/*********************************US-52438********************************************************/
.efficacy .table-blocks .block.last .pt-2{
	font-size: 14px;	
}
.subpage-banner .content-title{
	display: flex !important;
    align-items: center;
    justify-content: center;
}
.callout-content.nccn-new .NCCN-content .right-div p, .studydesign-sec .callout-content .first-sec p{
    font-family: 'Roboto-Medium', sans-serif;
}
span.sec-header{
    background-repeat: no-repeat;
    color: #FFFFFF;
    font-family: 'RobotoCondensed-Bold', sans-serif;
    background-color: #003865;
    padding: 5px 9px;
    border-bottom-left-radius: 8px;
    border-bottom-right-radius: 8px;
}
h1.page-sub-title{
    font-family:'RobotoCondensed-Bold' !important;
    text-align:left;
    color:#AC182E;
    letter-spacing:normal;
}
.sec-header-container{
	margin-top: 2.7em;
}
.sec-header-container.no-barline{
	margin-top: 0;
}
.progressionfree-sec .sec-header-container{
	margin-bottom: 24px;
}
span.astric-sup{
	font-size: 75%;
    top: -3.5px;
    position: relative;
    vertical-align: baseline;
}
.hero-content p.footnote sup{
	top: -2.5px;
    font-size: 7.5px;
}
.efficacy .Standard-care-sec .sec-header-container sup.move-up{
    top: -0.3em;
}
.callout-content.no-leftbar{
	border-left: 1px solid #7099D3;
}
.imfinzicrt .immune-response-sec .newcallout-design p sup{
	top: -0.9em;
}
.dosing .preList li.Injection, .dosing .preList li.Injection p{
	margin-bottom: 0;
}
/*********************************US-52438 End********************************************************/
/*table*/ 
p.dosing_table  img{
	width: 100%;
}
.baseline-disease-table .chart-header:before, .baseline-disease-table .chart-header:after {
    width: 36% !important; 
}
.baseline-disease-table .chart-header {
    width: 58% !important;
}

.safety .first-sec .firstlink p.fact {
    text-align: center;
	color: #ac162c;
}
.safety .first-sec .firstlink p:last-child {
    text-align: center;
    color: #ac162c;
}
.safety .first-sec.right-callout .fact_text{
    margin-left: -3px;
}
.baseline-disease-table p.tablehead-header {
    border: none;
}
.baseline-disease-table .tablehead-cell1 p,.baseline-disease-table .tablehead-cell2 p {
    text-align: center;
    border-bottom: none;  
    margin-bottom: 0px;
}
.baseline-disease-table li.desk.mob-smo {
    height: 54px;
}
.baseline-disease-table .cell ul li:nth-child(3) {
    border-right: 0px solid #80a1d4;
} 
.baseline-disease-table .cell p.cellhead-2 {
    text-align: center;
    margin-bottom: 0;
    border-top: 1px solid #80a1d4;
    border-bottom: 0px solid #80a1d4;
    border-left: 0px solid #80a1d4;
    border-right: 0px solid #80a1d4;
}

.baseline-disease-table .cell ul li:first-child {
    border-left: 0px solid #80a1d4;
    text-align: left;
    padding-left: 8px;
}
.baseline-disease-table .cell ul li:nth-child(2n) {
    background-color: transparent;
}
.baseline-disease-table .cell ul li.never.unknown:first-child {
    border-left: 1px solid #80a1d4;
    text-indent: 0px;
    padding-left: 3px;
}
.baseline-disease-table .cell ul li.never:nth-child(3) {
    border-right: 1px solid #80a1d4;
}
.baseline-disease-table .disease-table {
    clear: both;
         margin-bottom: 55px;                   
}
.baseline-disease-table .cell ul li.never:nth-child(2n) {
    border-bottom: 1px solid #80a1d4;
}
.baseline-disease-table .table-body {
    border-left: 1px solid #80a1d4;
    border-right: 1px solid #80a1d4;
}
.baseline-disease-table .cell ul li.never:nth-child(2n-1) {
    border-bottom: 1px solid #80a1d4;
}
.baseline-disease-table .cell ul li{text-align: center;width: 33.33%;}        
.baseline-disease-table .cell ul {
    border-bottom: 1px solid #80a1d4;
    clear: both;
    padding: 0;
    margin: 0;
}
.baseline-disease-table ul li::before {
    content: '';
}
/*table*/
b.pinkvar{
    color: rgb(255, 0, 255);
	font-size: 20px;
}
.roleof-pdl1.roleofpdl1  .movie.section{
	display: none;
}
.li-overall-survival{
    font-weight:400;
    font-size:17px;
    color:#ac182e;
    font-family:'RobotoCondensed-Regular', sans-serif;
}
span.os-text.li-ovall{
    font-family:RobotoCondensed-Bold, sans-serif;
}
.dgr-sup{
    left:1px
}
p.footnote.ftn-indx{
    text-indent:-6px
}
.callout-content-hide{
    display:none
}
.no-break{
    white-space:nowrap
}
.marginTop{
    margin-top:-2em
}
.dis_block{
    display:block
}
.textIndent{
    text-indent:-5px;
    margin-left:5px
}
.subpage-banner{
    background-image: url(/content/dam/website-services/us/434-imfinzi-com/hcp-lung-cancer/Mobile/subpage_oceanbg_mob.png);
    background-size: 100% 100%;
    background-repeat:no-repeat;
    height: 103px;
    background-position:center center;
    margin:0 -10px
}
.subpage-banner .content-title{
    width:100%;
    margin:0 auto;
    display:table;
    height:100%;
    padding:25px 35px 0 35px
}
.subpage-banner .content-title h2{
    margin:0;
    display:table-cell;
    vertical-align:middle;
    font-size:34px;
    color:#ac162c;
    font-family:Solex, sans-serif;
    line-height:1.2;
    text-align:center;
    text-transform:uppercase
}
.page-content h2{
	font-family:'RobotoCondensed-Bold', sans-serif;
    color:#b02136;
    padding-left:13px;
    padding-top:.7em;
    margin-top:0;
    margin-bottom:.9em;
    text-indent:-9px;
    font-size:23px
}
h2.page-mark:before{
    content:" ";
    background-image:url(/content/dam/website-services/us/434-imfinzi-com/hcp-lung-cancer/Mobile/ic-cta-lung-blue.svg);
    width:30px;
    height:29px;
    background-repeat:no-repeat;
    left:-5px;
    top:8px;
    display:inline-block;
    position:relative;
    background-size:100%
}
.effImage img{
    width:100%;
}
p.imfinzi_package{
    width: 70%;
    margin: 0 auto;
}
p.imfinzi_package img{
    width: 100%;
}
.warningsandpre{
    font-family:'Roboto-Bold'!important;
    line-height:1.31;
    margin-top:30px
}
.warningsandpre a{
    color:#003865;
    text-decoration:underline
}
ul,li{
    font-family:'Roboto-Light', sans-serif;
    font-weight:300;
    font-size:16px;
    line-height:1.56;
    color:#555;
    list-style-type:none
}
ul.study-designs{
    padding-left:15px;
    margin-bottom:1.5em
}

