preval {
        margin: 0 0 0 0 !important;
        padding-left: 0;
        width: auto !important;
        overflow: initial;
    }
    body.safety .mobile-swipe-chart .eff-pres-chart.eff-pres-chart1 .right-img img {
        max-width: 693px !important;
        width: 693px !important;
        margin-top: 3px;
        margin: 13px 0 0 0 !important;
    }

    .real-world-evidence .mobile-swipe-chart-eff-pres-chart-ttd {
        overflow: scroll;
    }
    .real-world-evidence .mobile-swipe-chart-eff-pres-chart-ttd .scroll-header-wrapper {
        margin-bottom: 20px;
        overflow: initial;
        margin-left: 0;
        margin-right: 0;
    }
    /* body.real-world-evidence .mobile-swipe-chart .eff-pres-chart.eff-pres-chart-ttd {
        margin-bottom: 10px;
    } */
    .real-world-evidence .box-image.pb-0 {
        padding-bottom: 0 !important;
        padding-right: 3px !important;
    }
    .real-world-evidence .scroll-header {
        width: max-content;
        background: #ffffff;
    }
    .real-world-evidence .mobile-swipe-chart-eff-pres-chart-ttd .scroll-header-wrapper p.bar {
        width: 117px;
    }
    body.real-world-evidence .mobile-swipe-chart .eff-pres-chart.eff-pres-chart-ttd .left-img {
        padding-left: 0;
        max-width: 106px !important;
        width: 106px !important;
        margin-top: 1px;
        position: absolute;
        left: 12px;
    }
    body.real-world-evidence .mobile-swipe-chart .eff-pres-chart.eff-pres-chart-ttd .left-img img {
        max-width: 133px !important;
        width: 133px !important;
        margin-top: 0px !important;;
    }
    body.real-world-evidence .mobile-swipe-chart .eff-pres-chart.eff-pres-chart-ttd .right-img {
        padding-left: 0;
        margin: -25px 0 0 125px !important;
        overflow: initial;
    }
    body.real-world-evidence .mobile-swipe-chart .eff-pres-chart.eff-pres-chart-ttd .right-img img {
        max-width: 254px !important;
        margin: 25.9px 0 0px 5px !important;
    }

    .real-world-evidence .mobile-only.visible-xs.mobile-swipe-chart.mobile-swipe-chart-eff-pres-chart-ttd {
        margin-top: 30px;
    }

    .about-btcs #column-txt-heading {
        font-size: 16px;
        line-height: 20px;
    }

    body.efficacy.btc-hcp .reference-section {
        padding-right: 9px;
    }

    body.efficacy.btc-hcp h2#eff-head-1+.box-image {
        margin-bottom: 40px;
    }

    .btc-hcp .switch-section a:before, .switch-section a:after {
        top: 50%;
        transform: translateY(-50%);
    }

    .btc-hcp .switch-section a.switch-after:before {
        transform: translateY(-50%) rotate(180deg) !important;
    }

    .btc-hcp .switch-section .switch-after {
        text-align: right;
        display: flex;
        align-items: center;
    }

    .about-btcs .switch-section .switch-after {
        padding: 0 40px 0 0px;
    }

    .about-btcs .switch-section .switch-before {
        padding: 0 0 0 40px;
    }

    .rw-evidence ul.arrow-list {
        padding-right: 0;
        margin-bottom: 25px;
    }

    .btc-hcp .switch-section .switch-before {
        display: flex;
        align-items: center;
    }

    .box-survival img.desktop-only.img-box-padding+img {
        padding: 0;
        margin-bottom: 10px;
    }

    body.dosing.btc-hcp p.footnotes.fn-2 {
        margin-top: 5px;
    }
    .txt-indent-4{
        text-indent: -4px !important;
    }
    .pr-4 {
        padding-right: 4px;
    }

    p.box-heading:before, h2.box-heading:before {
        /* top: -3.6px !important; */
        /* top: -3.6px !important; */
    }

    .box-image-sd .mid-content {
        padding: 15px 0;
    }

    .box-image-sd p {
        font-size: 17px;
        line-height: 17px;
        margin-bottom: 8px;
    }

    .box-image-sd .blue-text p {
        font-size: 17px;
        line-height: 17px;
        margin-bottom: 5px;
    }

    .box-image-sd .month-wrapper img.vs {
        width: 18px;
        margin: 0 12px;
    }

    .box-image-sd .blue-text p span.light, .box-image-sd .grey-text p span.light {
        font-size: 12px;
        line-height: 17px;
    }

    .box-image-sd .blue-text p span.bold {
        display: inline-block;
    }

    .box-image-sd p.hr-txt {
        color: #4a4a4a;
        font-size: 15px;
        line-height: 19px;
    }

    .box-image-sd hr {
        margin: 13px auto;
    }

    .recommended-dosage p.footnotes {
        font-size: 12px;
        line-height: 14px !important;
        letter-spacing: 0;
        margin: 0 0 8px !important;
    }

    .recommended-dosage p.footnotes.fn-2 {
        margin: 0 0 3px !important;
    }

    .treatment-modifications-sec .list-sec li {
        padding-right: 4px;
    }

    .box-image.box-image-tbl-dosing {
        margin-top: 20px;
    }

    .box-image.box-image-tbl-dosing p.footnotes {
        letter-spacing: 0.02px;
        font-family: 'Ubuntu', sans-serif;
        font-size: 12px;
        line-height: 14px;
        /* padding-right: 4px; */
    }

    .dosing p.footnotes {
        font-size: 12px;
        line-height: 14px;
        letter-spacing: 0.02px;
        padding-right: 1px;
    }

    .box-image.box-image-tbl-dosing {
        margin: 30px 10px 25px;
    }

    .prescribing-info {
        line-height: 20px;
    }

    h2.heading.heading-prep {
        margin: -10px 0 15px !important;
    }

    .safety p.footnotes {
        letter-spacing: -0.32px;
        font-size: 12px;
        line-height: 14px !important;
    }

    .safety .arrow-list li {
        padding-left: 4px;
        padding-right: 8px;
        letter-spacing: -0.12px;
    }

    .safety .arrow-list li:nth-child(4) {
        padding-right: 0px;
        letter-spacing: -0.22px;
    }