ul.study-designs-CG {
    clear: both;
}

.Immune-Mediated ul{
    margin-bottom:0
}
.page-content.dose-modification ul.study-designs{
    padding-top:15px;
    margin-bottom:0
}
ul.study-designs li::before,ul.study-designs ul li::before{
    content:'\2022';
    position:absolute;
    color:#00b09b;
    font-size:3em;
    left:-.4em;
    top:0
}
.studydesign-sec.pfs-improve ul.study-designs li::before{
    content:''
}
.studydesign-sec.pfs-improve ul.study-designs li{
    color:#7099d3;
    font-family:'Roboto-Medium', sans-serif;
    font-size:18px
}
.studydesign-sec.pfs-improve .Secondary .study-designs{
    border-left:1px solid #979797
}
ul.study-designs li{
    margin-bottom:.5em;
    text-indent:0;
    padding-left:.4em
}
ul.study-designs li,ul.study-designs ul li{
    list-style-type:none;
    position:relative
}
p.footnote.footnote1{
    text-indent: -11px;
    padding-left: 1px;
}
p.footnote,p.chart-footnote{
    text-indent:-5px;
    padding-left:0;
    font-size:13px;
    line-height:20px;
    margin-bottom:2px;
    color:#555
}
p.footnote.double-astreik{
    text-indent:-10px
}
p.footnote.no-intent{
    text-indent:0
}
.responserates .footnote.margintop{
    margin-top:0em
}
.footnote.margintop{
    margin-top:1.7em
}
p.footnote sup{
    font-size:9px;
    top:-.5em;
    padding-right:1px
}
p.footnote sup.asterisk{
    font-size:10px;
    top:-.2em
}
.asterisk{
    font-size:12px;
    top:-.1em
}
.Gradient-divider,.Gradient-clear{
    padding:10px 0 0 0;
    background:linear-gradient(rgba(255,255,255,.7),rgba(247,247,247,.7));
    margin:0 -10px 10px -10px;
    clear:both
}
span.linebreak{
    float:none!important;
    white-space:nowrap
}
.footnote.textindent{
    text-indent:0
}
sup.aster1{
    top:-.3em
}
.immune-response-sec .flex-center{
    margin-bottom:11px;
    border: 1px solid #7099d3;
}
.immune-response-sec .right-content p{
    line-height:20px;
    margin-bottom:0
}
.immune-response-sec .right-content .red-text{
    font-family:'Roboto-Bold', sans-serif;
    color:#ac162c
}
.immune-response-sec .left-img img{
    max-width:206px
}
.first .left-img img{
    border-top-left-radius:10px
}
.flex-center.third{
    border-bottom-left-radius:10px;
    border-bottom-right-radius:10px
}
.enhance-immune .callout-content{
    text-align:center;
    padding:22px 74px 22px 74px
}
.calloutBrouchure.enhance-immune{
    margin:15px 0 29px 0
}
.calloutBrouchure.enhance-immune p{
    font-size:20px;
    margin-bottom:0
}
.regimen-head{
    background-color:#002650;
    color:#fff;
    text-align:center;
    font-size:22px;
    font-family:'RobotoCondensed-Regular', sans-serif;
    padding-top:4px;
    padding-bottom:4px;
    margin-right:26px
}
.pacific-regimen-chart .flex-start{
    margin-top:17px
}
.pacific-regimen-chart .left-div{
    padding-right:70px;
    padding-left:70px;
    background-color:#009B86;
    color:#fff;
    text-align:center;
    font-family:'HelveticaNeueLTStd-Cn', sans-serif;
    font-size:17px;
    width:38.8%;
    max-width:283px;
    height:121px
}
.pacific-regimen-chart{
    display:block;
    text-align:center;
    margin-bottom:19px;
    margin-top:22px
}
.pacific-regimen-chart img{
    max-width:100%
}
.pacific-regimen-chart .left-div span{
    display:block
}
.pacific-regimen-chart .left-div>span:first-child{
    font-size:15px;
    margin-top:7px;
    line-height:16px
}
.pacific-regimen-chart .left-div>span:nth-child(2){
    font-size:54px;
    font-family:'RobotoCondensed-Bold', sans-serif;
    margin-top:-12px
}
.pacific-regimen-chart .left-div>span:nth-child(2) sup{
    font-size:34px;
    font-family:'RobotoCondensed-Bold', sans-serif;
}
.pacific-regimen-chart .left-div>span:nth-child(3){
    margin-top:-15px;
    margin-bottom:10px
}
.pacific-regimen-chart .right-div{
    width:60%;
    max-width:435px;
    height:121px;
    background-image:url(/content/dam/website-services/us/434-imfinzi-com/hcp-lung-cancer/Path.svg);
    background-size:contain;
    background-repeat:no-repeat;
    margin-left:15px;
    color:#fff;
    text-align:center;
    font-family:'HelveticaNeueLTStd-Cn', sans-serif;
    padding-top:3px
}
.pacific-regimen-chart .right-div span{
    display:block
}
.pacific-regimen-chart .right-div span:first-child{
    font-size:54px;
    font-family:'RobotoCondensed-Bold', sans-serif;
}
.pacific-regimen-chart .right-div span:nth-child(2){
    font-size:16px;
    margin-top:-12px
}
.pacific-regimen-chart .right-div span:nth-child(3){
    font-size:12px
}
.calloutBrouchure.nccn-category{
    margin:3px 0 29px 0;
    text-align:center
}
.nccn-category .callout-content{
    padding-top:10px;
    padding-bottom:5px
}
.nccn-category .callout-content p:first-child{
    font-family:'Roboto-Bold', sans-serif;
    font-size:25px;
    margin-bottom:5px
}
.nccn-category .callout-content p:nth-child(2){
    font-size:20px
}
.roleofpdl1 .movie.section{
    margin:20px auto;
    max-width:710px;
    position:relative
}
.roleofpdl1 .movie.section .kWidgetIframeContainer{
    max-height:450px
}
.roleofpdl1 .movie.section .moviethumb img{
    width:708px!important;
    height:100%!important;
    margin:0 auto;
    display:block;
    cursor:pointer
}
.roleofpdl1 .moviethumb img{
    max-width:100%
}
.roleofpdl1 .movie.section .kWidgetIframeContainer{
    width:100%!important;
    max-height:200px;
    display:none
}
ul.subpage-list ul{
    padding-left:40px
}
.Overall-survival-chart{
    margin-bottom:47px
}
.Overall-survival-chart img{
    max-width:100%
}
ul.study-designs.Median-duration{
    padding-top:0;
    margin-bottom:29px
}
ul.study-designs.Median-OS{
    padding-top:0;
    margin-bottom:18px
}
.progressionfree-chart img{
    max-width:100%
}
ul.study-designs.PFS-month{
    padding-top:0
}
.Clinical-guidelines-chart{
	margin-bottom: 20px;
    margin-top: 30px;
}
.Clinical-guidelines-chart img{
    max-width:100%;
}
.calloutBrouchure.NCCN-Category{
    margin:20px 0 24px 0
}
.calloutBrouchure.clinically-approx p{
    text-align:center;
    padding-top:12px;
    padding-bottom:5px;
    padding-left:3px;
    padding-right:3px
}
.calloutBrouchure span.NCCN-content-bold{
    color:#ac162c;
    font-family:'Roboto-Bold', sans-serif;
}
.calloutBrouchure p span.text-nowrap{
    color:#003865;
}
.See-Study-Design a{
    text-decoration:underline
}
.Standard-care-chart{
    text-align:center;
    margin-top:20px;
    margin-bottom:40px
}
.PACIFIC-Regimen-chart{
    text-align:center;
    margin-bottom:16px;
    margin-top:13px
}
.PACIFIC-Regimen-chart img{
    max-width:100%
}
.baseline-chart{
    margin-bottom:20px
}
.baseline-chart img{
    max-width:100%
}
ul.inner-list{
    padding-left:28px
}
ul.study-designs ul.inner-list li:before{
    content:"○";
    left:-9px;
    font-size:13px;
    top:0
}
.efficacy .calloutBrouchure p, .dosing .calloutBrouchure .nccn-new .right-div p{
    font-size:16px
}
.efficacy .callout-image{
    width:30%
}
.progressionfree-sec a.study-design{
    font-family:'RobotoCondensed-Regular', sans-serif;
    text-decoration:underline;
    color:#7099d3
}
.progressionfree-sec .nsclc-pfs{
    margin-top:2em;
    margin-bottom:1.25em
}
.progressionfree-sec .clinical-trials-patients{
    margin-bottom:1.3em
}
.calloutBrouchure.nccn{
    margin:20px 0 20px 0
}
.footnote.National{
    text-indent:0;
    margin-top:10px
}
.efficacy .callout-image.nccn-image{
    height:69px;
    background-repeat:no-repeat;
    background-position:center top;
    background-size:contain;
    top:-46px
}
.nccn .first-sec{
    margin-top:-44px;
    margin-bottom:5px;
    padding-left:20px;
    padding-right:20px;
    padding-bottom:9px;
    text-align:center
}
.greyish-brown{
    color:#555555!important
}
.efficacy .calloutBrouchure .greyish-brown{
    font-size:16px;
    line-height:25px
}
.durable-response-rate img{
    width:60%;
    margin-bottom:1.6em
}
.studydesign-sec .calloutBrouchure.first{
    margin-top:35px;
    margin-bottom:25px;
    float:none
}
.studydesign-sec .page-sub-title em{
    font-family:'RobotoCondensed-Regular', sans-serif;
}
.calloutBrouchure.np-notebook{
    margin-top:5em;
    margin-bottom:1em
}
.callout-image.np-notebook-image{
    background:#fff url(/content/dam/website-services/us/434-imfinzi-com/hcp-lung-cancer/np-notebook.svg);
    height:84px;
    background-repeat:no-repeat;
    background-position:center top;
    background-size:contain;
    top:-46px
}
.calloutBrouchure.np-notebook a{
    display:inline
}
.efficacy .calloutBrouchure.np-notebook a{
    white-space:nowrap
}
.calloutfootnote{
    font-size:13px!important;
    color:#555555!important;
    line-height:20px!important;
    font-family:'Roboto-Light'!important
}
.np-notebook .first-sec{
    margin-top:-26px;
    margin-bottom:10px;
    padding-left:20px;
    padding-right:20px;
    padding-bottom:9px;
    text-align:center
}
.Gradient-divider.studyDesign{
    padding-bottom:10px;
    margin-bottom:15px
}
.Gradient-divider.RecommendedDosing{
    padding-bottom:10px
}
.Gradient-divider.dose-modify{
    padding-bottom:8px
}
.Gradient-divider.Immune-Med{
    padding-top:0
}
.Gradient-divider.PatientCharacteristics{
    margin-bottom:15px;
    padding-top:20px
}
.Gradient-divider.DurationResponse{
    padding-top:24px
}
.Gradient-divider.ObjectiveResponse{
    padding-top:1.5em
}
.nsclc-pacific{
    margin-top:1.5em
}
.efficacy .responserates .first-sec{
    text-align:center;
    padding:3px 16%
}
.efficacy .responserates .calloutBrouchure{
    margin:10px 0 20px 0
}
.efficacy .responserates .calloutBrouchure p.fact{
    font-size:30px;
    font-weight:700;
    margin-bottom:-2px;
    font-family:'Roboto-Bold', sans-serif;
}
.efficacy .responserates .chart-header.first{
    width:50%
}
.efficacy .responserates .callout-content sup{
    top:-15px
}
.efficacy .responserates ul.study-designs{
    margin-top:0;
    margin-bottom:1.5em;
    padding-right:0em;
    padding-left:15px;
    padding-top:5px
}
.efficacy .responserates ul.study-designs.secondlink{
    margin-top:0;
    margin-bottom:1.5em;
    padding-left:0;
    padding-top:5px
}
.efficacy .responserates .right-callout p.fact{
    color:#9b9b9b
}
.efficacy .responserates .first-sec.side_border .fact_text{
    color:#4e4e4b
}
.efficacy .responserates .fact_text{
    font-size:18px!important
}
.efficacy .responserates .vs{
    margin-top:-1em
}
.efficacy .responserates ul.study-designs.firstlink{
    border-bottom:1px solid #9b9b9b;
    height:100px;
    margin-bottom:3px
}
.probability-chart .lesions{
    margin-left:-11px
}
.progressionfree-sec .chart-header em{
    padding-right:3px
}
.double-asterisk{
    margin-left:-2px;
    text-indent:-8px
}
.safety .Gradient-divider.AdverseEvents{
    padding-top:22px;
    margin-bottom:9px
}
.safety .Gradient-divider.lab-Abnormal{
    padding-top:20px;
    margin-bottom:10px
}
.safety .calloutBrouchure{
    float:left;
    margin:50px 0 46px 0
}
.calloutBrouchure.icbook-image{
    margin-top:100px
}
.callout-content{
	border: 1px solid #7099D3;
    width: 100%;
    border-left: 16px solid #9E2A33;
}
.NCCN-Category .callout-content.nccn-new {
  border:none;
}
.callout-content.nccn-new .NCCN-content {
    padding: 10px 0 10px 0;
}
.efficacy .calloutBrouchure .left-div p:first-child, .dosing .calloutBrouchure .nccn-new .left-div p:first-child {
    font-size: 45.48px;
    color: #003865;
}
.efficacy .calloutBrouchure .left-div p:nth-child(2), .dosing .calloutBrouchure .nccn-new .left-div p:nth-child(2) {
    font-size: 21px;
    margin-top: -17px;
    color: #003865;
}
.NCCN-Category .callout-content.nccn-new .NCCN-content{
    border-top: 1px solid #7099d3;
    border-radius: 0px;
    width: 100%; 
    border-bottom: 1px solid #7099d3;
 }
.callout-content.nccn-new .NCCN-content {
    display: flex;
    align-items: center;
    padding: 15px 15px 10px 15px;
}
.callout-content.nccn-new .NCCN-content .right-div {
    text-align: left;margin-left: 30px;
}
.block p {
    color: #003865;
    font-family: 'Roboto-Medium', sans-serif;
        margin: 0;
}
.table-blocks .block {
    width: 100%;
    padding: 10px 18px;
    text-align: center;
    border-bottom: 1px solid #003865;
}
.block.last {
    border: none;
}
.calloutBrouchure .right-div p span.text-nowrap {
    color: #003865;
}
.NCCN-content .right-div p {
    color: #003865;
}
.NCCN-content .left-div p {
    font-family: 'RobotoCondensed-Bold', sans-serif;
}
.safety .callout-image.icbook{
    background:#fff url(/content/dam/website-services/us/434-imfinzi-com/hcp-lung-cancer/Desktop/handbook_2x.png);
    height:91px;
    background-repeat:no-repeat;
    background-position:center top;
    background-size:contain;
    top:-45px;
    width:24%
}
.safety .callout-image.ligHouse{
    background:#fff url(/content/dam/website-services/us/434-imfinzi-com/hcp-lung-cancer/Mobile/ic-lighthouse.svg);
    width:69%;
    top:-78px;
    height:91px;
    background-size:100% 100%;
    background-repeat:no-repeat;
    background-position:center top
}
.safety .calloutBrouchure-light p.ligHou{
    padding:0em 1em 1em 1em;
    margin-top:-57px
}
.safety .calloutBrouchure.calloutBrouchure-light{
    margin-bottom:30px;
    margin-top:105px
}


.calloutBrouchure p span.calling-number,
.calloutBrouchure p span.calling-number span
{
    color: #ac182e;
        font-family: 'Roboto-Bold', sans-serif;
}

.safety .calloutBrouchure a.hometel,
.dosing .calloutBrouchure a.hometel
{
	text-decoration: none;
    color: #ac182e;
   
}

.safety .callout-image{
    position:relative;
    display:block;
    margin-left:auto;
    margin-right:auto
}
.chart-header:before{
    right:100%
}
.chart-header:after{
    left:100%
}
#chart-sur-line:before,#chart-sur-line:after{
    width:3%!important
}
.overall-survival .chart-header:before,.overall-survival .chart-header:after{
    width:12%
}
.chart-header{
    text-align:center;
    font-size:13px;
    color:#003865;
    font-family:'RobotoCondensed-Bold', sans-serif;
    display:table;
    position:relative;
    width:75%;
    margin-left:auto;
    margin-right:auto;
}
.vs{
    font-size:14px;
    font-family:'Roboto-Light', sans-serif;
    background:#fff;
    color:#4e4e4b;
    left:50%;
    margin-left:-1.15em;
    margin-top:.7em;
    padding:0 .5em 0 .5em;
    position:absolute;
    text-transform:uppercase
}
.multiply{
    color:#bd0fe1
}
.safety .first-sec{
    margin-top:-1.5em;
    float:left;
    width:50%;
    height:79px;
    border-bottom:0
}
.imaeunderline{
    text-decoration:underline
}
.first-sec .fact_text{
    font-family:'Roboto-Light', sans-serif;
    color:#4e4e4b;
    font-size:18px
}
.Gradient-divider.Discon-Rate{
    padding-top:0;
    margin-bottom:10px
}
.safety .Discontinuation-Rate .callout-content{
    float:none;
    width:100%;
    max-width:100%;
    height:144px
}
.safety .Discontinuation-Rate .calloutBrouchure{
    width:100%;
    margin:10px 0 30px 0
}
.safety .Discontinuation-Rate .callout-content .ligHou{
    margin-top:13px;
    font-size:18px;
    font-weight:700;
    line-height:1.25;
    color:#003865
}
.safety .Discontinuation-Rate .calloutBrouchure .vs{
    background-size:100% 100%;
    margin-left:-.45em;
    margin-top:-1.4em;
    height:75px;
    border-left: 1px solid;
    color: #7099d3;
}
.safety .Discontinuation-Rate .calloutBrouchure .vs:before,.safety .Discontinuation-Rate .calloutBrouchure .vs:after{
    display:none
}
.safety .Discontinuation-Rate .calloutBrouchure .side_border{
    border-right:none
}
.safety .first-sec .firstlink{
    padding-right:50px;
    float:right
}
.safety .first-sec .secondlink{
    padding-left: 115px
}
.safety .first-sec .fact{
    font-size:47px;
    font-weight:700;
    margin-bottom: -2px;
    font-family:'Roboto-Bold', sans-serif;
}
.safety .first-sec.right-callout .fact{
    color:#9b9b9b
}
.side_border{
    border-right:1px solid #d8d8d8
}
.calloutBrouchure{
    float:left;
    margin:50px 0 46px 0;
    width:100%
}
.calloutBrouchure p .no-wrap{
    color:#ac162c
}
.calloutBrouchure p{
    color:#003865;
    line-height:normal;
    font-family: 'RobotoCondensed-Bold', sans-serif;
}
.calloutBrouchure p.ligHou{
    font-family:'Roboto-Medium', sans-serif;
    color:#ac182e;
    font-size:16px;
    text-align:center;
    margin-top:-32px;
    padding:1em 1em 1em 1em
}
.responserates .calloutBrouchure p.ligHou{
    margin-top:0;
    padding-bottom:0
}
.calloutBrouchure p span{
    color:#555
}
.btc-hcp .calloutBrouchure p span{
    color:#FFF;
}
.dowNo.newline{
    display:block
}
.calloutBrouchure p a{
    color:#7099d3;
    text-decoration:underline;
    font-family:'Roboto-Medium', sans-serif;
    cursor:pointer;
    display:inline
}
.callout-image.efficacy-bullets{
    width:15%!important
}
.content-title h2:before{
    content:" ";
    background-image:url(/content/dam/website-services/us/434-imfinzi-com/hcp-lung-cancer/Desktop/IMFINZI_lung_icon.svg);
    width:9px;
    height:30px;
    background-repeat:no-repeat;
    left:-8px;
    top:0;
    display:inline-block;
    position:relative;
    background-size:100% 100%;
    margin-left:-5px
}
p.immune_adverse_chrt{
    margin-bottom:1.5em;
    margin-top:1.6em
}
.dose-interrupt .callout-content{
    margin-top:30px
}
.RecommendedDosing .foornotes{
    margin-top:17px;
    margin-bottom:17px
}
.calloutBrouchure p.interrup-text{
    margin-bottom:0;
    padding:25px 80px 25px 80px;
    text-align:center;
    font-size:20px
}
.accessReimb .dowNo a{
    cursor:pointer
}
.RecommendedDosing .calloutBrouchure{
    margin-bottom:0
}
.callout-content-dosing p{
    margin-bottom:0;
    padding:1em 1.4em 1em 1.4em;
    text-align:center
}
.callout-red-copy{
    display:block;
    font-size:20px;
    color:#ac182e;
    font-family:'Roboto-Medium', sans-serif;
}
.callout-image{
    position:relative;
    margin:0 auto;
    display:block
}
.callout-image.how-to-order{
    width:75%;
    top:41px;
    height:101px;
    background-size:cover;
    background-repeat:no-repeat;
    background-position:center top;
    background:#fff url(/content/dam/website-services/us/434-imfinzi-com/hcp-lung-cancer/Desktop/imfinzi-package-insert.png);
    background-size:100% 100%
}
.imfinzi-durvalumab-dosage .content-title h2:before{
    content:" ";
    background-image:none
}
p.lung-callout-copy{
    margin-bottom:0;
    color:#ac182e;
    text-align:center;
    font-family:'Roboto-Medium', sans-serif;
}
p.howToOrder{
    padding:3em 3em 1em 3em
}
.howToOrder a,a.pi-link{
    color:#7099d3;
    text-decoration:underline
}
.dosing-chart img,.preparation-storage-administration img{
    width:100%
}
.dosing-pi-copy{
    font-family:'Roboto-Bold', sans-serif;
    font-size:16px;
    color:#555;
    padding:.4em 0;
    line-height:25px
}
.footnote-dosing{
    font-family:'Roboto-Light', sans-serif;
    font-size:13px;
    line-height:20px;
    color:#555;
    margin-bottom:3px
}
.preList{
    padding-left:0
}
ul.preList li{
    margin-bottom:1.2em;
    float:left;
    width:100%;
    text-indent:0
}
ul.preList li span{
    float:left
}
ul.preList li p{
    padding-left:3em;
    margin-bottom:0em;
    min-height:2em
}
.preparation-storage-administration ul.preList li:before{
    content:" "
}
.callout-image.lighthouse-image{
    background:#fff url(/content/dam/website-services/us/434-imfinzi-com/hcp-lung-cancer/Mobile/ic-lighthouse.svg);
    width:69%;
    top:14px;
    height:91px;
    background-size:100% 100%;
    background-repeat:no-repeat;
    background-position:center top
}
.callout-image.access-image{
    background:#fff url(/content/dam/website-services/us/434-imfinzi-com/hcp-lung-cancer/Mobile/how-to-order-imfinzi-1-3-x@2x.png);
    max-width:133px;
    width:100%;
    top:39px;
    height:102px;
    background-size:cover;
    background-repeat:no-repeat;
    background-position:center top
}
.page-content.lighthouse-access{
    margin-top:100px
}
.imfinzi-durvalumab-dosage .calloutBrouchure p{
    line-height:25px
}
p.lightHouse{
    padding:2em 1em 1em 1em
}
p.accessReimb{
    padding:4em 2em 3em 2em
}
.calloutBrouchure.access-reimbursement,.calloutBrouchure.marginTop,.calloutBrouchure.lightHouse-brochure{
    margin:0
}
.calloutBrouchure.lightHouse-brochure{
    margin-top:-1em
}
.calloutBrouchure.marginTop{
    margin-bottom:80px
}
.calloutBrouchure .lightHouse a,.calloutBrouchure .howToOrder a{
    display:inline
}
sup{
    font-size:12px;
    top:-.5em
}
.lung-cancer-tag-line-container sup{
    top:-.4em;
    font-size:75%
}
h3.page-sub-title{
    font-size:20px;
    font-style:normal;
    font-stretch:condensed;
    line-height:1.25;
    letter-spacing:normal;
    text-align:left;
    margin:15px 0 20px 0;
    color:#003865;
    font-family:'RobotoCondensed-Bold'!important
}
.mobile-align{
    display:block;
    text-indent:.8em
}
.Withdraw span.no-wrap{
    float:none
}
ul.study-designs li::before,ul.study-designs ul li::before{
    color:#00ae9b
}
.effImage{
    margin-bottom:30px
}
.dosing-page ul.study-designs{
    margin-bottom:1.5em
}
.dosing-page .callout-content{
    margin-bottom:30px
}
.calloutBrouchure.marginTop{
    margin-top:-2em
}
.preparation-storage-administration ul.preList li p{
    margin-bottom:.5em;
    margin-top:-5px
}
.lighthouse-access p.lightHouse span{
    color:#ac182e
}
.calloutBrouchure.access-reimbursement{
    margin-bottom:30px!important
}
.dosing-pi-copy a{
    color:#7099d3;
    text-decoration:underline
}
.safety-chart-two img.desktop_only{
    width:100%
}
.safety-chart-two img.mobile_only{
    width:100%
}
.treating-imfinzi-sec h2.wrapLine sup{
    top: -8px;
}
.imfinzi-crt .subpage-banner h2 sup{
	font-family: 'RobotoCondensed-Bold', sans-serif;
}
.chart_footnote .textIndent1{
	text-indent: -5px;
}
.chart_footnote .textIndent1 sup{
	font-size: 75%;
}

/******FPO**************/

.watermark{
    position: relative;
    }

.watermark h4{
    position: absolute;
    top: 120px;
    left: 330px;
    transform: rotate(-50deg);
    color: #ff008d;
    font-size: 40px;
    font-weight: 700;
    font-family: 'RobotoCondensed-Bold', sans-serif;
    opacity: 0.5;
        }