    .ls-normal {
        letter-spacing: normal !important;
    }
    .section-heading p{
        padding-top: 2px !important;
    }
    .dosing .section-heading span {
        padding: 7px 11.4px !important;
    }
    .dosing .section-heading p {
        padding-top: 3px !important;
    }
    body.safety.btc-hcp.btc-popup-1.modal-open.mobile {
        padding-right: 0 !important;
    }
    body.real-world-evidence.btc-hcp.btc-popup-1.modal-open.mobile {
        padding-right: 0 !important;
    }
}

/* end 991px */

@media screen and (max-width: 767px) {

p.footnotes.ftnt3.ftntspecial {
    text-indent: 0;
}

    .efficacy.btc-hcp .reduction-text sup.per-top.per-top-sft {
        font-size: 15px;
    }

    .efficacy.btc-hcp .reduction-text.customMargin {
        /* font-size: 20px;
        width: 90%; */

        font-size: 17px;
        width: 87%;
        line-height: 18px;
    }

    .efficacy.btc-hcp .updated-os-text {
        margin-top: 10px;
    }

    body.efficacy .sd-and-pc .footnotes sup {
        top: -0.3em;
    }

    sup.single-footnote.top-footnote {
        top: -0.5em !important;
    }
    /* UPDATE */
    p.bar {
        background: #ffffff !important;
    }

    .efficacy.btc-hcp p.reduction-text.customSize2 sup.per-top {
        font-size: 15px;
    }

    .efficacy.btc-hcp p.reduction-text.customSize2 span.big-txt {
        font-size: 17px;
        line-height: 18px;
    }
    .efficacy.btc-hcp p.reduction-text.customSize2 span.big-txt.big-txt1 {
        font-size: 16px;
    }
    .efficacy.btc-hcp p.reduction-text.customSize2 span.red-txt {
        font-size: 16px;
    }

    .efficacy.btc-hcp p.reduction-text.customMargin span.red-txt {
        font-size: 15px;
        line-height: 19px;
        margin-top: 8px;
    }
    .box-light-blue-1 p.reductxt {
        margin:0 0 11px;
    }
    .box-light-blue-1 p.reductxt span.text-nowrap {
        color: #AA212B;
    }
    .ds-btc.table-block th, .ds-btc.table-block td {
        white-space: nowrap;
        font-size: 10px;
        line-height: 11px;
        text-align: left;
    }
    .dosing .ds-btc.table-block th, .dosing .ds-btc.table-block td {
        padding: 4px 10px;
    }
    .ds-btc.table-block td:first-child {
        max-width: 150px;
        white-space: normal;
    }
    .dosing .ds-btc.table-block td:first-child {
        max-width: 110px;
        white-space: nowrap;
    }
    td.tb-sticky.padd-10 {
        padding: 10px 10px !important;
    }

    .tb-sticky {
        position: sticky;
        left: 0;
        z-index: 2;
    }

    /*body.efficacy .box-light-blue.box-survival .scroll-header-wrapper .scroll-header{
	width: 273%; 
}*/

    .btc-hcp .eff-pres-chart .left-img {
        height: auto;
        margin: 0px;
        width: 350px;
        margin-top: 2px;
    }

    .btc-hcp .box-image img {
        width: 100%;
        max-width: 100%;
    }

    .btc-hcp .box-image img {
        width: auto;
    }

    .btc-hcp .box-image img.vs-empty {
        width: 11px;
        height: 11px;
        max-width: 11px;
    }

    .box-image.box-image1 img {
        margin: 30px 0 20px;
    }

    .box-footenote {
        font-size: 12px;
        line-height: 14px;
        letter-spacing: -0.02px;
        text-indent: -6px;
    }

    .box-image.box-image1 {
        padding: 20px 10px 5px 10px !important;
        margin: 30px 10px 25px;
    }

    .real-world-evidence .list-sec {
        margin: 12px auto;
    }

    .real-world-evidence.btc-hcp p.footnotes {
        line-height: 14px;
        font-size: 12px;
    }

    .real-world-evidence.btc-hcp .page-content h2 {
        margin-top: 10px;
    }

    .list-sec.box-ullist ul.arrow-list {
        margin: 0;
        padding-right: 0;
        padding-left: 25px;
    }

    .ds-prep-str-ad .callout.callout-red p {
        padding: 12px 7px 12px 32px;
        letter-spacing: 0.01px;
    }

    .btc-hcp .eff-pres-chart .right-img {
        padding-left: 5px;
        margin-top: 4px
    }

    .callout.callout-red:before {
        background-size: 100%;
        left: -22px;
    }

    .btc-hcp .overall-survival-sec .eff-pres-chart .right-img {
        padding-left: 0;
        /*width: 399.3px;*/
        width: 496px;
        overflow-x: scroll;
    }

    .btc-hcp.efficacy .overall-survival-sec .eff-pres-chart .right-img {
        overflow-x: initial;
        width: auto !important;
        /* margin: 4px 0 0 158px !important; */
        margin: 8.7px 0 0 118px !important;
    }
    .eff-pres-chart .left-img::after{
        content: none !important;
    }

    .btc-hcp.efficacy .overall-survival-sec .mobile-swipe-chart .eff-pres-chart .left-img {
        position: absolute;
        left: 14px;
        width: 119px;
    }

    .btc-hcp.efficacy .overall-survival-sec .mobile-swipe-chart .eff-pres-chart .left-img img {
        /* max-width: 160px;
        margin-top: 0.14em; */
        max-width: 125.7px;
        margin-top: 6.4px;
    }