	.refmark h4{
    top: 110px;
    left: 48%;
}

    .livetext-mark h4{
    top: 15px;
    font-size: 30px;
    }

@media screen and (max-width:767px){
/*********************************US-52438********************************************************/
a#or-decker{
    scroll-margin-top: 90px !important;
}
.subpage-banner .content-title{
	padding: 10px 35px 0 35px !important;
}
p.hColor{
    font-size: 12px;
	line-height: 15px;
}
span.sec-header {
    font-size: 13px;
    padding: 5px 9px;
}
h1.page-sub-title{
	font-size: 19px;
    line-height: 22px;
}
.hombanner-section .crt-subhead sup{
	top: -0.25em;
}
h1.page-sub-title.sec1 sup{
    top: -.6em;
}
.chart-header{
	font-size: 17px;
	width: 100%;
}
.efficacy  h1.page-sub-title.mobile-reduce{
	margin-bottom: 5px;
}
.efficacy img{
	max-width: 100%;
	margin: 0 auto;
}
.efficacy .twoyear-primary img, .efficacy .fiveyear-posthoc img, .efficacy .oneyear-primaryos img, .efficacy .fiveyear-posthocPFS img{
	width: 95%;
}
.newcallout-design {
	padding: 12px 0 12px 20px !important;
    text-align: left !important;
}
.newcallout-design p{
	font-size: 20px !important;
    padding-right: 15px !important;
    line-height: 22px !important;
}
.efficacy .overall-survival-sec .calloutBrouchure.enhance-immune{
    margin: 10px 0 16px 0;
}
div#myEmbedTarget_1_ydc0qzp0, div#myEmbedTarget_1_zx1dijuz {
    max-width: 100%;
    width: 333px !important;
    max-height: 183px !important;
}
.efficacy .socinski-video, .efficacy .roydecker-video {
    margin-bottom: -5px;
}
.efficacy .progressionfree-sec h1.page-sub-title.reduceSpace{
    margin: 11px 0 35px 0;
}
.efficacy h1.page-sub-title.one-third{
	margin-top: 32px;
}
.efficacy .progressionfree-sec .calloutBrouchure.enhance-immune{
    margin: 19px 0 23px 0;
}
.imfinzicrt .treating-table{
	display: block;
    margin-top: 20px;
	padding: 0 10px;
    border: 1px solid #7099D3;
}
.imfinzicrt p.treating-subhead {
    font-family: 'RobotoCondensed-Bold', sans-serif;
    font-size: 19px;
	line-height: 22px;
}
.imfinzicrt  .treating-table .leftText{
    border-bottom: 2px solid red;
    padding: 15px;
}
.imfinzicrt  .treating-table .rightText{
    padding: 15px;
}
.safety .discon-rate-imgsec{
	margin-top: 20px;
    margin-bottom: 36px;
}

/*********************************US-52438 End********************************************************/
.watermark h4{
	position: absolute;
    top: 30px;
    left: 175px;
    transform: rotate(-50deg);
    color: #ff008d;
    font-size: 20px;
    font-weight: 700;
    font-family: 'RobotoCondensed-Bold', sans-serif;
    opacity: 0.5;
                }

    .refmark h4{
    top: 40%;
    font-size: 30px;
    left: 43%;    
                }

.page-head{
        display: flex;
        width: 80%;
            }
.page-head1 {
        display: flex;
            width: 300px;
                }

h2.page-head:before{
        width: 30px;
        max-width: 100%
                }
h2.page-head1:before{
        width: 52px;
        height: 33px;
                }

.Standard-care-chart.watermark h4{
	position: absolute;
    top: 185px;
	left: 210px;                        
    }

	/***********New Code**********/
     span.aste {
    top: -3px;
    position: relative;
}
	.Discontinuation-Rate p.mobile_only img{
		width: 100%;
		margin-bottom: 10px;
	}
	.dosing-page.RecommendedDosing h2{
		text-indent: -31px;
		padding-left: 35px;
	}
	p.tablehead-header{
	    padding: 0;
	}
	.base-table .chart-header{
	    margin-top: 20px;
	}

.safety .first-sec.right-callout .fact_text{
    margin-left: -10px;
}
	.base-table .table-body{
	    margin-bottom: 60px;
	}
	.imfinzi-crt .subpage-banner h2 sup{
		font-size: 16px;
		top: -12px;
	}
	.NCCN-Category .callout-content.nccn-new .NCCN-content{
		padding: 15px 5px 10px 5px;
	}
	.callout-content.nccn-new .NCCN-content .left-div{
		width: 33%;
    	margin-bottom: 30px;
	}
	.callout-content.nccn-new .NCCN-content .right-div{
		margin-left: 10px;
		width: 67%;
	}
    .studydesign-sec .studydesign-chart img.mobile-graph{
        max-width: 355px;
        padding-bottom:20px;
    }
	.effImage img{
		margin: 0 auto;
        width: 297px;
	}
	.Overall-survival-chart img{
	    margin-top: -30px;
	}
	.baseline-disease-table .tablehead-cell1 p, .baseline-disease-table .tablehead-cell2 p{
		margin-top: 5px;
		padding: 0;
	}
	/***********New Code End *********/
    .immune-response-sec .left-img img{
        max-width:100%
    }
    .immune-response-sec .flex-center{
        display:block;
        max-width:450px;
        margin-left:auto;
        margin-right:auto
    }
    .immune-response-sec .right-content{
        padding-left:15px;
        padding-bottom:15px;
        padding-right:31px
    }
    .immune-response-sec .right-content p:first-child{
        margin:0 auto;
        margin-bottom:8px
    }
    .first .left-img img{
        border-top-left-radius:10px;
        border-top-right-radius:10px
    }
    .enhance-immune .callout-content{
        padding:17px 40px 20px 40px

    }
    .calloutBrouchure.enhance-immune{
        margin:15px 0 8px 0
    }
    .regimen-head{
        margin-right:31px
    }
    .pacific-regimen-chart .left-div{
        padding-right:0;
        padding-left:0
    }
    .pacific-regimen-chart .right-div{
        margin-left:8px
    }
    .pacific-regimen-chart .right-div{
        background-image:url(/content/dam/website-services/us/434-imfinzi-com/hcp-lung-cancer/Mobile/Path-mobile.png);
        background-size:100% 100%;
        padding-left:14px;
        padding-right:33px;
        padding-top:12px
    }
    .pacific-regimen-chart .left-div>span:first-child{
        font-size:13px
    }
    .pacific-regimen-chart .left-div>span:nth-child(2){
        font-size:45px;
        margin-top:-10px
    }
    .pacific-regimen-chart .left-div>span:nth-child(2) sup{
        font-size:28px
    }
    .pacific-regimen-chart .left-div>span:nth-child(3){
        margin-top:-9px
    }
    .pacific-regimen-chart .right-div span:first-child{
        font-size:40px
    }
    .pacific-regimen-chart .right-div span:nth-child(2){
        font-size:14px
    }
    .calloutBrouchure.nccn-category{
        margin:20px 0 33px 0
    }
    .nccn-category .callout-content{
        padding-left:13px;
        padding-right:13px;
        padding-top:24px;
        padding-bottom:12px
    }
    .nccn-category .callout-content p:first-child{
        font-size:20px
    }
    .Gradient-divider.DurationResponse{
        padding-top:24px;
        margin-bottom:5px
    }
    .Overall-survival-chart{
        text-align:center;
    	margin-top: 45px;
		margin-bottom: 20px;
    }
	.progressionfree-chart {
    margin-bottom: 30px;
	}
    .overall-survival-sec .chart-header:before{
        right:99%;
        width:18%
    }
    .overall-survival-sec .chart-header:after{
        left:99%;
        width:18%
    }
    .PACIFIC-Regimen-sec .chart-header:before{
        right:79%;
        width:37%
    }
    .PACIFIC-Regimen-sec .chart-header:after{
        left:79%;
        width:37%
    }
    .PACIFIC-Regimen-sec .calloutBrouchure.NCCN-Category{
        margin:13px 0 24px 0
    }
    .baseline-chart img.mobile-graph.first{
        margin-bottom:15px
    }
    .studydesign-sec ul.study-designs{
        margin-bottom:0
    }
    .studydesign-sec .first .callout-content{
        padding:20px 25px 15px 25px
    }
    .studydesign-sec .first-sec.Coprimary{
        padding-bottom:11px;
        border-bottom:1px solid #7ca3dc
    }
    .studydesign-sec .first-sec.Secondary{
        margin-top:17px
    }
    .studydesign-sec .Coprimary .study-designs{
        border-bottom:none
    }
    .baseline-chart{
        text-align:center
    }
    .chart-header.ovr-sur:after{
        top:59%;
        width:26%!important;
        left:81%!important
    }
    .chart-header.ovr-sur:before{
        top:59%;
        width:26%!important;
        right:81%!important
    }
    .content-title h2:before{
        display:none
    }
    .isi ul li .newLine{
        line-height:1.31
    }
    .content-title h2:before{
        content:" ";
        width:17px;
        height:35px;
        background-repeat:no-repeat;
        left:-25px;
        top:6px;
        display:inline-block;
        position:relative;
        background-size:100% 100%;
        margin-right:-16px
    }
    .efficacy .responserates ul.study-designs{
        padding-right:0
    }
    .accordion-header{
        border-left:solid 1px #929497;
        border-top-left-radius:13.5px;
        border-right:solid 1px #929497;
        max-width:365px;
        margin:0 auto;
        position:relative
    }
    table.bg-color tr{
        background-color:#d5dff0
    }
    .accordion-list.section{
        border-left:solid 1px #929497;
        border-right:solid 1px #929497;
        border-bottom:solid 1px #929497;
        border-bottom-left-radius:14.5px;
        border-bottom-right-radius:14.5px;
        max-width:365px;
        margin:0 auto
    }
    .efficacy table td{
        font-family:'HelveticaNeueLTStd-Cn', sans-serif;
        font-size:15px;
        padding-left:6px
    }
    .efficacy table td:nth-child(2){
        border-right:solid 1px #929497;
        border-bottom:solid 1px #929497
    }
    .list-module-0.accordion-list-item h3{
        margin-top:0
    }
    .accordion-list-item.list-module-7 h3{
        border-bottom-left-radius:13.5px;
        border-bottom-right-radius:13.5px
    }
    .efficacy_accordion h3{
        font-family:'HelveticaNeueLTStd-Cn', sans-serif;
        color:#fff;
        background-color:#5f83b7;
        margin:1px 0 0 0;
        padding:.7em .7em .7em .4em;
        cursor:pointer;
        font-size:16px
    }
    .efficacy_accordion .active h3{
        background-color:#173a64;
        border-radius:0
    }
    .acc_h3_content{
        width:92%;
        display:inline-block;
        padding-right:.5em
    }
    .efficacy_accordion h3 img{
        max-width:7px;
        float:right;
        width:8%
    }
    .accordion-list h3 .openarrow{
        display:none
    }
    .accordion-list .active h3 .openarrow{
        display:block;
        max-width:16px;
        margin-top:5px
    }
    .accordion-list .active h3 .closearrow{
        display:none
    }
    .accordion-openall{
        position:absolute;
        right:0;
        width:32%;
        background-image:url(/content/dam/website-services/us/434-imfinzi-com/hcp-lung-cancer/Mobile/bkg.png);
        background-size:100% 100%;
        background-repeat:no-repeat;
        z-index:4
    }
    .accordion-openall p{
        text-align:center;
        margin-bottom:0;
        font-family:'RobotoCondensed-Bold', sans-serif;
        font-size:12px;
        color:#7099d3
    }
    .accordion-openall p img{
        width:19px;
        padding-left:5px
    }
    .accordion-openall .closeall{
        display:none
    }
    .accordion-openall.closeaccrodion .openall{
        display:none
    }
    .accordion-openall.closeaccrodion .closeall{
        display:block;
        color:#003865
    }
    .scaleimage{
        text-align:right;
        margin-right:4px
    }
    .scaleimage .numbers p{
        display:inline
    }
    .scaleimage .numbers p:first-child{
        margin-left:0
    }
    .scaleimage .numbers p:nth-child(2){
        margin-left:1.5em
    }
    .scaleimage .numbers p:nth-child(3){
        margin-left:.9em
    }
    .scaleimage .numbers p:nth-child(4){
        margin-left:1.4em
    }
    .scaleimage .numbers p:last-child{
        margin-left:2em
    }
    .scaleimage .favor-text p{
        display:inline-block;
        font-size:11px;
        line-height:11px;
        font-family:'HelveticaNeueLTStd-Cn', sans-serif;
    }
    .scaleimage img{
        width:56%
    }
    .favor-text{
        margin-top:-.7em;
        margin-right:.55em
    }
    .favor-text p:first-child{
        color:#ab162b
    }
    .favor-text p:last-child{
        color:#939598;
        text-align:left
    }
    .efficacy_accordion table,.accordion-header table{
        width:100%
    }
    .accordion-header table .patientchar-row{
        background-color:#ac162c;
        color:#fff;
        height:68px
    }
    .accordion-header table .second-row{
        color:#fff;
        text-align:center
    }
    .second-row td:first-child{
        background-color:#ac162c
    }
    .second-row td:last-child{
        background-color:#ac162c
    }
    .accordion-header .patientchar-row td:first-child{
        border-top-left-radius:13.5px;
        border-right:none;
        font-family:'HelveticaNeueLTStd-BdCn', sans-serif;
        font-size:16px;
        line-height:16px
    }
    .accordion-header .patientchar-row td:nth-child(2),.accordion-header .overall-row td:nth-child(2){
        border-bottom:solid 1px #929497;
        border-right:solid 1px #929497
    }
    .second-row p{
        font-size:13px;
        padding-top:5px;
        padding-bottom:5px;
        line-height:14px
    }
    .second-row td{
        padding-left:0px!important
    }
    .rotate p{
        padding-top:16px;
        padding-bottom:5px
    }
    .accordion-header table .overall-row{
        background-color:#5f83b7;
        color:#fff
    }
    .overall-row td:last-child img{
        margin-right:5em
    }
    .overall-row td:nth-child(2){
        font-size:14px;
        padding-left:14px
    }
    .overall-row td:last-child{
        margin-right:5em
    }
    .overall-row td:last-child img{
        margin-top:0.2em!important
    }
    .overall-row td:last-child p{
        font-size:15px;
        margin-top:-.2em;
        margin-bottom:.4em
    }
    .accordion-header table p{
        color:#fff;
        margin-bottom:0
    }
    .accordion-header .patientchar-row p{
        text-align:center;
        padding-top:1.6em;
        font-family:'HelveticaNeueLTStd-BdCn', sans-serif;
    }
    .accordion-header table td:first-child{
        width:26%;
        border-right:solid 1px #929497;
        border-bottom:solid 1px #929497
    }
    .accordion-header table td:nth-child(2){
        width:17%
    }
    .accordion-header table td:last-child{
        text-align:right;
        border-bottom:solid 1px #929497;
        padding-right:16px
    }
    .accordion-header .second-row td:nth-child(2){
        background-image:url(/content/dam/website-services/us/434-imfinzi-com/hcp-lung-cancer/Mobile/bkg-diag@3x.png);
        background-size:100% 100%;
        height:85px
    }
    .efficacy_accordion table td:first-child{
        width:27%;
        border-right:solid 1px #929497;
        border-bottom:solid 1px #929497
    }
    .efficacy_accordion table td:nth-child(2){
        width:17%;
        padding-left:0;
        position:relative
    }
    .efficacy_accordion table td:nth-child(2) p:first-child{
        position:absolute;
        margin-left:4px;
        color:#333;
        font-size:14px;
        font-family:'HelveticaNeueLTStd-Cn', sans-serif;
    }
    .efficacy_accordion table td:nth-child(2) .triangle p{
        position:absolute;
        top:23px;
        right:3px
    }
    table td p span{
        font-family:'HelveticaNeueLTStd-BdCn', sans-serif;
    }
    .efficacy_accordion table.bg-color tr:last-child td{
        border-bottom:none
    }
    .efficacy table td:last-child{
        text-align:right;
        border-bottom:solid 1px #929497;
        padding-right:16px;
        position:relative
    }
    .divdashgrey{
        height:47px;
        position:absolute;
        border-right:1px solid #616366;
        border-right-style:dashed;
        top:0;
        right:50px
    }
    .divdashgrey.divdashheight{
        height:15px
    }
    .divdashblue{
        height:47px;
        position:absolute;
        border-right:1px solid #aec1e4;
        border-right-style:dashed;
        top:0;
        right:50px
    }
    .efficacy table td:last-child img{
        margin-top:.6em
    }
    td .triangle{
        width:0;
        height:0;
        border-left:59px solid transparent;
        border-bottom:47px solid rgba(151,151,151,.3);
        position:relative
    }
    .Male td:last-child img{
        margin-right:3.75em
    }
    .Female td:last-child img{
        margin-right:3.15em
    }
    .lessthan td:last-child img{
        margin-right:3.5em
    }
    .morethan td:last-child img{
        margin-right:3.05em
    }
    .efficacy .lessthan td:last-child{
        padding-right:2.5em
    }
    .efficacy .morethan td:last-child{
        padding-right:5px
    }
    .Smoker td:last-child img{
        margin-right:3.3em
    }
    .Non-smoker td:last-child img{
        margin-right:1.7em
    }
    .efficacy .Non-smoker td:last-child{
        padding-right:4.7em
    }
    .IIIA td:last-child img{
        margin-right:3.7em
    }
    .IIIB td:last-child img{
        margin-right:3.3em
    }
    .efficacy .IIIA td:last-child{
        padding-right:1.3em
    }
    .Squamous td:last-child img{
        margin-right:3.3em
    }
    .Non-Squamous td:last-child img{
        margin-right:3.6em
    }
    .efficacy .Squamous td:last-child{
        padding-right:5px
    }
    .efficacy .Non-Squamous td:last-child{
        padding-right:2.3em
    }
    .Partial td:last-child img{
        margin-right:3.6em
    }
    .Stable td:last-child img{
        margin-right:3.6em
    }
    .greaterthan td:last-child img{
        margin-right:2.7em
    }
    .lowerthan td:last-child img{
        margin-right:3.6em
    }
    .Unknown td:last-child img{
        margin-right:3.6em
    }
    .efficacy .greaterthan td:last-child{
        padding-right:2.7em
    }
    .Positive td:last-child img{
        margin-right:1.1em
    }
    .Negative td:last-child img{
        margin-right:3.8em
    }
    .Poitive-unknown td:last-child img{
        margin-right:2.75em
    }
    .efficacy .Positive td:last-child{
        padding-right:5px
    }
    .efficacy .Negative td:last-child{
        padding-right:2em
    }
    .efficacy .Poitive-unknown td:last-child{
        padding-right:5px
    }
    .efficacy_accordion table td p{
        margin-bottom:0
    }
    .efficacy_accordion table td:last-child p{
        font-size:15px;
        font-family:'HelveticaNeueLTStd-Cn', sans-serif;
    }
    .accordion-footerinfo{
        margin-top:1em;
        padding-right:1em
    }
    .accordion-footerinfo p{
        font-size:13px;
        font-stretch:condensed;
        line-height:1.31;
        letter-spacing:-.1px;
        text-align:left;
        color:#9b9b9b;
        font-family:'HelveticaNeueLTStd-Cn', sans-serif;
    }
    .Coprimary .study-designs{
        border-bottom:1px solid #7ca3dc
    }
    .Secondary .study-designs{
        border-bottom:none
    }
    .patient-char .probability-chart{
        max-width:370px
    }
    .patient-char .probability-chart img.mobile-graph,.PatientChar-sec .nsclc-patient-baseline img{
        width:100%
    }
    .overall-survival .chart-header{
        width:86%
    }
    .overall-survival .chart-header:before,.overall-survival .chart-header:after{
        width:5%
    }
    .overall-survival .chart-header:before{
        right:102%
    }
    .overall-survival .chart-header:after{
        left:102%
    }
    .lab-Abnormalities .chart-header{
        line-height:20px
    }
    .safety .Discontinuation-Rate .callout-content .ligHou{
        margin-top:-1px
    }
    .safety .first-sec .fact{
        font-size:40px
    }
    .safety .first-sec{
        height:72px
    }
    .vs{
        font-size:13px;
        margin-top:.4em
    }
    .safety .Discontinuation-Rate .callout-content{
        height:190px
    }
    p.lightHouse{
        line-height:26px
    }
    p.accessReimb{
        padding:4em 2em 2.2em 2em;
        line-height:26px
    }
    .safety .first-sec .firstlink{
        padding-right:30px
    }
    .safety .first-sec .secondlink{
        padding-left:30px
    }
    .patient-char ul.study-designs{
        margin-top:1.5em
    }
    .calloutBrouchure p.interrup-text{
        padding:25px 20px 25px 20px;
        font-size:20px
    }
    .responserates .chart-header:before{
        right:80%;
        width:35%
    }
    .responserates .chart-header:after{
        left:80%;
        width:35%
    }
    .probability-chart .lesions{
        margin-left:20px
    }
    .lab-Abnormalities .chart-header:before,.lab-Abnormalities .chart-header:after{
        top:50%
    }
}
@media screen and (max-width:370px){
/*********************************US-52438********************************************************/
.efficacy .subpage-banner .content-title img{
    max-width: 75%;
}
a[name='isi'],a.section-link{
	display:inline-block;
	height:130px;
	margin-top:-130px;
	/*margin-top:-94px*/
}
.efficacy .calloutBrouchure .left-div p:first-child, .dosing .calloutBrouchure .nccn-new .left-div p:first-child {
    font-size: 39.5px;
}
.efficacy .calloutBrouchure .left-div p:nth-child(2), .dosing .calloutBrouchure .nccn-new .left-div p:nth-child(2){
	font-size: 18px;
}
.dosing  .sec-header-container.no-barline{
	display: flex;
}
/*********************************US-52438 End********************************************************/
    .efficacy .base-table .cell ul li{	
       padding-top: 12.9px !important;
       padding-bottom: 11.3px !important;
    }
	.base-table .cell ul li.current{
		font-size: 12.5px !important;
	}
	.baseline-disease-table p.cellhead-2, .baseline-disease-table li{
		font-size: 13px !important;
	}
	.baseline-disease-table .disease-table .table-body{
	    height: 363px !important;
	}
	.disease-table p.cellhead-2.muta{
	    height: 109px !important;
	}
	.safety .Discontinuation-Rate .callout-content{
		height: 220px;
	}
	.safety .callout-image.ligHouse{
	    top: -76px;
		background-size: 92% 100%;
	}
    .content-title h2:after{
        left:75px
    }
    .scaleimage img{
        width:51%
    }
    .scaleimage .numbers p:last-child{
        margin-left:1.4em
    }
    .scaleimage .numbers p:nth-child(4){
        margin-left:.5em
    }
    .scaleimage .numbers p:nth-child(3){
        margin-left:.2em
    }
    .scaleimage .numbers p:nth-child(2){
        margin-left:.75em
    }
    .efficacy .Non-smoker td:last-child{
        padding-right:2.6em
    }
    .accordion-header table td:nth-child(2){
        width:21%
    }
    .accordion-header table td:first-child{
        max-width:80px
    }
    .scaleimage .favor-text p{
        font-size:7.5px
    }
}
@media screen and (min-width:380px){
    .scaleimage img{
        width:54.5%
    }
}	
@media screen and (min-width:380px) and (max-width: 767px){
	.base-table p.cellhead-2.smoking{	
	    height: 153px !important;	
	}
}