    /*body.additional-analyses .mobile-swipe-chart .eff-pres-chart .left-img {
        padding-left: 0;
        width: 135px;
    }

	body.additional-analyses .mobile-swipe-chart .eff-pres-chart .left-img img {
		max-width: 135px;
    	width: 135px;
	}

	body.additional-analyses .mobile-swipe-chart .eff-pres-chart .right-img {
        padding-left: 0;
        width:496px;
        overflow-x: scroll;
    }

	body.additional-analyses .mobile-swipe-chart .eff-pres-chart .right-img img {
		max-width: 496px !important;
    	width: 496px !important;
    }

	body.additional-analyses .mobile-swipe-chart .eff-pres-chart.eff-pres-chart1 .left-img {
        width: 83px;
    }
    
    body.additional-analyses .mobile-swipe-chart .eff-pres-chart.eff-pres-chart1 .left-img img {
        max-width: 83px;
        width: 83px;
    }*/

    body.additional-analyses .mobile-swipe-chart .eff-pres-chart.eff-pres-chart1 .left-img {
        padding-left: 0;
        margin-top: 1px;
        max-width: 77px !important;
        width: 77px !important;
        position: absolute;
        left: 30px;
    }

    body.additional-analyses .mobile-swipe-chart .eff-pres-chart.eff-pres-chart1 .left-img img {
        max-width: 85.9px !important;
        width: 85.9px !important;
        margin-top: 10px !important;
        margin: 21px 0 32px -11px !important;
    }

    body.additional-analyses .mobile-swipe-chart .eff-pres-chart.eff-pres-chart1 .right-img {
        padding-left: 0;
        width: auto !important;
        margin: 0 0 0 85px !important;
        overflow: initial;
    }

    body.additional-analyses .mobile-swipe-chart .eff-pres-chart.eff-pres-chart1 .right-img img {
        max-width: 511px !important;
        width: 511px !important;
        margin-top: 3px;
        margin: 22.5px 0 0px 0 !important;
    }

    body.additional-analyses .mobile-swipe-chart .eff-pres-chart.eff-pres-chart-ttd .left-img {
        padding-left: 0;
        max-width: 106px !important;
        width: 106px !important;
        margin-top: 1px;
        position: absolute;
        left: 23px;
    }

    body.additional-analyses .mobile-swipe-chart .eff-pres-chart.eff-pres-chart-ttd .left-img img {
        max-width: 114.3px !important;
        width: 114.3px !important;
        margin-top: 0px !important;
    }

    body.additional-analyses .mobile-swipe-chart .eff-pres-chart.eff-pres-chart-ttd {
        margin-bottom: 10px;
    }

    body.additional-analyses .mobile-swipe-chart .eff-pres-chart.eff-pres-chart-ttd .right-img {
        padding-left: 0;
        /*width: auto !important;*/
        /*margin: 0 0 0 179px !important;*/
        margin:-25px 0 0 125px !important;
        overflow: initial;
    }

    .eff-pres-chart .right-img img {
        max-width: 100% !important;
    }

    body.additional-analyses .eff-pres-chart .right-img img {
        max-width: 424px !important;
        margin: 25.9px 0 0px -14px !important;
    }

    .real-world-evidence .mobile-only.visible-xs.mobile-swipe-chart.mobile-swipe-chart-eff-pres-chart1 .left-img {
        padding-left: 0;
        margin-top: 1px;
        max-width: 77px !important;
        width: 77px !important;
        position: absolute;
        left: 51px;
    }
    .real-world-evidence .mobile-swipe-chart .eff-pres-chart.eff-pres-chart1 .left-img img {
        max-width: 86px !important;
        width: 90px !important;
        margin-top: 10px !important;
        margin: 21px 0 32px -13px !important;
    }
        
    body.additional-analyses .mobile-swipe-chart .eff-pres-chart.eff-pres-chart1 .right-img.right-img-preval {
        margin: 0 0 10px 0 !important;
    }
    .additional-analyses .mobile-swipe-chart-eff-pres-chart1 .scroll-header-wrapper p.bar.bar-preval {
        width: 267px;
    }
    

    body.efficacy .eff-pres-chart .right-img img {
        /*max-width: 732.5px !important;
        width: 732.5px;*/
        /*max-width: 693px !important;
        width: 696px !important;
        margin-left: 2px;*/
        /* max-width: 822px !important;
        width: auto !important;
        margin-left: 2px; */
        max-width: 533px !important;
        width: auto !important;
        margin-left: 7px;
    }

    .btc-hcp p.box-heading {
        /* font-size: 12px;
        line-height: 17px; */
        font-size: 14px;
        line-height: 16px;
    }
    .btc-hcp .box-heading.bh-mob1{
        width: 296px;
        letter-spacing: -0.2px;
    }
    .btc-hcp p.box-heading {
        padding: 0px 10px 0 15px;
        width: 275px;
    }
    .box-image.box-image-sd .box-heading.bh-os {
        width: auto;
        padding-left: 15px;
    }
    .box-light-blue-1 p.box-heading.box-light-blue{
        padding: 6px 10px 6px 15px;
        width: 308px;
        clip-path: polygon(0 0, 100% 0, 100% 0%, 92.5% 100%, 0 100%, 0% 0%);
        -webkit-clip-path: polygon(0 0, 100% 0, 100% 0%, 92.5% 100%, 0 100%, 0% 0%);
        top: -14px;
        left: -16px;
    }
    .about-btcs.btc-hcp p.box-heading {
        width: fit-content;
    }

    .btc-hcp p.eyebrow {
        font-size: 16px;
        line-height: 18px;
    }

    .btc-hcp p.footnotes {
        line-height: 17px;
    }

    .about-btcs p.footnotes {
        font-size: 12px;
        line-height: 14px;
    }

    .btc-hcp .page-content h2 {
        font-size: 22px;
        line-height: 24px;
        letter-spacing: -0.44px;
        margin-top: 14px;
    }
    h2.sub-head-topaz.sub-head-topaz-txt1.subhead-txt1 {
        letter-spacing: -0.50px;
    }
    h2.sub-head-topaz.sub-head-topaz-txt1.subhead-txt1 span.text-nowrap {
        white-space: normal;
    }
    .sub-head-topaz.pr-4 {
        padding-right: 4px !important;
    }
    .ftnt-sft1 {
        margin-bottom: 20px;
    }
    .ftnt-sft1 p.footnotes {
        letter-spacing: -0.4px;
    }
    
    .btc-hcp .data-compare {
        width: 100%;
    }
    .box-image.box-light-blue.box-light-blue-1 .data-compare {
        width: 86%;
    }
    .btc-hcp .data-red-txt, .data-red-txt p {
        font-size: 15px;
        line-height: 17px;
    }
    .box-image.box-light-blue {
        margin: 44px 10px 30px 10px;
    }