@media screen and (min-width:502px) and (max-width: 767px){	
	.disease-table .cell p.cellhead-2.PD-L1{	
		height: 105px !important;
		padding-right: 5px !important;		
	}
	.baseline-disease-table .cell p.cellhead-2{
		padding-right: 2px !important;
	}
}	
@media screen and (min-width:558px) and (max-width: 767px){	
    .efficacy .base-table .cell ul li{	
       padding-top: 12px !important;
       padding-bottom: 13.3px !important;
    }	
	.efficacy .base-table .cell ul li:first-child{	
		padding-left: 2px;	
	}	
	.mob-brk{	
		display: none !important;	
	}	
	.baseline-disease-table .base-table .table-body{	
	    height: 307px !important;	
	}	
	.base-table p.cellhead-2.smoking{	
		height: 104px !important;	
		padding-top: 40px !important;	
	}	
	.base-table .cell li.desk, .baseline-disease-table .base-table .cell ul li.never.unknown{	
		height: 52px !important;	
	}	
	.base-table .cell li.desk{	
		padding-top: 15px !important;	
	}	
}
@media screen and (min-width:768px){
/*********************************US-52438********************************************************/
.hombanner-section .survival-img img.desktop_only{
    width: 430px;
    height: 290px;
}
.post-hoc-imgsec a img.desktop_only{
    width: 437px;
    height: 115px;
}
.imfinzicrt .subpage-banner .content-title img.desktop_only{
    width: 311px;
    height: 87px;
}
.imfinzicrt .treating-imfinzi-sec .pacific-regimen-chart img.desk-graph, .efficacy .fiveyear-posthoc img.desktop_only, .efficacy .fiveyear-posthocPFS img.desktop_only{
    width: 708px;
    height: 163px;
}
.imfinzicrt .treating-imfinzi-sec .survival-chart img.hidden-xs{
    width: 708px;
    height: 207px;
}
.imfinzicrt .immune-response-sec .flex-center .left-img img{
    width: 206px;
    height: 116px;
}
.efficacy  .subpage-banner .content-title img.desktop_only{
    width: 342px;
    height: 103px;
}
.efficacy .twoyear-primary img.desktop_only, .efficacy .oneyear-primaryos img.desktop_only{
    width: 708px;
    height: 123px;
}
.efficacy .Overall-survival-chart img.desk-graph{
    width: 708px;
    height: 429px;
}
.efficacy .progressionfree-chart img.desk-graph{
    width: 708px;
    height: 421px;
}
.efficacy .Clinical-guidelines-chart img.desk-graph{
    width: 708px;
    height: 255px;
}
.efficacy .Standard-care-chart img.desk-graph{
    width: 708px;
    height: 297px;
}
.efficacy .studydesign-chart img.desk-graph{
    width: 708px;
    height: 238px;
}
.safety .subpage-banner .content-title img.desktop_only{
    width: 440px;
    height: 87px;
}
.safety .discon-rate-imgsec p.desktop_only img{
    width: 708px;
    height: 141px;
}
.dosing .subpage-banner .content-title img.desktop_only{
    width: 285px;
    height: 87px;
}
.dosing .effImage img{
	width: 680px;
	height: 214px;
}
.dosing p.dosing_table img.desktop_only{
	width: 708px;
	height: 754px;
}
a#or-decker{
    scroll-margin-top: 40px !important;
}
.sec-header-container{
    border-top: 1px solid #003865;
}
.sec-header-container.no-barline{
    border-top: transparent;
}
span.sec-header {
    font-size: 15px;
    padding: 5px 9px;
}
p.hColor{
    font-size: 14px;
}
h1.page-sub-title sup{
    top: -.7em;
}
h1.page-sub-title.sec1 sup{
    top: -.9em;
}
.newcallout-design{
    padding: 15px 8px 15px 22px !important;
	text-align: left !important;
}
.newcallout-design p{
	font-size: 24px !important;
}
.hombanner-section .crt-subhead sup{
	top: -0.75em;
}
.efficacy img{
	max-width: 100%;
}
.efficacy p.hColor, .efficacy .studydesign-sec .NCCN-Category .callout-content p{
	margin-bottom: 0;
}
.efficacy h1.page-sub-title.reduceSpace{
    margin: 0px 0 15px 0;
}
.efficacy .twoyear-primary, .efficacy .fiveyear-posthoc{
	margin-bottom: 25px;
}
.efficacy .oneyear-primaryos{
	margin: 30px 0 31px 0;
}
.efficacy .fiveyear-posthocPFS{
	margin: 29px 0 34px 0;
}
.efficacy .Overall-survival-chart {
    margin-bottom: 40px;
}
.efficacy .socinski-videotext, .efficacy .roydecker-videotext{
	margin-top: 45px;
	margin-bottom: 5px;
}
.efficacy .socinski-video, .efficacy .roydecker-video {
    margin-bottom: -30px;
}
.efficacy h1.page-sub-title.one-third{
	margin: 15px 0 15px 0;
}
.efficacy .studydesign-chart img.desk-graph{
	margin-bottom: 10px;
}
.imfinzicrt .treating-table{
	display: flex;
    align-items: flex-start;
    border: 1px solid #7099D3;
    margin-top: 20px;
	padding: 10px 0;
}
.imfinzicrt p.treating-subhead {
    font-family: 'RobotoCondensed-Bold', sans-serif;
    font-size: 25px;
}
.imfinzicrt  .treating-table .leftText{
    width: 50%;
    border-right: 2px solid red;
    padding: 15px;
}
.imfinzicrt  .treating-table .rightText{
    width: 50%;
    padding: 15px;
}
.safety .discon-rate-imgsec{
	margin-top: 20px;
    margin-bottom: 45px;
}
.dosing .calloutBrouchure.NCCN-Category{
    margin: 12px 0 0px 0;
}
/*********************************US-52438 End********************************************************/