    .btc-hcp .data-comp-bottom.data-grey-txt {
        font-size: 15px;
    }

    .btc-hcp .reduction-text {
        font-size: 16px;
        line-height: 18px;
        margin: 0 auto;
        width: 100%;
    }
    p.reductxt {
        font-size: 15px;
        line-height: 19px;
        letter-spacing: -0.45px;
        font-weight: 500;
        margin-top: 8px;
    }
    .btc-hcp.efficacy .text-enlarge{
        font-size: 17px;
        line-height: 17px;
        letter-spacing: -0.51px;
    }
    
    .big-txt br.mobile-only {
        display: block;
    }
    .red-txt {
        font-size: 15px;
        line-height: 22px;
        display: block;
    }

    .progression-free-survival-sec .red-txt {
        display: inline;
        color: #003262;
        letter-spacing: -0.45px;
        line-height: 17px;
    }

    .gray-txt {
        font-size: 15px;
        line-height: 22px;
    }

    .txt-hr-light {
        font-size: 12px;

    }

    .about-btcs.btc-hcp ul.light-txt {
        padding-left: 67px;
        margin-bottom: -10px;
    }

    #txt-heading {
        padding-left: 25px;
    }

    /* b#column-txt-heading {
   position: relative;
   left: -8%;
  } */



    .efficacy.btc-hcp .nccn-category-bar {
        display: flex;
        border-top: 1px solid #707070;
        border-bottom: 1px solid #707070;
        background-color: #7099D326;
        position: relative;
        height: auto;
        margin-left: auto;
        margin-right: auto;
        margin-bottom: 80px;
        margin-top: -50px;
        align-items: center;
        left: 0;
        right: 0;
        padding-left: 0;
        padding-top: 10px;
        padding-bottom: 20px;
    }


    .efficacy.btc-hcp .nccn-expanded-text {
        padding-top: 15px;
        margin-left: -2px;
        padding-right: 4px;
    }

    .efficacy.btc-hcp .nccn-expanded-text p {
        margin-bottom: 0px;
        font-family: 'Ubuntu', sans-serif;
        color: #003262;
        font-size: 14px;
        line-height: 16px;
        margin-left: 13px;
        font-weight: 400;
    }

    .efficacy.btc-hcp .nccn-category-text {
        font-size: 17px;
        color: #003262;
        font-family: 'Ubuntu', sans-serif;
        line-height: 13px;
    }

    .efficacy.btc-hcp .category-text {
        font-size: 13px;
        font-weight: 700;
        font-family: 'Ubuntu', sans-serif;
        width: 83px;
        display: inline-block;
    }

    .efficacy.btc-hcp .nccn-category-text::after {
        margin-left: 10px;
    }

    .efficacy.btc-hcp .nccn-category-text::after {
        content: " ";
        border-right: 1px solid #00294E;
        position: absolute;
        top: 5%;
        bottom: 5%;
        height: 90%;
    }

    .btc-hcp .page-heading {
        margin: 0 15px;
    }

    .btc-hcp .ef-anchor-sec {
        margin: 0 0 20px 15px;
        max-width: 342px;
        display: flex;
        flex-direction: row;
    }

    img.mobile-only.pinch-zoom-txt {
        max-width: 120px;
        margin: 0 auto;
        padding-top: 20px;
        padding-bottom: 15px;
        max-width: 120px !important;
        margin-right: auto !important;
        margin-left: auto !important;
    }

    .sub-head-topaz {
        font-size: 18px !important;
        margin-top: 20px !important;
    }



    .psa-sec {
        display: inline-flex;
        /* align-items: center; */
        align-items: flex-start;
        width: 100%;
        margin-bottom: 25px;
        /* flex-direction: column; */
        margin-left: 10px;
    }

    .psa-sec.top-algn-sec img {
        margin-top: 0;
    }

    .ds-prep-str-ad ul.arrow-list {
        margin-top: 20px;
    }

    .psa-sec img {
        width: 69px !important;
        margin-right: 6px;
        max-width: 67px;
    }

    .ds-prep-str-ad ul.arrow-list {
        margin-top: 30px;
        align-self: flex-start;
        margin-left: -15px;
        padding-left: 40px;
    }
    ul.arrow-list.pr-0.arrow-list-rwe {
        margin-left: 10px;
    }
    .ds-prep-str-ad.ds-prep-str-ad-1 ul.arrow-list {
        padding-left: 0;
        padding-right: 43px;
        margin-left: 0px;
        margin-top: 0;
        align-self: center;
        padding-left: 7px !important;
    }

    .ds-prep-str-ad h1.heading {
        font-size: 24px;
        font-family: 'ubuntu';
        color: #AC182E;

    }

    #eyebrow-dosing {
        font-size: 16px !important;
        margin-top: 0px;
    }

    #subhead-dosing {
        font-size: 18px !important;
        margin-top: -20px;
        letter-spacing: normal;
    }

    .dosing.btc-hcp .callout p {
        padding: 10px 35px;
    }

    h2#dosing-subhead-2 {
        font-size: 18px;
        margin: 0 0 12px;
        padding: 0;
    }

    .dosing.btc-hcp  ul#no-icon-margin {
        padding-right: 0;
        padding-left: 25px !important;
    }

    ul#no-icon-margin {
        margin-left: 0;
        padding-left: 3px;
    }

    .psa-sec.psa-sec-1 li {
        padding-right: 44px;
    }

    .psa-sec.psa-sec-1 {
        margin-bottom: 20px;
    }

    .mb-0 {
        margin-bottom: 0 !important;
    }

    .pt-0 {
        padding-top: 0 !important;
    }

    .heading.heading-dosag {
        margin: 0px 0 25px !important;
        padding: 0;
    }

    .two-columns-txt-btc {
        flex-direction: column;
    }

    b#column-txt-heading {
        font-size: 14px;
    }

    .btc-hcp .page-heading {
        margin: 0 15px;
        padding: 15px 0 15px;
    }
    
    h2.heading.heading-storage {
        margin: 0px 0 10px !important;
        padding-bottom: 0;
        color: #003262;
    }
    h2.sub-head-topaz {
        padding: 0 !important;
        margin: 0;
        font-size: 18px;
        line-height: 22px !important;
    }

    .btc-hcp .callout p {
        padding: 10px 34px;
    }

    #txt-nowrap-2 {
        white-space: wrap;
    }


    .btc-hcp p.eyebrow {
        margin-bottom: -15px;
    }

    #eff-head-1 {
        letter-spacing: -0.55px !important;
    }


    span.big-txt {
        font-size: 16px;
        line-height: 18px;
        letter-spacing: -0.48px;
        color: #003262;
    }

    .percentage-number {
        /* font-size: 36px;
        font-weight: 900; */
    }
    div#dosing-box-1 {
        padding-bottom: 0px !important;
        padding-right: 0px !important;
        padding-left: 0 !important;
    }
    #dosing-box:before {
        top: -3.5px;
        left: -19px;
    }

    p.disclaimer-eyebrow {
        letter-spacing: -0.27px;
        line-height: 20px;
    }
    div#dosing-box-1 img.mobile-only {
        margin-left: 6px;
    }
    h1#dsg-sp1 {
        margin-top: -.5rem;
    }

    #subhead-safety {
        margin-top: .5rem !important;
    }

    /* END */


    .btc-table-section {
        margin: 0 auto;
        max-width: 355px;
    }

    .chart-img img.mobile-only, .chart-img {
        margin: 0 auto;
    }

    .ef-orr-Chart.chart-img img {
        display: block;
    }

    .btc-hcp main#maincontent {
        margin-top: 94px;
    }

    .subpage-banner {
        height: 90px;
    }

    /* .page-content {
       padding: 0 10px 0 10px;
       overflow: hidden;
   } */
    .sec-header-container {
        padding-top: 4px;
    }

    p.nccn-txt {
        margin-top: 5px;
        font-size: 28px;
    }

    .banner-liv-img {
        margin: 0 15px 0 -55px;
    }

    .subpage-banner .banner-subhead-block hr {
        width: 25px;
    }

    .banner-liv-img img {
        max-width: 63px;
    }

    p.banner-heading {
        font-size: 42px;
    }

    .subpage-banner p.banner-subhead {
        font-size: 10px;
        max-width: 143px;
    }

    .ef-dor-Chart {
        margin-bottom: 10px;
    }

    .analysis-sec p span.sot-reg {
        display: block;
    }

    .hr-footnote p, .os-pfs-head p {
        font-size: 17px;
    }

    .red-lined hr {
        width: 10%;
    }

    .sf-treat-modi-table .red-lined hr {
        width: 5%;
    }

    .overall-survival-sec .os-pfs-head hr {
        width: 10%;
    }

    .ef-OS-Forrest-Plot-Chart hr {
        width: 41%;
    }

    table.customTable {
        margin-top: 10px;
        letter-spacing: -0.5px;
    }

    .customTable th, .customTable td {
        padding: 4px 4px;
    }

    .sec-header {
        padding: 5px 11.5px 5px 11.5px;
    }

    .overall-survival-sec .eyebrow-txt {
        margin-top: 25px;
    }

    .overall-survival-sec .analysis-sec, .progression-free-survival-sec .analysis-sec {
        margin-top: 10px;
        padding-top: 10px;
    }

    .ef-orr-Chart img {
        margin: 17px auto 50px;
    }

    .analysis-sec {
        flex-direction: column;
    }

    .analysis-sec p {
        font-size: 17px;
        line-height: 20px;
        text-align: center;
    }

    .analysis-sec img.mobile-only {
        margin: 0 auto;
        display: block;
    }

    .main-txt {
        font-size: 18px;
        line-height: 21px;
        margin: 10px auto;
    }

    .ef-mtr-Chart .footnotes {
        margin: 30px auto 33px;
    }

    .ef-dor-Chart hr {
        width: 38%;
    }

    .callout-sec p {
        letter-spacing: -0.3px;
        margin-right: 0;
    }

    span.nccn-subtxt {
        font-size: 8px;
        letter-spacing: 0.06px;
        line-height: 12px;
        margin-top: 0;
    }

    .ef-orr-dor .sec-header-container {
        margin-bottom: 34px;
    }

    .ef-orr-mtr-img-sec {
        flex-direction: column;
        width: 100%;
    }

    .ef-orr-mtr-img-sec div {
        width: 100%;
    }

    .ef-orr-Chart {
        margin-right: 0px;
    }

    .ef-bullet-img-blck, .ef-bullet-bullet-blck {
        flex-direction: column;
    }

    .ef-stud-eligibility-section p.bullet-heading {
        text-align: center;
    }

    .ef-bullet-img-blck {
        padding-bottom: 15px;
    }

    .ef-stud-eligibility-section {
        padding-bottom: 5px;
    }

    .ef-stud-bullet-sec-4 {
        padding-bottom: 15px;
    }

    .ef-stud-bullet-sec-1, .ef-stud-bullet-sec-2 {
        width: 100%;
    }

    .ef-stud-bullet-sec-2 {
        border-bottom: 1px solid #74A9D9;
        margin-bottom: 30px;
    }

    .ef-mtr-Chart .table-heading {
        margin: 20px 0;
    }

    .sf-ar-table td.span4, .sf-lab-abnormalities-table td.span4 {
        background-color: #E6EAF1;
        font-size: 15px;
        line-height: 16px;
        text-align: center;
    }

    .sf-ar-table .customTable td:nth-child(1) {
        text-align: center;
    }

    .sf-lab-abnormalities-table .mobile-only.customTable th, .sf-lab-abnormalities-table .mobile-only.customTable td {
        width: 10%;
        text-align: center;
    }

    .ef-key-patient-char-table .customTable td:nth-child(1) {
        text-align: center;
    }

    .rd-compare-sec {
        flex-direction: column;
        align-items: center;
    }

    .OS-KM-Curve-Chart {
        margin: 15px auto 33px;
    }

    .overall-survival-sec .callout-sec {
        margin: 26px auto;
    }

    h1.heading.os-result {
        margin: 35px auto 26px;
    }

    .psa-sec img {
        width: 49px;
    }

    .sf-treat-modification-section {
        flex-direction: column;
    }

    .sf-treat-modification-section div {
        width: 100%;
        margin: 0;
    }

    .ef-key-patient-char-table .table-heading hr {
        width: 13%;
    }

    /*.comp-sepline-sec {
       transform: rotate(90deg);
       max-height: 25px;
       margin-left: 180px;
   }*/
    .rd-start-with, .rd-continue {
        width: 100%;
        max-width: 355px;
    }

    p.rd-compare-head {
        font-size: 20px;
        line-height: 22px;
    }

    .treatment-modifications-sec p.sec-header-container {
        margin: 50px auto 25px;
    }