.callout-content.consider-content {
    padding: 22px 59px;
}

.safety .calloutBrouchure a.hometel,
.dosing .calloutBrouchure a.hometel
{

                cursor: auto !important;
}


.baseline-disease-table .base-table {
    width: 49%;
    margin-right: 2%;
}
.baseline-disease-table {
    display: flex;
}
.baseline-disease-table .tablehead-cell1 {
    width: 25%;
}
.baseline-disease-table .tablehead-cell2 {
    width: 25%;
}
.baseline-disease-table p.tablehead-header {
    width: 50%;
    margin-top: 37px;
}
.baseline-disease-table .table-body {
    clear: both;
     height: 360px;
}
.baseline-disease-table .cell ul li.no-bg {
    background-color: #fefefe;
    border-top: 1px solid #80a1d4;
}
.baseline-disease-table .cell ul li:first-child {
    border-left: 1px solid #80a1d4;
    text-indent: 0px;
    padding-left: 3px;
}                                        
.baseline-disease-table .cell ul li {
    text-align: center;
    width: 25%;
}
.baseline-disease-table .cell ul {
    clear: none;
}
.disease-table p.cellhead-2.stage {
    padding: 10px 0 10px 7px;
}
.baseline-disease-table .cell p.cellhead-2 {
    text-align: left;
}
.disease-table p.cellhead-2.muta {
    border-bottom: 1px solid #80a1d4;
    height: 108px;
}            
.disease-table .cell p.cellhead-2 {
 clear: both;
 }
.base-table p.cellhead-2.smoking {
    border-bottom: 1px solid #80a1d4;
    height: 154px;
    padding-top: 50px;     
}    
.base-table .cell li.desk {
    height: 77px;
    padding-top: 26px;
}
.baseline-disease-table .cell ul li.never:nth-child(3) {
    border-right: 0px solid #80a1d4;
}                            
.base-table .cell ul li {
    padding: 12.8px 0;
}                                                       
.baseline-disease-table .disease-table {
    width: 50%;
}
.page-content ul li.current {
    font-size: 14.5px;
    padding-left: 4px;
}
.baseline-disease-table p.cellhead-2 {
    width: 25%;
  padding: 23px 0 20px 7px;                                            
}
.base-table p.cellhead-2 {
    padding-top: 40px;
}
        .table-blocks {
    display: flex;
          }
        .calloutBrouchure.first .callout-content {
     border-radius: 0px; 
}
	/***********New Code**********/
	.imfinzi-crt .subpage-banner h2 sup{
		font-size: 20px;
		top: -15px;
	}
    .studydesign-sec .studydesign-chart img.desk-graph{
        max-width:710px;
    }
    .imfinzicrt .immune-response-sec .right-content {
        padding-left: 15px;
        border-left: 10px solid #ac162c;
        padding-top: 15px;
        padding-bottom: 15px;
        padding-right: 31px;
    }
    .dosing .dosing-chart.discontinue-chart {
        display: inline-block;
        margin: 0;
        padding-bottom: 0;
    }
	.callout-content.nccn-new .NCCN-content .right-div{
	    margin-top: 7px;
	}
	/***********New Code End *********/
    .lesions{
        margin-top:0;
        margin-bottom:0
    }
    ul{
        margin-bottom:25px
    }
    .footnote.doubleasterisk{
        text-indent:-11px;
        padding-left:0
    }
    .vs:before{
        content:"";
        background-color:#d8d8d8;
        position:absolute;
        width:1px;
        height:27px;
        bottom:19px;
        left:49%;
        display:block
    }
    .vs:after{
        content:"";
        background-color:#d8d8d8;
        position:absolute;
        width:1px;
        height:27px;
        top:19px;
        left:50%;
        display:block
    }
    .subpage-banner{
        background-image:url(/content/dam/website-services/us/434-imfinzi-com/hcp-lung-cancer/Desktop/subpage_oceanbg_desk.png);
        background-size:100% 100%;
        background-repeat:no-repeat;
        height:141px;
        background-position:center center;
        margin:0
    }
    .subpage-banner .content-title{
        width:708px;
        margin:0 auto;
        display:table;
        height:117px;
        padding:0 0;
        position:relative
    }
    .subpage-banner .content-title h2{
        margin:0;
        text-align:left;
        display:table-cell;
        vertical-align:baseline;
        font-size:42px;
        line-height:87px;
        color:#ac182e;
        font-family:Solex, sans-serif;
    }
    p{
        font-size:16px;
        line-height:25px;
        margin-bottom:10px;
        color:#555
    }
    p.recommended-text{
        font-family:'Roboto-bold', sans-serif;
    }
    .page-content h2{
        font-size:23px;
        line-height:40px;
        margin:0 0 10px 0
    }
    h1.page-sub-title{
        font-size:25px;
        line-height:28px;
        margin:15px 0 20px 0;
    }
    .subpage-banner .content-title h2:before{
        width:35px;
        height:75px;
        background-size:contain;
        top:22px
    }
    .immune-response-sec .right-content{
        padding-left:15px;
        padding-top:15px;
        padding-bottom:15px;
        padding-right:31px
    }
    .third .left-img img{
        border-bottom-left-radius:10px
    }
    .roleofpdl1 .movie.section .moviethumb img{
        width:708px!important;
        height:100%!important;
        margin:0 auto;
        display:block;
        cursor:pointer
    }
    .roleofpdl1 .movie.section .kWidgetIframeContainer{
        max-height:450px
    }
    .Overall-survival-chart{
        margin-top:22px
    }
    .overall-survival-sec .chart-header:before{
        width:43%;
        right:77.4%
    }
    .overall-survival-sec .chart-header:after{
        width:43%;
        left:77.4%
    }
    .progressionfree-chart{
        margin-top:20px;
        padding-bottom:20px;
    }
    .progressionfree-sec .chart-header:before{
        width:35.5%;
        right:85%;
    }
    .progressionfree-sec .chart-header:after{
        width:35.5%;
        left:85%;
    }
    .calloutBrouchure.NCCN-Category{
        margin:25px 0 46px 0
    }
    .calloutBrouchure span.NCCN-content-bold{
        display:block;
        margin-bottom:5px
    }
    .Standard-care-sec .calloutBrouchure span.NCCN-content-bold{
        display:inline
    }
    .PACIFIC-Regimen-sec .chart-header:before{
        width:53.4%;
        right:67%
    }
    .PACIFIC-Regimen-sec .chart-header:after{
        width:53.4%;
        left:67%
    }
    .PACIFIC-Regimen-sec .calloutBrouchure.NCCN-Category{
        margin:18px 0 40px 0
    }
    .calloutBrouchure.clinically-approx{
        margin:8px 0 40px 0
    }
    .calloutBrouchure.clinically-approx p{
        padding-top:25px;
        padding-bottom:20px;
        padding-left:30px;
        padding-right:30px;
        text-align:center
    }
    .studydesign-sec .calloutBrouchure.NCCN-Category.second{
        margin:10px 0 30px 0
    }
    .ovr-all-call{
        margin-top:-1em
    }
    .chart-header .chart-sur-line{
        margin-left:24px
    }
    .chart-sur-line:before{
        right:99.4%
    }
    .overall-survival .chart-header:before,.overall-survival .chart-sur-line:after{
        width:6%!important
    }
    .progressionfree-sec .chart-header em{
        padding-right:2px
    }
    .overall-survival .chart-header:before,.overall-survival .chart-header:after{
        width:6%
    }
    .nccn .first-sec{
        padding-left:55px;
        padding-right:55px
    }
.efficacy .calloutBrouchure .left-div p:first-child, .dosing .calloutBrouchure .nccn-new .left-div p:first-child {
    font-size: 50.4px;
    color: #003865;
    margin-bottom: 0;
}
.efficacy .calloutBrouchure .left-div p:nth-child(2), .dosing .calloutBrouchure .nccn-new .left-div p:nth-child(2) {
    font-size: 23.4px;
    color: #003865;
    margin-top: -10px;
    white-space: nowrap;
}                
    .np-notebook .first-sec{
        padding-left:40px;
        padding-right:40px
    }
    .efficacy .efficacy_accordion,.efficacy .accordion-header,.efficacy .accordion-footer{
        display:none!important
    }
    .efficacy .calloutBrouchure p, .dosing .calloutBrouchure .nccn-new .right-div p{
        font-size:20px
    }
    .efficacy .callout-image{
        width:15%
    }
    .efficacy .first-sec.nccn-content{
        padding-bottom:3px
    }
    .studydesign-sec .first .callout-content{
            height: 200px;
    }
.table-blocks .block {
        width: 25%;
    margin: 10px 0;
    padding: 0px 18px 0px 18px;
    text-align: center;
    border-right: 1px solid #003865;
    border-bottom:none;
}
.block.last {
    border: none;
}
.studydesign-sec .callout-content .first-sec.Secondary {
    width: 64%;
}
.Secondary ul.study-designs {
    display: flex;
}
.Secondary ul.study-designs .study-left {
    width: 36%;
}
    .studydesign-sec .callout-content .first-sec{
        float:left;
        width:34.5%;
        border-bottom:0;
        margin-top:1em;
        padding-left:1.5em;
        margin-bottom:2em
    }
    .studydesign-sec .callout-content .first-sec.Secondary{
        border-left:2px solid #7ca3dc
    }
.studydesign-sec .chart-header:before,.studydesign-sec .chart-header:after {
    width: 20%;
}

.studydesign-sec .chart-header {
    width: 74%;
}
    .Secondary .study-designs{
        border-right:none
    }
    .studydesign-sec .calloutBrouchure .study-designs{
        margin-bottom:0
    }
    nccn .first-sec{
        padding-left:41px;
        padding-right:50px
    }
    .responserates .chart-header:before,.responserates .chart-header:after{
        width:50%
    }
    .chart-header:before,.chart-header:after{
        width:20%
    }
    .chart-header.ovr-sur:before{
        width:25%!important;
        right:81%
    }
    .chart-header.ovr-sur:after{
        width:25%;
        left:80%
    }
    .responserates .chart-header:before{
        right:70%
    }
    .responserates .chart-header:after{
        left:70%
    }
    .chart-header{
        font-size:17px;
        width:71%
    }
.studydesign-sec .chart-header{
        width:76%
    }
    .chart-header.immune-mediated-chart{
        width:40%
    }
    .chart-header.immune-mediated-chart:before,.chart-header.immune-mediated-chart:after{
        width:72%
    }
    .safety .callout-image.icbook{
        height:106px;
        top:-56px;
        width:15%
    }
    .safety .lab-Abnormalities .chart-header{
        width:82%
    }
    .safety .lab-Abnormalities .chart-header:before,.safety .lab-Abnormalities .chart-header:after{
        width:11%
    }
    .calloutBrouchure p.ligHou{
        font-size:20px;
        margin-top:-40px;
        margin-bottom:5px;
        padding:0em 1.5em 1.5em 1.5em
    }
    .calloutBrouchure.icbook-image p.ligHou{
        padding:0em 3.2em 1.5em 3.2em
    }
    .responserates p.Roboto-Medium.ligHou{
        font-size:20px;
        margin-top:0;
        margin-bottom:5px;
        padding:0em 1.5em 0em 1.5em
    }
    .safety .effImage{
        margin-bottom:1.5em
    }
    .safety .callout-image.ligHouse{
        width:35%
    }
    .safety .calloutBrouchure-light p.ligHou{
        padding:0em 1.5em 1em 1.5em
    }
    .efficacy .responserates .callout-content{
        min-height:138px;
        padding:10px 0
    }
    .efficacy .responserates .first-sec{
        text-align:center;
        padding:0 18px;
        float:left;
        width:50%;
        border:0
    }
    .efficacy .responserates ul.study-designs.firstlink{
        border:0;
        padding-left:0em;
        padding-right:0;
        padding-top:5px
    }
    .efficacy .responserates .vs{
        margin-top:2.5em
    }
    .efficacy .responserates .chart-header.first{
        width:25%
    }
    h2.page-mark:before{
        left:-5px
    }
    .RecommendedDosing .page-sub-title{
        width:102%
    }
    .callout-image.how-to-order{
        background:#fff url(/content/dam/website-services/us/434-imfinzi-com/hcp-lung-cancer/Desktop/imfinzi-package-insert.png);
        max-width:291px;
        width:100%;
        top:45px;
        height:112px;
        background-size:cover;
        background-repeat:no-repeat;
        background-position:center top
    }
    .effImage img{
        max-width:680px
    }
    p.howToOrder{
        padding:2.7em 2em 1.3em 2em;
        font-size:20px
    }
    .dosing-chart img{
        margin:0 auto
    }
    .callout-image.lighthouse-image{
        max-width:182px;
        height:73px;
        top:11px
    }
    .dosing .callout-image.lighthouse-image{
        max-width:none
    }
    .lighthouse-access p.lightHouse{
        padding:1.5em 2em 1.4em 2em;
        font-size:20px
    }
    .callout-image.access-image{
        background:#fff url(/content/dam/website-services/us/434-imfinzi-com/hcp-lung-cancer/Desktop/how-to-order-imfinzi-1-3-x@2x.png);
        max-width:100px;
        height:77px;
        background-size:cover;
        background-repeat:no-repeat;
        background-position:center top
    }
    .dosing-page ul.study-designs{
        padding-left:20px;
        padding-top:10px;
    }
    .calloutBrouchure.marginTop{
        margin-bottom:60px
    }
    .dosing-page h1.page-sub-title{
        margin-bottom:5px
    }
    .page-content.lighthouse-access{
        margin-top:0
    }
    .effImage{
        margin-top:1.5em
    }
    .mobile-align{
        display:inline-block;
        text-indent:0
    }
    p.lightHouse{
        padding:2.2em 4em 1.6em 4em
    }
    .accessReimb .dowNo a{
        display:inline-block
    }
    p.accessReimb{
        padding:3.1em 2em 1.6em 2em;
        font-size:20px
    }
    .dosing .callout-image.lighthouse-image{
        width:29%
    }
}