    .dis-rate-section {
        padding: 10px 25px 0px;
    }

    .sf-lab-abnormalities-table .customTable {
        margin-bottom: 35px;
    }

    .sf-lab-abnormalities-table .table-heading hr {
        width: 33%;
    }

    .dis-rate-comp p {
        line-height: 25px;
    }

    .sf-ebook-blck p {
        max-width: 306px;
        margin: 0 auto 20px;
    }

    td.chart-body {
        font-size: 15px;
        color: #173A64;
        font-family: 'RobotoCondensed-Bold';
    }

    .customTable.mobile-only th:first-child {
        border-left: 0;
    }

    th.bg-white-cell {
        border-top: 0.5px solid #7099D3;
    }

    .with-imfi-blck hr {
        width: 25%;
    }

    .discon-imfi-blck .red-lined.table-heading.treat-head hr {
        width: 10%;
    }

    p.treat-last {
        margin-bottom: 30px;
    }

    .sf-treat-modification-section .table-heading {
        margin-bottom: 20px;
    }

    .rd-compare-sec hr {
        width: 30%;
    }

    .comp-sepline-sec img {
        margin: 25px auto;
    }

    .red-lined hr {
        height: 1px;
    }

    .dis-rate-comp p span.sot-reg {
        display: block;
        margin-top: 5px;
    }

    .progression-free-survival-sec .os-pfs-head.in-w hr {
        width: 16%;
    }

    /***scroll-table-styling***/
    .scroll-header-wrapper {
        overflow-x: auto;
    }

    .scroll-header {
        display: flex;
        background: #EDEDED;
        align-items: center;
        justify-content: space-between;
        border: 0.5px solid #9F9F9F;
        width: 181%;
    }

    .btc-hcp .scroll-header p {
        /* font-family: Roboto-bold, sans-serif;
       padding: 6px 0px;
       margin: 0;
       font-size: 12px;
       margin-right: 8px;
       margin-left: 8px;
       margin-top: 1px; */
        /* font-family: Roboto-bold, sans-serif; */
        font-family: Roboto, sans-serif;
        padding: 4px 20.2px;
        margin: 0;
        font-size: 12px;
        /* margin-right: 8px; */
        /* margin-left: 8px; */
        /* margin-top: 1px; */
        background: #a5a9a5;
        color: #fff;
    }

    .scroll-header i {
        border: solid #555555;
        border-width: 0 2px 2px 0;
        display: inline-block;
        padding: 2px;
        top: -1px;
        position: relative;
    }

    i.arrow.left, i.arrow.right {
        margin-right: 5px;
    }

    i.arrow.right {
        margin-left: 5px;
    }

    .right {
        transform: rotate(-45deg);
        -webkit-transform: rotate(-45deg);
    }

    .left {
        transform: rotate(135deg);
        -webkit-transform: rotate(135deg);
    }

    p.bar {
        width: 55px;
        height: 11px;
        background: #BEBEBE;
    }

    .combine-img {
        display: flex;
    }

    .mobile-swipe-chart .left-img {
        margin-top: 57px;
    }

    .mobile-swipe-chart .left-img img {
        max-width: 156px;
        margin-top: -1px;
    }

    .mobile-swipe-chart .right-img {
        overflow-x: auto;
    }

    .right-img::-webkit-scrollbar {
        display: none;
    }

    .sf-treat-modi-table .bb-fff {
        border-bottom: 0.5px solid #ffffff;
    }

    .sf-treat-modi-table td.chart-body {
        font-family: 'HelveticaNeueLTStd-LtCn';
        color: #2B2E34;
    }

    .switch-section a.two-line {
        padding: 20px 50px 30px 0px;
        text-align: right;
    }

    hr.os-data-hr {
        width: 8%;
    }

    .progression-free-survival-sec .table-heading hr {
        width: 18%;
    }

    .rate-box-block {
        flex-direction: column;
    }

    p.box-heading.box-heading-12 {
        font-size: 12px;
        line-height: 15px;
        width: 299px;
        padding: 0px 10px 0 11px;
    }

    .rate-box img {
        margin: 0 -13px !important;
        padding: 0;
    }

    .rate-box p {
        left: 0;
    }

    .discontinuation-rates-sec .box-image {
        margin: 10px 10px 30px !important;
    }

    .immune-mediated .page-content h2 {
        margin: 20px auto 15px;
        padding: 0;
    }

    .safety .box-image {
        margin: 30px 10px !important;
    }

    .immune-mediated .list-sec {
        margin-top: 15px;
    }

    h2#\#subhead-safety {
        padding-right: 9px !important;
    }

    .immune-mediated p.box-heading {
        font-size: 12px;
        line-height: 14px;
        width: 260px;
    }

    .immune-mediated .box-image {
        padding: 20px 2px 0px 12px !important;
    }

    .mt50 {
        margin-top: 30px !important;
    }

    .immune-mediated p.footnotes.ftnt1 {
        padding-right: 20px;
        margin-bottom: 20px;
    }

    .safety .immune-mediated .arrow-list li {
        padding-right: 8px;
        margin-bottom: 9px;
    }

    .safety .immune-mediated .callout.dosing-box1-callout.callout-red p {
        padding: 10px 24px 10px 34px;
    }
    .list-sec.list-sec-3yr ul.arrow-list {
        padding-left: 24px;
    }
    .list-sec.list-sec-3yr ul.arrow-list li {
        padding-right: 28px;
    }
    p.footnotes.ftnt3{
        padding-right: 14px;
        margin-left: 5px;
    }
    .efficacy .box-heading.bh-pri-ana{
        width: 286px;
    }
    p.footnotes.ft1-mob {
        /* letter-spacing: -0.6px; */
        margin: 30px auto 30px;
    }
    .pr-4{
        padding-right: 4px !important;
    }
    .box-image.box-survival.mb-20 p.box-heading {
        width: 222px;
    }
    .box-image.box-image-primary-progession p.box-heading {
        width: 276px;
        padding: 0px 10px 0 26px;
    }
    .box-image.box-image-by-desease p.box-heading {
        /* width: 185px; */
        width: 262px;
    }
    p.box-heading.bh-confirm-obj {
        width: 265px;
    }
    p.footnotes.ftnt4 {
        padding-right: 3px;
        margin-bottom: 20px;
    }
    .ls-3{
        letter-spacing: -0.3px !important;
    }
    .color-blue{
        color: #003262;
    }
    .mr-mob{
        margin:7px auto 9px;
        display: inline-block;
    }
    p.footnotes.ftnt5 {
        letter-spacing: -0.8px;
        margin-bottom: 50px;
    }
    p.footnotes.ftnt6 {
        font-size: 12px;
        line-height: 14px;
        letter-spacing: 0.02px;
    }
    p.footnotes.ftnt6 {
        font-size: 12px;
        line-height: 14px;
        letter-spacing: 0.02px;
        margin-bottom: 40px;
        margin-top: 0;
    }
	.box-image-primary-progession p.footnotes.ftnt6 {
        padding: 20px 15px 0 15px;
    }
    .pr-22{
        padding-right: 22px !important;
    }
    p.footnotes.ftnt7 {
        font-size: 12px;
        line-height: 14px;
        letter-spacing: 0.02px;
        margin-bottom: 40px;
        margin-top: 0;
        margin-left: 5px;
        text-indent: -4px;
    }
    .bh-med{
        width: 220px !important;
    }
    p.footnotes.ftnt8 {
        font-size: 12px;
        line-height: 14px;
        letter-spacing: 0.02px;
        margin-bottom: 30px;
        margin-top: 0;
        margin-left: -3px;
    }
    .list-sec.list-sec-sovrl li.pr-4 {
        padding-right: 18px !important;
    }
    .mt--10{
        margin-top: -10px !important;
    }
    .box-image.box-image-topaz p.box-heading {
        width: 205px;
    }
    .ftnt-topaz {
        padding: 0 6px;
        margin-bottom: 25px;
        margin-left: 4px;
    }
    .ftnt-topaz p.footnotes {
        letter-spacing: -0.1px;
        font-size: 12px;
        line-height: 14px !important;
    }
    /*.ftnt-topaz p.footnotes:first-child {
        margin-bottom: 23px;
        font-size: 14px;
        line-height: 16px;
        letter-spacing: 0.03px;
    }*/
    p.footnotes.ftnt8.mb-15 {
        margin-bottom: 10px;
    }
    .footnote-key-base {
        margin-top: 7px;
    }
    .footnote-key-base p.footnotes {
        font-size: 12px;
        line-height: 14px;
        margin-left: -7px;
    }
    .list-sec.list-sec-sovrl {
        margin-bottom: 15px;
    }
    p.footnotes.ml-20 {
        /* margin-bottom: 35px; */
    }
    p.box-heading.bh-surv-viral {
        width: 208px !important;
    }
    .switch-section .switch-before {
        padding: 30px 0 30px 40px !important;
    }
    .switch-section .switch-after {
        padding: 30px 40px 30px 0px !important;
    }
    .list-sec.list-sec-sovrl.mt-0 {
        margin-top: 0;
    }
    td:first-child:after, th:first-child:after{
        background: #707070 !important;
        box-shadow: none !important
    }
    .combine-img.mobile-only.eff-pres-chart.table1-dose {
        margin-top: 20px;
    }
    .table1-dose .extended-text {
        width: 210%;
    }
    .box-image.box-image-disconti {
        margin: 8px 10px !important;
    }
    .box-image.box-image-disconti p.box-heading {
        font-size: 12px;
        line-height: 15px;
        width: 291px;
        padding: 0px 10px 0 12px;
        letter-spacing: -0.3px;
    }
    .ef-immune-mediated-ar.immune-mediated h2#\#subhead-safety {
        margin-bottom: 0 !important;
        padding: 0 !important;
        letter-spacing: 0;
    }
    p.footnotes.ls-normal span.ast-footnote {
        margin-left: -4px;
    }
    .immune-mediated p.footnotes.ls-normal {
        margin-bottom: 40px;
    }
    .box-image.box-image-ovrall-freq img.mobile-only {
        margin: 0 -11px;
        max-width: 103%;
    }
    .safety .immune-mediated ul.arrow-list.arrow-list-1 li {
        padding-right: 14px;
    }
    .ef-immune-mediated-ar.immune-mediated .sf-lab-ab h2 {
        letter-spacing: 0;
    }
    .safety .immune-mediated ul.arrow-list.pr-0 li {
        padding-right: 10px;
    }
    img.explor-tbl-bottom-img {
        position: relative;
        bottom: 24px;
        margin: 0 auto !important;
        width: 200px !important;
    }
    p.footnotes.ftnt-dease {
        margin: 0px 3px -30px;
    }
    p.footnotes.ftnt-dease.ftnote-ds {
        margin: -5px 0 15px;
    }
    .arrow-list li:before{
        left: -28px !important;
    }
    ul.arrow-list {
        padding-left: 28px !important;;
    }
    .btc-hcp .ft-font12{
        font-size: 12px;
        line-height: 14px !important;
        letter-spacing: 0.02px;
    }
    .box-image.box-image-bi-med img.mobile-only {
        margin-top: -4px;
    }
    .box-image.box-image-bi-med {
        margin-bottom: 0 !important;
    }
    .box-image.box-image-per-ongo.box-image-per-ongo1 {
        margin-top: -5px;
    }
    .btc-hcp p.box-heading {
        margin-top: -29px;
    }
    .box-image.key-table p.box-heading {
        width: 160px;
    }
    .box-image.box-image1.box-image-space p#box-heading-1 {
        max-width: 160px;
    }
    .box-image.box-image-by-desease {
        margin-top: 17px;
    }
    .box-image.viral-hep {
        margin-top: 20px;
    }
    p.footnotes.ftnt-time {
        margin-left: -5px;
        color: #4a4a4a;
        letter-spacing: -0.1px;
        text-align: left;
    }
    .box-image.box-image-sd p#box-heading-1::before {
        top: -4px;
    }   
    .font15 {
        font-size: 15px !important;
        line-height: 19px !important;
        letter-spacing: -0.45px !important;
        margin-bottom: 5px !important;
    }
    .month-wrapper.month-wrapper-sd .grey-text .bold {
        font-size: 17px;
        line-height: 17px;
    }
    .box-image.box-image1 p#box-heading-1::before {
        left: -31px;
        top: -3px;
    }
    .mt-22{
        margin-top: 22px !important;
    }
    .box-heading.bh-paitchar {
        max-width: 238px !important;
    }
    .box-heading.bh-over-surv {
        max-width: 230px;
    }
    .box-heading.bh-prog-free {
        max-width: 227px;
        padding: 0px 0px 0 15px !important;
    }
    .sub-head-topaz.pr-4.pr-11 {
        padding-right: 11px !important;
    }
    .box-image.box-image-topaz {
        padding: 20px 5px 10px 10px !important;
    }
    .box-image.box-image-topaz p.box-heading:before {
        left: -32px;
    }
    .box-image.box-image-primary-progession {
        padding: 20px 5px 10px 5px !important;
        margin-top: 22px;
    }
    .box-image.box-image-primary-progession p.box-heading::before {
        left: -27px;
    }
    .box-image.box-image-primary-progession p.footnotes.ftnt5 {
        margin-left: 11px;
    }
    .data-compare.data-compare-pri-progre {
        width: 72%;
        margin-top: 5px;
        margin-bottom: 15px;
    }
    .data-compare.data-compare-pri-progre p.data-num {
        line-height: 17px;
    }
    .data-compare.data-compare-pri-progre .data-comp-vs {
        padding: 0;
    }
    .eyebrow.mt-25{
        margin-top: 18px;
    }
    .data-compare.data-compare20per {
        margin: 13px auto 20px;
    }
    .data-compare.data-compare20per .data-comp-bottom.data-grey-txt p.data-num {
        line-height: 17px;
    }
    .data-comp-bottom.data-grey-txt p.data-num {
        line-height: 17px;
    }
    .box-image.viral-hep img {
        margin-top: 15px;
    }
    p.footnotes.ml-20.ft-font12 {
        margin-top: 33px;
        margin-bottom: 28px;
    }
    .efficacy .section-heading span {
        padding: 8px 12.1px;
        position: relative;
        top: 2px;
    }
    p.box-heading strong {
        font-size: 18px;
        font-family: 'RobotoCondensed-Bold';
    }
    h2.mt-12 {
        margin-top: 12px !important;
    }
    strong.gt-symbol {
        font-size: 23px;
        font-family: Roboto-bold, sans-serif;
    }
    span.gt-symbol {
        font-family: inherit;
    }
    .box-image.box-survival.mb-20 {
        margin-top: 20px;
    }
    .box-image.box-survival.mb-20 img.mobile-only {
        margin: 15px -7px 0;
        max-width: 104%;
    }
    .list-sec.list-sec-sovrl ul.arrow-list.pr-0 {
        padding-left: 20px !important;
        padding-right: 10px !important;
    }
    .box-image.box-survival.mb-20 p.footnotes.ftnt4 {
        padding-right: 13px;
        margin-bottom: 20px;
        margin-left: 0;
    }
    h2.pr-30 {
        padding-right: 15px !important;
    }
    .box-image.box-image-ovrall-freq span.gt-symbol {
        font-size: 14px;
    }
    span.gt-symbol.font14 {
        font-size: 14px !important;
    }
    .box-image {
        position: relative;
    }
    span.fpo-txt {
        font-size: 50px;
        color: #ec008c;
        font-weight: 600;
        position: absolute;
        top: 35%;
        left: 30%;
        opacity: 0.2;
        transform: rotate(-45deg);
        pointer-events: none;
    }
    span.fpo-txt.fpo-txt2 {
        top: 15%;
        font-size: 50px;
        pointer-events: none;
    }
    ul.arrow-list.arrow-list-eff2 {
        padding-left: 48px !important;
    }
    img.mobile-only.mob-img-marg {
        margin-bottom: 12px;
    }
    span.fpo-txt.fpo-txt1 {
        font-size: 50px;
        top: 58%;
        pointer-events: none;
    }
}