@media screen and (min-width:768px) and (max-width:990px){
/*********************************US-52438********************************************************/
.safety .subpage-banner .content-title img{
    max-width: 50%;
}
/*********************************US-52438 End********************************************************/
	.sec-1{
	    margin-left: -10px;
	}
	.sec-2{
		margin-left: 75px;
	}
	.sec-2 .right-image img{
		max-width: 180px;
	}
	.subpage-banner .content-title h2 {
		text-align: left;
		padding-left: 6.8em !important;
		font-size: 27px;
		position: absolute;
		top: -8px;
	}
	.imfinzi-crt .subpage-banner h2 sup{
		 font-size: 16px !important;
		 top: -8px !important;
	 }
	.subpage-banner .content-title h2:before{
	     top: 30px
	 }
	 
}
@media screen and (min-width:991px) and (max-width:1120px){
    .subpage-banner .content-title h2{
		text-align: left;
		padding-left: 2.5em !important;
		font-size: 35px;
	}
	 .imfinzi-crt .subpage-banner h2 sup{
		 font-size: 20px !important;
		 top: -10px !important;
	 }
	.subpage-banner .content-title h2:before{
		top: 28px;
	 }
	 
}
@media screen and (min-width:768px) and (max-width:1080px){
    .subpage-banner .content-title h2{
        text-align:center
    }
    .callout-image.how-to-order{
        top:36px
    }
    .hero-right img{
        max-width:300px;
        margin-left:20px
    }
    .calloutBrouchure.icbook-image{
        margin-top:150px
    }
    .subpage-banner .content-title:after{
        height:146px;
        width:163px;
        right:-25px;
        top:13px;
        background-repeat:no-repeat
    }
    .Request-A-Rep{
        top:37px
    }
    .subpage-banner .content-title h2{
        text-align:left;
        padding-left:5em
    }
    .fullnavigation{
        background-size:878px 50px
    }
    header#header{
        background-size:50% 45px
    }
    ul.study-designs ul.inner-list li:before{
        font-size:10px !important
    }

}
@media screen and (min-width:768px) and (max-width:1023px){
    .container>.navbar-collapse{
        height:50px!important;
        margin-top:-1px
    }
/*    #maincontent.container{
        padding-top:125px
    }*/
    .subpage-banner{
        margin-top:-42px
    }
    a[name='isi'],a.section-link{
        height:115px
    }
    .lung-home .isi{
        margin-top:25px
    }
    .lung-home .Sticky_ISI.desktop_only{
        display:none
    }
    .Sticky_ISI.desktop_only{
        display:unset
    }
}
@media screen and (min-width:1024px){
    .content-title h2:before{
        width:23px;
        height:75px;
        left:-30px;
        top:15px;
        margin-right:-15px
    }
    .subpage-banner .content-title h2:before{
    	top: 30px;
        left:5px;
        margin-right:12px
    }
    ul.study-designs ul.inner-list li:before{
        font-size:21px;
        top:-1.5px
    }
}
@media screen and (-ms-high-contrast:active),(-ms-high-contrast:none){
    .navbar-nav>li>a,.navbar-default .navbar-nav>li>a,.navbar-nav>li>a:hover,.navbar-default .navbar-nav>li>a:hover,.navbar-nav>li>a:visited,.navbar-default .navbar-nav>li>a:visited,.navbar-nav>li>a:focus,.navbar-default .navbar-nav>li>a:focus{
        height:100%;
    }
    .navbar-nav>li:first-child>a:hover:before,.navbar-nav>li:first-child.active>a:before,.navbar-collapse .navbar-nav>li:first-child>a.currentMenuItem:before{
        top:0px !important;
    }
	.navbar-nav > li:first-child > a, .navbar-default .navbar-nav > li:first-child > a, .navbar-nav > li:first-child > a:hover, .navbar-default .navbar-nav > li:first-child > a:hover, .navbar-nav > li:first-child > a:visited, .navbar-default .navbar-nav > li:first-child > a:visited, .navbar-nav > li:first-child > a:focus, .navbar-default .navbar-nav > li:first-child > a:focus{
		padding-right: 7px;
	}
    h2.page-mark::before{
        background-size:95%;
    }
    .progression-free-image img,.clinical-trials-patients img,.tumor-response-rate img,.nsclc-patient-baseline img,.safety-chart-two img,.immune_adverse_chrt img,.nsclc-pacific img{
        width:100%;
    }
    .hero-content .content-title .hero-callout .callout-text2{
        padding-right:28px;
    }
    .overall-survival .probability-chart img.desk-graph{
        width:100%;
    }
	sup{
		top: -0.8em;
	}
	.dosing-chart.discontinue-chart .chart-head h3{
		width: 90%;
	}
}
@supports (-ms-ime-align: auto) {
	ul.study-designs ul.inner-list li:before {
		content: "○" !important;
		left: -9px !important;
		top: 0 !important;
		font-size: 13px !important;
	}	
}

/*New code here*/
ul li.bold-text{
	font-family: 'Roboto-Bold', sans-serif;
}
p.add-content {
    margin-bottom: 20px;
}
/*Modification of Table structure for mobile version*/
.mob-brk{
    display: none;
}
@media screen and (max-width: 767px){
    .baseline-disease-table .base-table {
        width: 49%;
        margin-right: 2%;
    }

    .baseline-disease-table .tablehead-cell1 {
        width: 25%;
    }
    .baseline-disease-table .tablehead-cell2 {
        width: 25%;
    }
    .baseline-disease-table p.tablehead-header {
        float: left;
        width: 50%;
        margin-top: 38px;
    }
    .baseline-disease-table .base-table .table-body {
        clear: both;
         height: 357px;
    }
    .baseline-disease-table .disease-table .table-body {
        clear: both;
         height: 353px;
    }
    .baseline-disease-table .cell ul li.no-bg {
        background-color: #fefefe;
        border-top: 1px solid #80a1d4;
    }
    .baseline-disease-table .cell ul li:first-child {
        border-left: 1px solid #80a1d4;
    	text-indent: 0px;
    	padding-left: 3px;
    }                                        
    .baseline-disease-table .cell ul li {
        text-align: center;
        width: 25%;
    }
    .baseline-disease-table .cell ul {
        clear: none;
    }
    .disease-table p.cellhead-2.stage {
        padding: 10px 0 10px 7px;
    }
    .baseline-disease-table .cell p.cellhead-2 {
        text-align: left;
        float: left;
    }
    .disease-table p.cellhead-2.muta {
        border-bottom: 1px solid #80a1d4;
        height: 106.5px;
    }            
    .disease-table .cell p.cellhead-2 {
     clear: both;
     }
    .base-table p.cellhead-2.smoking {
        border-bottom: 1px solid #80a1d4;
        height: 154px;
        padding-top: 50px;     
    }    
    .base-table .cell li.desk {
        height: 77px;
        padding-top: 26px;
    }
    .baseline-disease-table .cell ul li.never:nth-child(3) {
        border-right: 0px solid #80a1d4;
    }                            
    .base-table .cell ul li {
        padding: 12.8px 0;
    }                                                       

    .page-content ul li.current {
        font-size: 14.5px;
        padding-left: 4px;
    }
    .baseline-disease-table p.cellhead-2 {
        width: 25%;
      padding: 23px 0 20px 7px;                                            
    }
    .base-table p.cellhead-2 {
        padding-top: 40px;
    }

    .baseline-disease-table .base-table,.baseline-disease-table .disease-table {
        width: 100%;
    }
    .baseline-disease-table .cell ul li {
        border-bottom: 1px solid #80a1d4;
    }
    .disease-table ul li {
        padding: 5px 0 4.8px 0;
    }
    .mob-brk{
    	display: block;
    }
    .baseline-disease-table .cell ul li {
        margin-bottom: -0.7px;
    }
    .baseline-disease-table .base-table .cell ul li.never.unknown {
       height: 77px;
    }
	/*New code here*/
	.imfinzicrt .immune-response-sec .right-content p:first-child {
        border-top: 10px solid #ac162c;
        width: 70px;
        margin: 0 auto;
        margin-bottom: 8px;
    }
    .imfinzicrt .immune-response-sec .left-img img{
        max-width: 450px;
        width: 100%;
    }
    .imfinzicrt .immune-response-sec .right-content {
        padding-bottom: 30px;
    }
    .imfinzicrt .immune-response-sec .right-content p.mobile-only {
        padding-bottom: 10px;
    }
}

/*New code here*/
.efficacy sup.move-up {
    top: -0.8em;
}
.safety .adverse-table p.tablehead-header {
    padding: 5px 0 5px;
	font-family: 'HelveticaNeueLTStd-BdCn', sans-serif;
	font-size: 15px;
	font-weight:300;
	letter-spacing: normal;
}

.safety .adverse-table p.tablehead-header.laboratory {
    padding: 4px 0 6px;
}
.imfinzicrt .first .left-img img,.imfinzicrt .third .left-img img {
    border-radius: 0;
    margin-top: -1px;
}
.imfinzicrt .flex-center.third {
    border-radius: 0;
}
.imfinzicrt .immune-response-sec .flex-center {
    margin-bottom: 20px;
}
.pink-var {
    color: rgb(255, 0, 255) !important;
}
.dosing .dosing-chart ul li span.no-space {
    font-family: 'Roboto-Regular', sans-serif;
}
.dosing .dosing-chart.discontinue-chart .chart-head h3 img {
    margin-right: 0;
}
.dosing .page-content.dose-modification ul.study-designs li::before {
    font-size: 2.2em;
}

@media all and (-ms-high-contrast: none), (-ms-high-contrast: active) {
    /* IE10+ CSS styles go here */
    .efficacy .base-table .cell ul li{
        padding-top: 12px;
        padding-bottom: 13.5px;
    }
 .base-table .cell ul li.never.unknown:first-child {
    padding-bottom: 14px;
}
.base-table .cell ul li {
    padding: 12.9px 0;
} 
.base-table p.cellhead-2.smoking {
    height: 154.5px; 
}
.baseline-disease-table .table-body {
     height: 361px;
}
.safety .adverse-table p.tablehead-header {
    padding: 4px 0 5px;
}
}
@supports (-ms-ime-align:auto) {
  /* IE Edge 12+ CSS styles go here */ 
    .efficacy .base-table .cell ul li{
       padding-top: 12px;
       padding-bottom: 13.4px;
    }
 .base-table .cell ul li.never.unknown:first-child {
    padding-bottom: 15px;
}
.base-table .cell ul li.never.desk {
    padding-bottom: 65px;
}
.base-table .cell ul li {
    padding: 12.9px 0;
}
.base-table p.cellhead-2.smoking {
    height: 154.5px;   
}
.baseline-disease-table .table-body {
     height: 361px;
}
.safety .adverse-table p.tablehead-header {
    padding: 4px 0 5px;
}
}
@-moz-document url-prefix() {
    .efficacy .base-table .cell ul li{
       padding-top: 12px;
       padding-bottom: 13.4px;
    }
	.efficacy .base-table .cell li.desk{
		padding-top: 26px !important;
	} 
}

@media not all and (min-resolution:.001dpcm) {
@media{ 
    .base-table .cell ul li 
	{
        padding: 12.6px 0 !important;
    }
}
}