/* end 767px */
@media screen and (max-width: 320px) {
    table.customTable {
        letter-spacing: -0.8px;
    }

    .customTable th, .customTable td {
        padding: 4px 1px;
    }

    .tag-purple-color {
        border: 0.7px solid #5b305d;
        border-top: none;
    }

    .ef-OS-Forrest-Plot-Chart .efficacy-page .right-img img {
        max-width: 653px;
    }

    .ef-orr-dor .sec-header {
        max-width: 198px;
    }

    .table-heading p, .rd-compare-sec .table-heading p {
        font-size: 15px;
    }

    .dis-rate-comp p.red-txt {
        padding-right: 30px;
    }

    .dis-rate-comp p {
        padding-left: 30px;
    }
}

@media screen and (max-width: 328px) {
    .dis-rate-comp p.red-txt {
        padding-right: 30px;
    }

    .dis-rate-comp p {
        padding-left: 30px;
    }

    .switch-section a.two-line {
        padding: 20px 50px 30px 0px;
    }

    p.rd-comp-footnote.rd-comp-foot-1 {
        margin-left: 35px;
    }

    .ef-orr-dor .sec-header-container {
        display: flex;
        padding: 0;
    }

    .banner-liv-img {
        margin: 0 10px 0 -30px;
    }
}

@media screen and (-ms-high-contrast: active), (-ms-high-contrast: none) {
    .banner-liv-img {
        top: 0;
    }

    .analysis-sec hr {
        right: 20px;
        left: 20px;
        margin: 0;
    }
}

@media screen and (max-width: 355px) {
    .chart-img img, .ef-stud-bullet-sec-11 img.mobile-only {
        max-width: 300px;
    }

    .chart-img .efficacy-page img {
        max-width: fit-content;
    }

    .switch-section a {
        padding: 30px 39px;
    }
}


/********85087*************/

.font-reg{
	font-weight: 400!important;
    }

@media screen and (max-width: 767px) {

	div#dosing-box-1{
		border: none;
    }
        #dosing-box1:before {
       display: none;
    }
    div#dosing-box-1 img.mobile-only{
		margin: -12px 0 0 -3px;
        transform: translateY(-6px) scale(1.09);
    }

    .additional-analyses .os-mutation-status-sec .mobile-swipe-chart-eff-pres-chart1 {
        margin-bottom: 20px;
    }

}


/********85087*************/